Protein Alignment sv and Pax2

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_006231505.2
• Gene: Pax2 / 293992
• RGDID: 1305568
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 186/477 - (38%)
• Similarity: 220/477 - (46%)
• Gaps: 147/477 - (30%)

  Fly   163 DSHSSQGSISG--DGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVS 225
            |.|......|.  .|||||||||||||||||||||||||||||||.|||||||||||||||||||
  Rat     2 DMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVS 66

  Fly   226 KILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPS 290
            |||.|||||||.|.|||||||||||||.|||.||.|||:||||||||||||||||.||..|.|||
  Rat    67 KILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS 131

  Fly   291 VSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNT 355
            |||||||:|.|                                    :.:|..||.:.:...|
  Rat   132 VSSINRIIRTK------------------------------------VQQPFHPTPDGAGTGV-- 158

  Fly   356 NVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNN 420
                :|..|..:|::.:..|                 :|.:......|||||||||.
  Rat   159 ----TAPGHTIVPSTASPPV-----------------SSASNDPVGSYSINGILGIP-------- 194

  Fly   421 NNNSSVNNNNNTESSCKRKRIE-------AH--------------DENHDTNIHSDNDDG----- 459
                    .:|.|   ||||.|       ||              |.:..:..:.|:..|
  Rat   195 --------RSNGE---KRKREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLR 248

  Fly   460 KRQRMSTYSGDQL-----------YTNIWSGKWCIKDDHKLLAELGN---LTASTGNCPATYYEA 510
            |..|..|::..||           |.:::.....||      :|.||   |.|.|......  ::
  Rat   249 KHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIK------SEQGNEYSLPALTPGLDEV--KS 305

  Fly   511 SNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSI--YTPAIGP----SIGTGSLTPLVPIS 569
            |...||.|..||  ..||..|   |..:|......:::  |.|.:.|    |..|.:|..:||.|
  Rat   306 SLSASTNPELGS--NVSGTQT---YPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGS 365

  Fly   570 MHEMKLSANSIQEQTVPPFYTA 591
                :.|.|....    |.|||
  Rat   366 ----EFSGNPYSH----PQYTA 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	111/123 (90%)
Pax2	XP_006231505.2	PAX	16..140	CDD:128645	111/123 (90%)
		Pax2_C	305..>390	CDD:463563	26/88 (30%)