DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sv and Gm4981

DIOPT Version :9

Sequence 1:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001030041.1	Gene:	Gm4981 / 245263	MGIID:	3645498	Length:	291	Species:	Mus musculus

Alignment Length:	272	Identity:	57/272 - (20%)
Similarity:	90/272 - (33%)	Gaps:	100/272 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   461 RQRMSTYSG---DQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGS 522
            |:.::..:|   |.::|      | :|:........|..||...:..|:  :.|.|....|: |.
Mouse    35 REELALETGLPEDMIHT------W-LKNKRARRHRRGRPTAQDQDLLAS--QVSGGAPAGPV-GR 89

  Fly   523 GATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANS----IQEQ 583
            |...:...:....::.:|...|.|:.|:|:.                ..|.:||..|    ..::
Mouse    90 GHEVAQESSLPQEEAGSTGMDTTSTSYSPSF----------------CRESQLSQVSQPRGAGQK 138

  Fly   584 TVPPFYTALAFDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKE 648
            .||               |...|    ||...:::.|..|                   ..:|||
Mouse   139 EVP---------------TQAGN----VGPLELLLDELQD-------------------EVQVKE 165

  Fly   649 ----PLTNSDGCSEDNNKEPEKSNSS-QSSD-------HIASPHLHHIGEEQLRGNRRSNLNAST 701
                ||   |..|:...:|||.|..| ||.|       |.:.|.:            .|.|...:
Mouse   166 HVPDPL---DLGSDPGAREPEGSQDSLQSLDEAANSGWHTSVPSI------------SSTLCRES 215

  Fly   702 HPSSLIPLQPSG 713
            .||.:  .||||
Mouse   216 QPSQV--AQPSG 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645
Gm4981	NP_001030041.1	homeodomain	6..56	CDD:238039	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900