Protein Alignment sv and Pax9

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_035171.1
• Gene: Pax9 / 18511
• MGIID: 97493
• Length: 342
• Species: Mus musculus
• Alignment Length: 269
• Identity: 121/269 - (44%)
• Similarity: 153/269 - (56%)
• Gaps: 56/269 - (20%)

  Fly   177 GGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGV 241
            |.|||||||||||||||:.:|.||||||..|:||||||||||||||||||||:||.||||...|.
Mouse     6 GEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGA 70

  Fly   242 IGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKA 306
            ||||||:|.||.||..|..||:.:|.:|||||||||||:.:|.:.||||||||:||:|||....|
Mouse    71 IGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLA 135

  Fly   307 KHVHH--HQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPT 369
            :..|:  ::||..:                      |||....:...|..:.::|:|   |.:||
Mouse   136 QQGHYDSYKQHQPA----------------------PQPALPYNHIYSYPSPITAAA---AKVPT 175

  Fly   370 -SGTDSVQVSVGHINANSNETTHINSTAEQRT--TGYSINGILGIQ----------HGHHSHNNN 421
             .|..::..||                |..||  :.:|:..||||:          ..:||....
Mouse   176 PPGVPAIPGSV----------------ALPRTWPSSHSVTDILGIRSITDQGVSDSSPYHSPKVE 224

  Fly   422 NNSSVNNNN 430
            ..||:..||
Mouse   225 EWSSLGRNN 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	88/121 (73%)
Pax9	NP_035171.1	PAX	6..131	CDD:238076	90/124 (73%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	7..63		45/55 (82%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	82..130		29/47 (62%)
		Interaction with KDM5B. /evidence=ECO:0000250	168..189		9/39 (23%)