DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sv and Pax4

DIOPT Version :9

Sequence 1:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_035168.1	Gene:	Pax4 / 18506	MGIID:	97488	Length:	349	Species:	Mus musculus

Alignment Length:	177	Identity:	91/177 - (51%)
Similarity:	115/177 - (64%)	Gaps:	12/177 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 DGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFK 238
            ||...||||||:||||||||...||:||:||..|:|||||||.|:||:|||||||.|||.||..:
Mouse     4 DGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLE 68

  Fly   239 AGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAA 303
            ...||||||::|||.||..||..|.|.|.:|||||:.:|..|.:|:||..||||||||::|  |.
Mouse    69 PKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLR--AL 131

  Fly   304 EKAKHVHHHQQHH---VSQSLGGGHIATESVDSSTGTIGEPQPPTSN 347
            ::.:.:|..|...   ::..|...|       |:.|....|.|.||:
Mouse   132 QEDQSLHWTQLRSPAVLAPVLPSPH-------SNCGAPRGPHPGTSH 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	78/123 (63%)
Pax4	NP_035168.1	PAX	5..129	CDD:128645	78/123 (63%)
		PAI subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	8..64		41/55 (75%)
		RED subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	83..131		26/49 (53%)
		Homeobox	174..226	CDD:278475
		Transcription repression	278..349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910