Protein Alignment sv and Pax4

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_035168.1
• Gene: Pax4 / 18506
• MGIID: 97488
• Length: 349
• Species: Mus musculus
• Alignment Length: 177
• Identity: 91/177 - (51%)
• Similarity: 115/177 - (64%)
• Gaps: 12/177 - (6%)

  Fly   174 DGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFK 238
            ||...||||||:||||||||...||:||:||..|:|||||||.|:||:|||||||.|||.||..:
Mouse     4 DGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLE 68

  Fly   239 AGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAA 303
            ...||||||::|||.||..||..|.|.|.:|||||:.:|..|.:|:||..||||||||::|  |.
Mouse    69 PKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLR--AL 131

  Fly   304 EKAKHVHHHQQHH---VSQSLGGGHIATESVDSSTGTIGEPQPPTSN 347
            ::.:.:|..|...   ::..|...|       |:.|....|.|.||:
Mouse   132 QEDQSLHWTQLRSPAVLAPVLPSPH-------SNCGAPRGPHPGTSH 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	78/123 (63%)
Pax4	NP_035168.1	PAX	5..129	CDD:128645	78/123 (63%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		41/55 (75%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		26/49 (53%)
		Homeodomain	172..227	CDD:459649	91/177 (51%)
		Transcription repression	278..349