Protein Alignment sv and Otx1

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_035153.1
• Gene: Otx1 / 18423
• MGIID: 97450
• Length: 355
• Species: Mus musculus
• Alignment Length: 275
• Identity: 56/275 - (20%)
• Similarity: 96/275 - (34%)
• Gaps: 70/275 - (25%)

  Fly   509 EASNGFSTTPI--------SGSGATASGNDT-SMLYDSITTISQTQSSIYTPAIGPSIGTGSLTP 564
            ::.||..|.|:        ..||:.:||..| ..:..|.::.|...|:...||...:.|.|.
Mouse    98 QSGNGTKTRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGG--- 159

  Fly   565 LVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCP 629
             .|::      :|:|:...|....::..:.... ::.||:.          :..|.::.||..|.
Mouse   160 -NPVA------AASSLSTPTASSIWSPASISPG-SAPTSVS----------VPEPLAAPSNASCM 206

  Fly   630 ISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNS----SQSSDHIASPHLHHIGEEQLR 690
            ..:......|...|    .|::...|.|.... .|..|:|    ...|.::|..|.||
Mouse   207 QRSVAAGAATAAAS----YPMSYGQGGSYGQG-YPAPSSSYFGGVDCSSYLAPMHSHH------- 259

  Fly   691 GNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNHYSAG 755
                       ||..|.|:.||..:...:.:|..:..     ||.:.|.:..    ...:|:..|
Mouse   260 -----------HPHQLSPMAPSSMAGHHHHHPHAHHP-----LSQSSGHHHH----HHHHHHHQG 304

  Fly   756 CSSVVPGSDYAYNPA 770
            ..    ||..|:|.|
Mouse   305 YG----GSGLAFNSA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645
Otx1	NP_035153.1	Homeodomain	39..95	CDD:459649
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..144		11/45 (24%)
		TF_Otx	178..274	CDD:427350	25/129 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..306		14/75 (19%)