Protein Alignment sv and Pax3

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 635
• Identity: 176/635 - (27%)
• Similarity: 253/635 - (39%)
• Gaps: 203/635 - (31%)

  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKA 239
            |.|.||||||||:||||||:.:|.:|||:||:|:|||.||||||||||||||||.||.||||.:.
  Rat    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly   240 GVIGGSKPK-VATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAA 303
            |.||||||| |.||.|...|..||||||.||:|||||:||.:|:|.::.|||||||:||:|:|
  Rat    99 GAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSK-- 161

  Fly   304 EKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIP 368
                             .|.|.  .|..|.......|.:....:|        :....|..||.|
  Rat   162 -----------------FGKGE--EEEADLERKEAEESEKKAKHS--------IDGILSERASAP 199

  Fly   369 TSGTDSVQVSVGHINANSNETTHINSTAE------QRTTGYSINGILGIQHGHHSHNNNNNSSVN 427
                            .|:|.:.|:|..:      ||
  Rat   200 ----------------QSDEGSDIDSEPDLPLKRKQR---------------------------- 220

  Fly   428 NNNNTESSCKRKRIE-AHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIW----SGKWCIKDDH 487
            .:..|.::.:.:.:| |.:..|..:|::..:..:|.:::     :....:|    ..:|..:...
  Rat   221 RSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLT-----EARVQVWFSNRRARWRKQAGA 280

  Fly   488 KLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSI-TTISQTQSSIYTP 551
            ..|....:|.  .|..|.|      ...|.|      |...::||....|| ..:|...|:::.|
  Rat   281 NQLMAFNHLI--PGGFPPT------AMPTLP------TYQLSETSYQPTSIPQAVSDPSSTVHRP 331

  Fly   552 AIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHI 616
                       .||.|.::|:..:.:|:.....    |...:....::|.|     .|.|
  Rat   332 -----------QPLPPSTVHQSTIPSNADSSSA----YCLPSTRHGFSSYT-----DSFV----- 371

  Fly   617 VMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQSSDHIASPHL 681
              |.|..||   |::    |.|....|.:|...|||..|...    :|:       :|:..||
  Rat   372 --PPSGPSN---PMN----PAIGNGLSPQVMGLLTNHGGVPH----QPQ-------TDYALSP-- 414

  Fly   682 HHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVL 746
                   |.|.                |:|:...|.......|:..:|:          |.||..
  Rat   415 -------LTGG----------------LEPTTTVSASCSQRLEHMKNVD----------SLPTSQ 446

  Fly   747 PSFNHYSAGCSSVVPGSDYAYNPAYTQYGGAYGSYGYGTGSGLINSSYYY 796
            |.       |......:.|:.:|.   .|..||.||        .|:::|
  Rat   447 PY-------CPPTYSTTGYSMDPV---TGYQYGQYG--------QSAFHY 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	87/124 (70%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	87/124 (70%)
		Homeodomain	220..276	CDD:459649	9/88 (10%)
		Pax7	347..391	CDD:403540	14/66 (21%)