DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sv and pax10

DIOPT Version :9

Sequence 1:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001373372.1	Gene:	pax10 / 100192208	ZFINID:	ZDB-GENE-081022-10	Length:	275	Species:	Danio rerio

Alignment Length:	270	Identity:	48/270 - (17%)
Similarity:	97/270 - (35%)	Gaps:	101/270 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   419 NNNNNSSVNN----------NNNTESSCKRKRIE-----------AHDENHDTNIHSDNDDGKRQ 462
            |::|.|..||          .:.|:...:...::           ..||..|:.:|.......::
Zfish    12 NSSNWSGPNNWYHPADTITPQHGTDGCVEDLNVQMAGAGEGVVQGERDEVDDSQLHLQLKRKLQR 76

  Fly   463 RMSTYSGDQL-----------YTNIWS-----------------------GKWCIKDDHKLLAEL 493
            ..::::.:|:           |.::::                       .||  :.:.||..:
Zfish    77 NRTSFTQEQIDALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKW--RREEKLRNQ- 138

  Fly   494 GNLTASTGNCPATYYEASNGFSTTPI------SGSGATASGNDTSML-YDSITTISQTQSSIYTP 551
             ..:.|:.:|..|:...|..|: :|:      :.||:..|.:|:|:. |.|::..|..||.
Zfish   139 -RRSGSSSSCSQTHTPLSTSFN-SPVYHSHHSNSSGSMHSRSDSSLSGYSSLSVFSSMQSL---- 197

  Fly   552 AIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHI 616
               ||..|.:.:.::|.|            ...:||.  :..||.:|||             .|:
Zfish   198 ---PSQSTPTYSCMLPPS------------PSALPPL--SRKFDSSYTS-------------PHL 232

  Fly   617 VMPESSDSNT 626
            ..|.::.:||
Zfish   233 PPPPTASANT 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645
pax10	NP_001373372.1	Homeobox	78..131	CDD:395001	4/54 (7%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910