Protein Alignment Cals and clstn2b

DIOPT Version :10

• Sequence 1: NP_001259086.1
• Gene: Cals / 43824
• FlyBaseID: FBgn0039928
• Length: 979
• Species: Drosophila melanogaster
• Sequence 2: XP_698154.5
• Gene: clstn2b / 569664
• ZFINID: ZDB-GENE-121214-77
• Length: 917
• Species: Danio rerio
• Alignment Length: 993
• Identity: 269/993 - (27%)
• Similarity: 473/993 - (47%)
• Gaps: 164/993 - (16%)

  Fly    42 LEKSYHGLIREN--ETLVEITPLIKVNEE-------KICNFHILKKPYHEIPFKIELVNNL---G 94
            :|.||||:|.||  |.|:: .||:.::::       :||.||:...   ..||:..|:|..   |
Zfish    29 IETSYHGVITENTDEVLLD-PPLVALDKDAPVPYAGEICGFHVQGL---SAPFEAVLLNGTSGEG 89

  Fly    95 ILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEV 152
            .|:||..::||..:.:.|.|.|..|...|       |:.|.|.:.|.||||::|.|.:..|...|
Zfish    90 RLRARGPIDCERHREFSFIIQAHDCGTGPQGHGQKRSHKAAVRVQVGDVNEFSPVFGQLEYHGSV 154

  Fly   153 DEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVV 217
            .||::|:.||:|:|||:||:|.:..:|.|:|.:.|..|::|..|:|:|||.||.:...::.:.|.
Zfish   155 TEGKVYDSILQVQASDQDCSPQYSQICNYQITSPDTAFAVDRNGNIRNTESLSFEKKSHYKIRVT 219

  Fly   218 AYDC----AMKESAPIMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNE 278
            |.||    ||:|:   :|.|.|:.:|:..:.|..:.:||..|:...| |||...|:.|:.|..
Zfish   220 ALDCGQKRAMQEA---IVHIHVKPICKPGWQGWRKLVDYEPGAGSKL-LFPKMHLETCEGSVS-- 278

  Fly   279 EDLRIHSSIALKTKHISFGCDRDIS---NCTSGQKVKDLLPHG---AEWTKELSYDEGLEP--IF 335
               .|.:::.|:|..:..|||.:.|   .|.|......|||..   ..||..|..|.|.:.  .:
Zfish   279 ---WIRTTVELETSGVGRGCDSERSLQKLCGSSSGSTALLPATGGVCNWTVTLVRDSGRDSDLAY 340

  Fly   336 HFDGSTGVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMALFV 400
            .|||.....:|..|:.. :.:.| |:|.|..:|..... .:..||.::|::|..:|||||.:|:|
Zfish   341 RFDGHQAAKIPDWVVPQ-NLTDQ-FTITTWMKHGPSPG-QRAEKETLLCNSDKTEMNRHHYSLYV 402

  Fly   401 RNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIE 465
            .||||:||||.::.:.|  .|.|||:.||:.::||.|||:|||:| |...|.|::|||.:|..:
Zfish   403 HNCRLVFLLRTDYTQTD--SFRPAEFHWKLEQICDKEWHYYVLSV-DFPVVTLYVDGVTYEPYL- 463

  Fly   466 NRHSNPEVIDDWPLHAAHGVNTSLAIGACYQSLE---NRLKHGFNGDISEVKVSLNSVLTAEDIK 527
                   |.||||:|::. ::..|.:|||:|..|   .:....|.|.:|.:.:....:.:.:.|.
Zfish   464 -------VTDDWPIHSSQ-IDVQLTVGACWQGGEVSKAKFSQYFRGSLSGLTIRPGKIESQKIIS 520

  Fly   528 CGTTCAEHLLAPKPLQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPT 592
            |...|.|      .|...:.::.....:...|...:.:.:.|::...:...:|||.|||::|.||
Zfish   521 CLQACKE------GLDITSLENLGQRIKFHLNPAQSVLVMEAEDLEQMNGALRKVSYINSRQFPT 579

  Fly   593 VGRRNIEVLTTLNCKNES-SLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSDLTPPSYSPKIA 656
            :|.|::.:.|.:.|..|. .:.:|.||..:||.:|                        ...:|.
Zfish   580 MGSRHLRISTAVQCFGEDVCISVPDIEVVVMVMQP------------------------SEARIT 620

  Fly   657 ISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGKLEEKNH----------IDSCSVVVF-PSLN 710
            |:|..:..:...::.||:.:.....|.|......|:...:|          :|.|.::|. ..|.
Zfish   621 ITGAEHLTIPAYDLALGLSLFRDLHIISTVTKRDKVTNMDHRSSAKETAHNLDYCDILVLGEELR 685

  Fly   711 PDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLS 775
            ...|.:::.....|...::...  :..|:.:.|.|:||:|..|:|.:.|.::: |....|.|:|:
Zfish   686 AGLESLELHHSALLGKHLEYAN--SSTGMSIYGVDSISHYTEVIRQVRYQSRR-AVDSVRTFRLT 747

  Fly   776 CAQQSSQYKSGEYTLTLTVLHPKQTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDNN 840
            |::.:.:|.|.:|||.:.:||.::           :...||.:                    ..
Zfish   748 CSELNGRYTSDQYTLQVNILHSEE-----------AREHVNHL--------------------MT 781

  Fly   841 QPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQK 905
            .|...::...:::.:||          :.:....:..|.::::....|.|:|.||.......|:.
Zfish   782 PPKSMQITHRTVMESNN----------YFNLVVPAVSTSVVVVCIAALLVVLLGVYQLNQTQNKD 836

  Fly   906 YIEHHQPCPKISDDGLIWDDSALTITINPMQ-------ADVTSDASSESE----NSESEDEEVAL 959
            .|:.|    .::::.:..:.|:|:||:||:|       |:||.:...|.:    ::||:.:|...
Zfish   837 SIQTH----TLAEEQVDCEGSSLSITVNPLQNCQELQSAEVTEEEEDEEDCAISSTESDSDEEET 897

  Fly   960 KDGFTH-INQLEWDNSNI 976
            ...||| ..:.:|..:.:
Zfish   898 DTPFTHRQTKQQWGKATL 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cals	NP_001259086.1	Cadherin_repeat	45..138	CDD:206637	36/111 (32%)
		CA_like	148..235	CDD:481204	36/90 (40%)
		Laminin_G_3	<435..527	CDD:463865	30/94 (32%)
		CLSTN_C	573..936	CDD:466150	76/374 (20%)
clstn2b	XP_698154.5	Cadherin_repeat	32..140	CDD:206637	36/111 (32%)
		Cadherin_repeat	149..241	CDD:206637	37/94 (39%)
		LamG	397..508	CDD:473984	49/122 (40%)
		CLSTN_C	530..863	CDD:466150	78/404 (19%)