Protein Alignment Cals and Cals

DIOPT Version :10

• Sequence 1: NP_001259086.1
• Gene: Cals / 43824
• FlyBaseID: FBgn0039928
• Length: 979
• Species: Drosophila melanogaster
• Sequence 2: XP_001237121.3
• Gene: Cals / 4576322
• VectorBaseID: AGAMI1_003887
• Length: 1020
• Species: Anopheles gambiae
• Alignment Length: 1010
• Identity: 580/1010 - (57%)
• Similarity: 726/1010 - (71%)
• Gaps: 84/1010 - (8%)

  Fly    29 ENDDEYLTQKEIILEKSYHGLIRENETLVEITPLIKVNEEKICNFHILKKPYHEIPFKIELVNNL 93
            |::|:|...:|.:||.||||||:||||.|||||||||:|.|||.|||:|| ..||||:|||||.|
Mosquito    33 EDEDDYYDSRERVLENSYHGLIKENETFVEITPLIKVDETKICGFHIIKK-NKEIPFQIELVNEL 96

  Fly    94 GILKARRTLNCENRKSYHFEICAIYCDGTPSNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLY 158
            |||||::|||||.||:|.|:|.|::|||:.|.:|:|||:|||:|||:||||:||||.||||||||
Mosquito    97 GILKAKKTLNCEKRKNYKFDITAVFCDGSHSKSASVHISVIDINEYSPTFLQPSYVTEVDEGRLY 161

  Fly   159 NEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAM 223
            .||:||||:|||||||||||||||||.||:||:|||||||:||||||||.|||||||||||||||
Mosquito   162 QEIIRVEATDKDCTPLFGDVCKYEILTNDQPFTIDNEGSIRNTEPLSHKISHNHILSVVAYDCAM 226

  Fly   224 KESAPIMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIA 288
            |:|||:||:|:||||||...:|:.|||||.:.|.||:.|||...|:|||:.||. ||:.|.||::
Mosquito   227 KQSAPVMVNIRVRRVCEAHVMGVAERIDYVANSMESVSLFPKIHLELCDMQCKG-EDMVIQSSVS 290

  Fly   289 LKTKHISFGCDRDISNC------------TSGQKVKDLLPHGAEWTKELSYDEGLEPIFHFDGST 341
            |||||||||||||.|.|            ..|..:.|||....:|||:|:||||.|.|||||||:
Mosquito   291 LKTKHISFGCDRDASQCLRRLSESGSGRERDGDGLVDLLQKNTDWTKDLTYDEGAEAIFHFDGSS 355

  Fly   342 GVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMALFVRNCRLI 406
            |.:||..|:...||::..|||:|:|||||.|..:||.||||||||||||||||||||||||||||
Mosquito   356 GAIVPKNVVQPQDFAAHQFSIVTMFRHNSIVSTDKHTKEHIVCSADDHKMNRHHMALFVRNCRLI 420

  Fly   407 FLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNP 471
            .||||:||:||||||||||||||||:|||||||||.:|| |..||||:|||:|||:::|:|||||
Mosquito   421 LLLRKDFNDGDLNIFSPAEWRWKIPQVCDNEWHHYTINV-DLPKVDLYIDGIRFESNVEDRHSNP 484

  Fly   472 EVIDDWPLHAAHGVNTSLAIGACYQSLENRLKHGFNGDISEVKVSLNSVLTAEDIKCGTTCAEHL 536
            |||||||||||||:||:||||||||..||||||||:|||:|:|:|...||||..|:|||.|||.|
Mosquito   485 EVIDDWPLHAAHGINTTLAIGACYQGSENRLKHGFSGDIAEIKLSTRKVLTASQIRCGTDCAEKL 549

  Fly   537 LAPKPLQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVL 601
            |.|.      :.......||:.|.:||:|.|...||.:|||.::::||||:|:.||:|||||:|:
Mosquito   550 LPPA------DHYLEPEQQIQSNTQMNKIIIEGSNKTNIEQLLQQIQYINSKESPTIGRRNIQVM 608

  Fly   602 TTLNCKNESSLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSD--------LTPP---SYSPKI 655
            ||::|.|:.::|||.|:|||||:...:.|.....:.||:..:|.        :..|   ...|:|
Mosquito   609 TTVSCPNKKAIRLPTIDTYIMVSSAGSSLSGGSMLASATSSSSSSGLYNKILVDKPLATDQKPQI 673

  Fly   656 AISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGK--LEEKNHIDSCSVVVFPSLNPDHEDIKI 718
            .|||.||.||||.:||.||.||.:.   ::|...||  ..|...:|||:|.||||||||||:|.|
Mosquito   674 VISGNSNHLVSYPDIKEGVKILAQI---NISVYTGKDIRPELQKLDSCNVNVFPSLNPDHEEITI 735

  Fly   719 D----GDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQ 779
            |    .|||| ...||||.|:|:||||||.|||.||.:||:||||.||||||||||||||:|:|.
Mosquito   736 DDKDGADESL-FKFDIKTQISKEGVEMIGYDTIENYQHVLKSLVYINKKPAYYLNRVFKLTCSQV 799

  Fly   780 SSQYKSGEYTLTLTVLHPKQTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDN-NQPT 843
            ...::|.|||||||||||||.  .::::..:|....|.:.......|....:.:|:.:|| ||
Mosquito   800 DDHFRSAEYTLTLTVLHPKQQ--PTSSIASASAPSSNVLLAISTAPSEQHPAVAVDSHDNANQ-- 860

  Fly   844 ESKVYSYSLLHTNNVQEPKSHIHSF-------IHKAEGSHVTMLIILVSVFLAVLLCGVSIARLK 901
                |::.:||:::|||.:|.:.|.       ..|...||.||||:::.....:|:|||.||||:
Mosquito   861 ----YAHVMLHSHDVQESQSKVRSSGGAALLGHEKLASSHSTMLIVVICGSFVLLICGVGIARLR 921

  Fly   902 NN------------------------QKYIEHHQPCPKIS-DDGLIWDDSALTITINPMQADVTS 941
            |:                        :...:.|.||||:: |..|.||||||||||||||.|..|
Mosquito   922 NSNAALAGGSSGHGAAGGAAGGSAFARNLTDKHLPCPKVAPDQQLDWDDSALTITINPMQHDALS 986

  Fly   942 DASSESENSESEDEEVALKDGFTHINQLEWDNSNI 976
            |.||||:||:|||||| |...:.:::|||||||.|
Mosquito   987 DESSESDNSDSEDEEV-LNGRYKNVSQLEWDNSTI 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cals	NP_001259086.1	Cadherin_repeat	45..138	CDD:206637	65/92 (71%)
		CA_like	148..235	CDD:481204	74/86 (86%)
		Laminin_G_3	<435..527	CDD:463865	67/91 (74%)
		CLSTN_C	573..936	CDD:466150	180/412 (44%)
Cals	XP_001237121.3	None