Protein Alignment Cals and clstn2

DIOPT Version :9

• Sequence 1: NP_001259086.1
• Gene: Cals / 43824
• FlyBaseID: FBgn0039928
• Length: 979
• Species: Drosophila melanogaster
• Sequence 2: XP_002941239.2
• Gene: clstn2 / 100493355
• XenbaseID: XB-GENE-958942
• Length: 949
• Species: Xenopus tropicalis
• Alignment Length: 972
• Identity: 304/972 - (31%)
• Similarity: 479/972 - (49%)
• Gaps: 161/972 - (16%)

  Fly    42 LEKSYHGLIRE-NETLVEITPLIKVNEE-------KICNFHILKKPYH--EIPFKIELVNNL--- 93
            :|.||||:|.| |:|::...||:.::::       :||.|.|     |  :.||:..::|..
 Frog    33 IETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKI-----HGQDTPFEAVVLNKTSGE 92

  Fly    94 GILKARRTLNCENRKSYHFEICAIYCD----GT---PSNTANVHITVIDVNEYAPTFLEPSYVIE 151
            |.|:|:..::||.:|.|.|.|.|..|.    ||   .|:.|.|||.|.||||:||.|.|..|...
 Frog    93 GRLRAKGPIDCEIQKEYTFIIQAYDCGAGQAGTSWKKSHKAVVHIQVNDVNEFAPVFKEKKYSAM 157

  Fly   152 VDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSV 216
            |.||::|:.||:|||.|:||:|.:..:|.|||:.:|.||:||..|:|:|||.||:...|.:.:.|
 Frog   158 VTEGKIYDSILQVEAMDEDCSPQYSQICNYEIVTSDVPFAIDRNGNIRNTEKLSYDKQHQYEIKV 222

  Fly   217 VAYDCAMKESA-PIMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCD--ISCKNE 278
            .||||..|.:. .:.|.:.::.||:..:....:||:|..|| .|:.|.|..||:.||  :|.
 Frog   223 TAYDCGQKHATEDVTVIVDIKPVCKPGWQDWDKRIEYNPGS-GSIALLPTVRLETCDGPVSF--- 283

  Fly   279 EDLRIHSSIALKTKHISFGCDRDISN-------CTSGQKVKDLLPH---GAEWTKELSYD-EGLE 332
                |.:||.|:|.||..||||:..:       |.:.....||||.   ...||..|..| .|:
 Frog   284 ----IRTSIELQTNHIGKGCDRETYSDASLKALCGASSGAIDLLPSPSASTNWTAGLIMDNSGM- 343

  Fly   333 PIFHFDGSTGVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMA 397
             ||.|||..||.:|..::.. :.:.| |:|....:|.....:... ||.|:|::|..:|||||.|
 Frog   344 -IFKFDGKQGVKIPDAILPK-NLTDQ-FTITMWMKHGPSPGLRAE-KETILCNSDKTEMNRHHYA 404

  Fly   398 LFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFEN 462
            |:|.||||:||||::|::.|  .|.|||:.||:.::||.|||:|::|:. ...|.|::||..:|.
 Frog   405 LYVHNCRLVFLLRRDFDQAD--TFRPAEFHWKLDQICDKEWHYYIINIA-FPLVTLYMDGATYEP 466

  Fly   463 SIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQSLE---NRLKHGFNGDISEVKVSLNSVLTAE 524
            .:        |.:|||:|.:| :...|.:|||:|..|   .:....|:|.|:.:.:....:.:.:
 Frog   467 YL--------VTNDWPIHPSH-IAMQLTVGACWQGGEVTKPKFAQYFHGSIAGLMLRPGKIESHK 522

  Fly   525 DIKCGTTCAEHLLAPKPLQSNNEKSYSDNSQ-IKE--NIEMNEIYISAKNKHDIEQFMRKVQYIN 586
            .|.|...|.|.|         :.||..:..| :|.  |...:.:.:..::...|.|.:|.|.|||
 Frog   523 MISCLQACKEGL---------DIKSLENLGQGVKYHFNPSQSALVMEGEDIESINQALRTVSYIN 578

  Fly   587 TKQKPTVGRRNIEVLTTLNCKNESS-LRLPPIETYIMV---NEP-IAPLGIDIDVVSASLETSDL 646
            ::|.||.|:|.::|.:.:.|..|.: :.:|.||.||||   ||| |...|:|.....|| |..:.
 Frog   579 SRQFPTAGKRRLKVSSKVQCFGEDTCITIPDIEAYIMVVQANEPKITVTGMDHFARPAS-EFENA 642

  Fly   647 TPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGKL---EEKNHIDSCSVVVFPS 708
            ......|.|.|:.|..|             :||....:|.|.|..:   |..:|:|.|.|:|
 Frog   643 NGVILLPDIRITSTVTK-------------MEKRLSKNVGKTNAPVVVEETLHHLDFCDVMV--- 691

  Fly   709 LNPDHEDIK---IDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNR 770
             :.:..|:|   ::.|.:......::...:..|..:.|..|:.:|.:||:.:.|.:...|....|
 Frog   692 -SGEELDVKKECLELDRTALQGKHLEATNSTKGYSIYGVGTMKSYEDVLQQIRYRHWDSASIFGR 755

  Fly   771 VFKLSCAQQSSQYKSGEYTLTLTVLHPKQTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVN 835
            .||:.|::.:.:|.|.|..|.:.:||                 ..||:.:.
 Frog   756 KFKVKCSELNGRYTSNELNLEVNILH-----------------NSNFMDHV-------------- 789

  Fly   836 GNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHK---AEGSHVTMLIILVSVFLAVLLCGVSI 897
                |.....:.:..||.|      |.:.:..  |:   :.|:...:|:..||:.:.:::.|:..
 Frog   790 ----NHMMIQQEFMPSLQH------PSTELSK--HETRVSPGATTIVLVACVSILVIIVVLGIFR 842

  Fly   898 ARLKNNQKYIEHHQPCPKISDDGLIWDDSALTITINPM---QADVTSDASSESENSESEDEE 956
            .|..:...:.|..    .:.||.|.|||||||||:|||   :...|::..||.|..|.|.||
 Frog   843 LRAVHQHDFQEKE----AVKDDELTWDDSALTITVNPMEKYETHGTNEGESEVEEEEEEIEE 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cals	NP_001259086.1	Cadherin_repeat	45..138	CDD:206637	39/112 (35%)
		Cadherin_repeat	147..238	CDD:206637	38/91 (42%)
		LamG	<435..527	CDD:304605	26/94 (28%)
clstn2	XP_002941239.2	Cadherin_repeat	36..144	CDD:206637	39/112 (35%)
		Cadherin_repeat	154..245	CDD:206637	38/90 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1633
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49698
Inparanoid	1	1.050	409	1.000	Inparanoid score	I1826
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D155997at33208
OrthoFinder	1	1.000	-	-		FOG0001333
OrthoInspector	1	1.000	-	-		otm49521
Panther	1	1.100	-	-	O	PTHR14139
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3174
SonicParanoid	1	1.000	-	-		X826
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190