Protein Alignment Arf4 and ARL2

DIOPT Version :10

• Sequence 1: NP_524631.1
• Gene: Arf4 / 43823
• FlyBaseID: FBgn0013749
• Length: 180
• Species: Drosophila melanogaster
• Sequence 2: NP_001658.2
• Gene: ARL2 / 402
• HGNCID: 693
• Length: 184
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 83/181 - (45%)
• Similarity: 125/181 - (69%)
• Gaps: 3/181 - (1%)

  Fly     1 MGLTISSLLTRLFGK-KQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFT 64
            |||.  ::|.::..| :::|:||:|||.|||||||.|....:|.|..||:|||::|:|::.....
Human     1 MGLL--TILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLN 63

  Fly    65 VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRITEAERELQNMLQEDELRDAVLLVFANKQD 129
            :||||||..:|..||:||::|.|||:||||.||.|:.:.:||||::|.|:.|..|.||:||||||
Human    64 IWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQD 128

  Fly   130 LPNAMTAAELTDKLRLNQLRNRHWFIQSTCATQGHGLYEGLDWLSAELAKK 180
            ||.|:::..:.:.|.|:.:|:.||.||...|..|..|..|:|||..:::.:
Human   129 LPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arf4	NP_524631.1	P-loop containing Nucleoside Triphosphate Hydrolases	1..180	CDD:476819	83/179 (46%)
ARL2	NP_001658.2	Arl2	3..175	CDD:206720	81/173 (47%)