DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11155 and GLR3.6

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001326369.1	Gene:	GLR3.6 / 824311	AraportID:	AT3G51480	Length:	903	Species:	Arabidopsis thaliana

Alignment Length:	917	Identity:	206/917 - (22%)
Similarity:	358/917 - (39%)	Gaps:	190/917 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ICCSYIILSILVISNALPPVIRVGAIFTEDERESS-IESAFKYAIYRINKEKTLLPNTQL---VY 83
            ||.:..:..:..|.:|.|.|:.:|::||.:..... |:.|...|:..:|...::|..|.|   ::
plant    10 ICNAVPLQGLTKIVSARPQVVNIGSVFTFNSLIGKVIKVAMDAAVEDVNASPSILNTTTLRIIMH 74

  Fly    84 DIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIE-GRIDLEYNSKE 147
            |.:|    :.|.:..:....:|:...||.||..:..|..|..:.....||.:. ...|...:..:
plant    75 DTKY----NGFMSIMEPLQFMESETVAIIGPQRSTTARVVAHVATELKIPILSFSATDPTMSPLQ 135

  Fly   148 FSINLYPSHTLL--TLAYRDIMVYLNWTKVAIIY-EEDY---GLFNLMHSSTETKAEMYIRQASP 206
            |...:..|...|  ..|..||:.:..|.:|..|| ::||   |:..|....:|.:..:..:.|.|
plant   136 FPFFIRTSQNDLFQMAAIADIVQFYGWREVVAIYGDDDYGRNGVAALGDRLSEKRCRISYKAALP 200

  Fly   207 -----DSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLED 266
                 ::...:|..:...|...|:|..:.......|.....|.|....|.::.|.: |.|
plant   201 PAPTRENITDLLIKVALSESRIIVVHASFIWGLELFNVARNLGMMSTGYVWIATNW-LST----- 259

  Fly   267 FRYNSVNITAFRLVDVDSKRYLEVINQMQ-----------------------KLQHNGLDTINGS 308
                        ::|.||...|:.||.:|                       .|.|.||.|.
plant   260 ------------IIDTDSPLPLDTINNIQGVITLRLHTPNSIMKQNFVQRWHNLTHVGLSTY--- 309

  Fly   309 PYIQTESALMFDSVYAFANGLHFL-----NLDNHQNFYIK-----NLSCTSDQTWNDGISLYNQI 363
                  :...:|:|:..|..:...     |:...:|..|.     ||...:.:.::.|......|
plant   310 ------ALYAYDTVWLLAQAIDDFFKKGGNVSFSKNPIISELGGGNLHLDALKVFDGGKIFLESI 368

  Fly   364 NAAITDGLTGTVQFVEGRRNIFK--LDILKLKQEKIQKVGYWHPDDGVNI-----SDPTAF---- 417
            ......||||.::|... ||:..  .|:|.:.......:|||....|:::     .:.|:|
plant   369 LQVDRIGLTGRMKFTSD-RNLVNPAFDVLNVIGTGYTTIGYWFNHSGLSVMPADEMENTSFSGQK 432

  Fly   418 ------------------YDSNIANITLVVMTR---EERPYVMVKEDKNLTGNLRFEGFCIDLLK 461
                              :.:|..::.:.|..|   ||  .|.||.:..:|      |||:|:..
plant   433 LHSVVWPGHSIKIPRGWVFSNNGRHLRIGVPNRYRFEE--VVSVKSNGMIT------GFCVDVFI 489

  Fly   462 AIATQVGFQYKIELV--------PDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARES 518
            |....:.:....|||        |.|...|.:..|..:            |..|..:||...|..
plant   490 AAINLLPYAVPFELVAFGNGHDNPSNSELVRLITTGVY------------DAGVGDITIITERTK 542

  Fly   519 VIDFTKPFMNLGIGILFKVPTSQPTR-----LFSFMNPLAIEIWLYVLAAYILVSFALFVMARFS 578
            :.|||:|::..|:.::      .|.|     ..:|:.|...::||...|::::|...::.:....
plant   543 MADFTQPYVESGLVVV------APVRKLGSSAMAFLRPFTPQMWLIAAASFLIVGAVIWCLEHKH 601

  Fly   579 PYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATST----RIVGGCWFFFCLI 639
            ..|::.|           .:..:..:|||...|..     .:.:.|:|    |||...|.|..||
plant   602 NDEFRGP-----------PRRQVITTFWFSFSTLF-----FSHRETTTSNLGRIVLIIWLFVVLI 650

  Fly   640 IISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRD---SKIGIYQKMWRY 701
            |.|||||:|.:.|||.::.|||:....| :......|..:|    :|.||   .::.|:  :.|.
plant   651 INSSYTASLTSILTVHQLSSPIKGIETL-QTNHDPIGYPQG----SFVRDYLIHELNIH--VSRL 708

  Fly   702 MENRKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSP 766
            :..|....:.|...||..:  .|..|.:.|...::..:...|....:|......|:|.|.|:.||
plant   709 VPLRSPEEYDKALRDGPGK--GGVAAVVDERAYIELFLSNRCEFGIVGQEFTKNGWGFAFPRNSP 771

  Fly   767 WRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLAL 831
            ....:|.|||:|.|.|.:|.:.|||...  ..|:.  :..|.:.:.|.:::..|:|||  ||:|.
plant   772 LAVDVSAAILQLSENGDMQRIRDKWLLR--KACSL--QGAEIEVDRLELKSFWGLFVV--CGVAC 830

  Fly   832 AVVVAIF 838
            .:.:|::
plant   831 VLALAVY 837

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	86/416 (21%)
		ANF_receptor	61..393	CDD:279440	78/381 (20%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	100/391 (26%)
		Lig_chan	555..829	CDD:278489	74/280 (26%)
GLR3.6	NP_001326369.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I1601
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	1	0.900	-	-		OOG6_100167
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870