DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11155 and grik5-like.1

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001072565.1	Gene:	grik5-like.1 / 780020	XenbaseID:	XB-GENE-5860197	Length:	479	Species:	Xenopus tropicalis

Alignment Length:	439	Identity:	171/439 - (38%)
Similarity:	251/439 - (57%)	Gaps:	23/439 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 LVVMTREERPYVMVKEDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSW 491
            |.|.|..|:|:.|..|.       ..||||||||..:|..:||.|.|:.|.|..||....:.| |
Frog    43 LTVTTIMEQPFSMKTES-------GMEGFCIDLLSELAQSLGFNYTIKEVKDGRYGAKDQDGN-W 99

  Fly   492 NGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF-KVPTSQPTRLFSFMNPLAIE 555
            ||:|.|::.:.||||||.:||..|||..:.||||||..||.||. |...|:.:.||.|:.|.:.|
Frog   100 NGMVGEVLRKEADLAVAPLTITGARERELAFTKPFMQTGISILLRKDDVSENSYLFGFLTPFSKE 164

  Fly   556 IWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLN 620
            .|:.:|.||::.|..||::.|.||.||       .|....:|.|:..||.||..|.|..||:..:
Frog   165 TWIGILVAYVVTSLCLFLVGRLSPCEW-------TELSTEQNNFNFLNSLWFGVGAFTLQGAEPH 222

  Fly   621 PKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERM-ISPIESASDLAEQTEISYGTLEGGSTM 684
            ||:.|.||:...|:.|.::::::|.|:.||||..:.| .:.|::..||..|..:.:||:...||.
Frog   223 PKSVSARIIAVIWWIFSIVLVAAYIASFAAFLNSDSMQTTNIQTFEDLVNQRTLEFGTINSSSTF 287

  Fly   685 TFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIG 749
            .||::||...|:.::.||:.||..:.||::.:|::||.|.:||||.||.|.|..|.:.|:|.:..
Frog   288 QFFKNSKNPTYRMIYEYMDKRKDELLVKSFAEGVRRVKESNYAFLGESVMQDIMVAKHCDLVRAP 352

  Fly   750 GLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALG 814
            .::..:|||||....||....:|:||||..|.|.|:.|..|||.||   ||   ..:.:..|.:.
Frog   353 QIIAGRGYGIAASLDSPLIKPLSVAILEQTESGNIEYLRKKWWDNT---CN---MKRSAGWNPVQ 411

  Fly   815 VENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEEL 863
            ...:||:|::|..||||.|:.|:.|....:|.|.:.:.:|.||..:||:
Frog   412 PHTLGGIFLILGIGLALGVIAALVELVLKARNNADQQKKSCCSAFSEEM 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377
		ANF_receptor	61..393	CDD:279440
		PBP2_iGluR_Kainate	424..793	CDD:270432	147/367 (40%)
		Lig_chan	555..829	CDD:278489	100/274 (36%)
grik5-like.1	NP_001072565.1	PBP2_iGluR_non_NMDA_like	41..396	CDD:270403	147/367 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010