Protein Alignment CG11155 and grin2ab

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_073805448.1
• Gene: grin2ab / 570493
• ZFINID: ZDB-GENE-070424-223
• Length: 1445
• Species: Danio rerio
• Alignment Length: 898
• Identity: 215/898 - (23%)
• Similarity: 373/898 - (41%)
• Gaps: 227/898 - (25%)

  Fly    91 DDSFRTTKKVCSQLEAGVQAI-FGPTDALLASHVQSICEAYDIPHIEGRI------------DLE 142
            :.:.|..:.:.:.|:..|.:| ...||.  .|.:..:||......:.|.:            .|:
Zfish    41 ESALRPARGIGAPLDVTVLSIQVNQTDP--GSMLTHLCELMSRQRLHGLVYGDGTDQEAVAQMLD 103

  Fly   143 YNSKEFSINLYPSH--TLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQAS 205
            :.|.:.|:.:...|  :.:|:|.:|                                       |
Zfish   104 FVSSQTSMPILGIHGGSAMTMAEKD---------------------------------------S 129

  Fly   206 PDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYN 270
            ..|:.|...:::|:.:..:.:                  |.::.:| :|:....:....::| ..
Zfish   130 SSSFFQFGASLQQEALLMLAI------------------MEEYDWH-VFSVVTTKFPGFQEF-IA 174

  Fly   271 SVNIT---AFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYI-----QTESALMFDSVYAFA- 326
            :|.:|   :|...|:.|...|:.:.:.:...|..|..|. ||.|     :.|:||:.:...:..
Zfish   175 TVRVTVDHSFVRWDLQSVVTLDGVGEPEDRAHVQLKRIQ-SPVILLYCSKDEAALVMEEARSLGL 238

  Fly   327 NGLHFL---------NLDN-HQNFYIKNLSCTSDQTWN--------DGISLYNQINAA------- 366
            .|..|:         ||:: .:.|....:|.|.|: |:        |.:.:.:...||
Zfish   239 TGAGFVWIVPSLTTGNLEHIPEAFPAGMISVTYDE-WDYPLETRLQDAVGIISSAAAAMFREEGR 302

  Fly   367 ITDGLTGTVQFVE-------------------GRRNIF---------KLDILKLKQEK-IQKVGY 402
            |.||........|                   |:.:.|         ||.::.|..|: .:|:|.
Zfish   303 IPDGTASCYGQSEKPEVPPSALRRYMMGVNLGGKDHSFMDDGYQVNPKLVVIVLNTEREWEKMGR 367

  Fly   403 WHPDDGVNISDP-----TAFYDSNIANITLVVMTREERPYVMVKEDKNLTGNLR----------- 451
            |. :..:.:..|     .:|.|.:.....|.::|.||||:|:|.:...|||...
Zfish   368 WE-NHSLRLKFPVWPRYNSFGDMDADENHLSIVTLEERPFVIVDDVDILTGTCMRNSVPCRKHIK 431

  Fly   452 ------------FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRAD 504
                        .:|||||:||.||..|.|.|.:.||.:..:|..|  .|.|||:|.|::.::|.
Zfish   432 DNTTEGSYVKKCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGKKI--NNVWNGMVGEVVYKKAV 494

  Fly   505 LAVASMTINYARESVIDFTKPFMNLGIGILFKVP--TSQPTRLFSFMNPLAIEIWLYVLAAYILV 567
            :||.|:|||..|...|||:.||:..||.::....  |..|:   :|:.|.:..:|:.:....::|
Zfish   495 MAVGSLTINEERSEAIDFSVPFVETGISVMVSRSNGTVSPS---AFLEPFSASVWVMMFVMLLIV 556

  Fly   568 -SFALFVMARFSPY-------EWKNPH-PCYKETDIVENQFSISNSFWFITGTFLRQGSGL-NPK 622
             :.|:|:....||.       :.|:|| |          .|:|..:.|.:.|........: ||:
Zfish   557 TAIAVFLFEFISPLGFNRNLAQGKDPHGP----------SFTIGKAVWLLWGLVFNNSVPVQNPR 611

  Fly   623 ATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISY------GTLEGG 681
            .|:::.:...|.||.:|.::|||||||||:..|..:..:...||...|:..||      ||:..|
Zfish   612 GTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDRKFQSPYSYSPPFRFGTVPNG 676

  Fly   682 STMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSY-AFLMESTMLDYAVQRD--C 743
            ||....|.:...::|.|.:|   .:|.|.     |.:..:..|.. ||:.::.:|:|...||  |
Zfish   677 STERNIRKNYPAMHQYMVKY---HQTGVV-----DALVSLKTGKLDAFIYDAAVLNYMAGRDDGC 733

  Fly   744 NLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSK 806
            .|..||.  :..:.|||||..|||.|:..:.||||.:...|.::.|..:|.  || :|:  ::..
Zfish   734 KLVTIGSGYIFATTGYGIAMQKGSYWKRLVDLAILGIIGDGEMEELEAQWL--TG-ICH--NEKN 793

  Fly   807 ESKANALGVENIGGVFVVLLCGLALAVVVAIFE--FCWNSRKNLNTENQSLCS 857
            |..::.|.|:|:.|||.:|...:||:::..::|  |.|..|....    .|||
Zfish   794 EVMSSQLDVDNMAGVFYMLAAAMALSLITFVWEHLFYWRLRYCFT----GLCS 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	65/399 (16%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	127/414 (31%)
		Lig_chan	554..828	CDD:459656	86/294 (29%)
grin2ab	XP_073805448.1	None