Protein Alignment CG11155 and grin3a

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_009303361.1
• Gene: grin3a / 564832
• ZFINID: ZDB-GENE-130530-780
• Length: 1111
• Species: Danio rerio
• Alignment Length: 1005
• Identity: 249/1005 - (24%)
• Similarity: 396/1005 - (39%)
• Gaps: 235/1005 - (23%)

  Fly    48 IFTEDERESSIESAFKYAIYRIN---KEKTLLPNTQLVYDIEYVPRDD---------------SF 94
            ||..|..|.......|.::..:|   |.||:|  .|:..|:.::|||.               .:
Zfish    87 IFQSDHEEDWRGIRTKSSVNNLNKASKSKTVL--KQVAPDVVFLPRDSVLLASESLNRVAGLLPY 149

  Fly    95 RTTKKVCSQLEAGVQAI----FG----PTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSIN 151
            ..|.::...:|||:..:    |.    |..|...|.:||:|....:..:...|....|..|
Zfish   150 NLTLEIVMAVEAGLGELPAFSFSSSSTPACADPVSFLQSVCHTVIVQGVSAIISFPQNRDE---- 210

  Fly   152 LYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLF-----NLMH------SSTETKAEMYIRQAS 205
                  |:.|.:  |...|....::::..|    |     ||:|      :...::|.:.....|
Zfish   211 ------LVKLEF--IASTLQIPVISVVQSE----FQRQTQNLLHFQMAMQNPQTSQANLIFSLLS 263

  Fly   206 PDSYRQV-LRAIRQKEIYKII----------------VDTNPSHIKSFFRSILQLQMNDHRYHYM 253
            .:::..| |...:|..|...:                :.||.|. |:.|...||.|:...:
Zfish   264 MNNWFDVSLVMCQQMNISDFVFLLHNNSKFHLGTVLKISTNSSS-KNDFHIFLQAQLESIK---- 323

  Fly   254 FTTFDLETY--DLEDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDT------INGSP- 309
            .:|..|.|:  |:.|.|.....|..|.|:..|....:.....:::|:..||..      ..|.|
Zfish   324 DSTSTLVTFGCDIRDIRRIFTTIAKFGLILPDYHWIIGDSQNVEELRTEGLPMGLLAHGRMGEPS 388

  Fly   310 ---YIQTESALMFDSVYAFA-------------NGLHFLNLDNHQNFYIKNLSCTSDQTWNDGIS 358
               |:|....|:..:|.:.|             |.|..|.        .|||:        .|..
Zfish   389 LDHYVQDALELVARAVGSAATVSPQLALIPGTTNCLARLE--------AKNLT--------SGTF 437

  Fly   359 LYNQINAAITDGLTGTVQFVEGRRNIFKLD--ILKLKQEKIQK-----VGYWH-----PDDGV-- 409
            |...:.:...|||:|.:...|....|.:..  |..|:.:.|.|     :|.|.     .|.||
Zfish   438 LSRYMASTSFDGLSGCISVQEESTIISESHHFIWNLQHDPIGKPMWTRLGSWKHGKVVMDYGVWP 502

  Fly   410 --NISDPTAFYDSNIANITLVVMTREERPYVMVK--EDKNL------------------------ 446
              ..|.|.|.: .:.:.:.|.|:|..|.|:|..:  :|:.|
Zfish   503 NKRRSQPGADW-RHSSRLHLRVVTLVEHPFVFTRDVDDEGLCPAGQLCLDPLTNDTALLESLFQG 566

  Fly   447 ------TGNLRFE----GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMER 501
                  |..|.|:    |:|||||:.:|..:||.:.:.:|.|..||.|  :...|.|:|.:||..
Zfish   567 LQGANDTVPLEFKKCCYGYCIDLLEKLAEDMGFDFDLYIVGDGKYGAY--KNGRWTGLVGDLMSG 629

  Fly   502 RADLAVASMTINYARESVIDFTKPFMNLGIGILFKV-PTSQPTRLFSFMNPLAIEIWLYVLAAYI 565
            .|.|||.|.:||.||..|||||.||.:..:|||.:. .|:.|  :.:||.||...:||.:..
Zfish   630 AAHLAVTSFSINSARSQVIDFTSPFFSTSLGILVRTRDTAAP--IGAFMWPLHWSMWLGIFV--- 689

  Fly   566 LVSFALFVMARF-SPYEWKNPH---PCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATST 626
                :|.|.|.| :.||||:|.   |..:..|.|.:..|..|..:.|  .|.|..:...||..:.
Zfish   690 ----SLHVTAVFLTLYEWKSPFGMTPRGRNRDRVFSFSSALNVCYAI--LFGRTAAIKPPKCWTG 748

  Fly   627 RIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASD--LAEQTE-ISYGTLEGGSTMTFFR 688
            |.:...|..|||..:|:|||||||.:..|:....:....|  |...:: ..:||:...|...:.:
Zfish   749 RFLMNLWAIFCLFCLSTYTANLAAVMVGEKTYEQLSGIHDPKLHHPSQGFRFGTVRESSAEDYVK 813

  Fly   689 DSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSY---AFLMESTMLDYAVQRDCNLTQIGG 750
            .|...:::.|.||.        ..|..|||..:.:...   ||:|:..:|||....|  ...|..
Zfish   814 KSFPEMHEYMRRYN--------APTTPDGIDHLKDDPQKLDAFIMDKALLDYWAHAD--KXYISL 868

  Fly   751 LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGV 815
            ||  .||||...:.||....||..:.:.:..|.:.:|:|||:|..  .|.:...: .::...:|:
Zfish   869 LL--TGYGIGLKQNSPLTSNISELVSQYKSDGFMDMLHDKWYKVV--PCGKRSFA-VTETLQMGI 928

  Fly   816 ENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRPRK 880
            ::..|:||:|..|:||:::..:.|         :..::.:...|.|........|.|:..||
Zfish   929 KHFSGLFVMLCVGVALSLLTTLGE---------HIVHRWVIPRMQESTEHKYWLHTSQRLHR--- 981

  Fly   881 RSCLNCSSVPTYVPSNVST-------SNVG 903
              .||    ||:....:.|       .|||
Zfish   982 --ALN----PTFKEDKLQTVAKPEKSCNVG 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	95/456 (21%)
		ANF_receptor	61..393	CDD:279440	83/412 (20%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	126/415 (30%)
		Lig_chan	555..829	CDD:278489	78/283 (28%)
grin3a	XP_009303361.1	Periplasmic_Binding_Protein_Type_1	36..502	CDD:299141	95/453 (21%)
		ANF_receptor	132..452	CDD:279440	68/356 (19%)
		PBP2_iGluR_NMDA_Nr3	518..908	CDD:270438	125/414 (30%)
		Lig_chan	682..941	CDD:278489	78/282 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591829
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740