Protein Alignment CG11155 and grin2aa

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_021329529.1
• Gene: grin2aa / 563297
• ZFINID: ZDB-GENE-070424-129
• Length: 1460
• Species: Danio rerio
• Alignment Length: 914
• Identity: 215/914 - (23%)
• Similarity: 367/914 - (40%)
• Gaps: 278/914 - (30%)

  Fly    46 GAIFTEDERESSIESAFKYAIYRINKEKTLLP-------NTQLVYDIEYVPRDDSFRTTKKVCSQ 103
            |.:|.:...:.:|.....:.     ..:||:|       ::.::.|          :..|....|
Zfish    94 GVVFGDGTDQEAIAQILDFI-----SSQTLIPILGIHGGSSMIMAD----------KDVKSTFFQ 143

  Fly   104 LEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSI--NLYPSHTLLTLAYRDI 166
            ..|.:|     .:|||   :.:|.|.||. |:            |||  :.:|       .|:|.
Zfish   144 FGASIQ-----QEALL---MLNIMEEYDW-HV------------FSIVTSKFP-------GYQDF 180

  Fly   167 MVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPS 231
            :..|..|     .:..:..::|.|..|       :.....||..|    |:.|::...:|
Zfish   181 IAILKTT-----VDNSFVGWDLQHIIT-------LDAVDGDSRTQ----IQLKKVQSPVV----- 224

  Fly   232 HIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDVDSKRYLEVINQMQK 296
                                .::.:.|...|.||:.|  |:.:|.|        .|:.::..:
Zfish   225 --------------------LLYCSKDEAAYILEEAR--SLGLTGF--------GYIWIVPSL-- 257

  Fly   297 LQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWN------- 354
                    ..|:|.|..::         |.:|:..::.|:                |:
Zfish   258 --------TTGNPEITPDT---------FPSGMISVSYDD----------------WDYPLEARV 289

  Fly   355 -DGISLYNQINAAIT------------------------------------DGLTGTVQFVEGRR 382
             ||:.:.....||:.                                    ||  ..:.|.|...
Zfish   290 RDGLGIITTAAAAMLEEFGDIPEAKTSCYGQMEKTKLPPSALHKYMMNVTWDG--KDLSFTEDGY 352

  Fly   383 NIF-KLDILKL-KQEKIQKVGYWHPDDGVNISDP-----TAFYDSNIANITLVVMTREERPYVMV 440
            .:. ||.::.| |..:.:|:|.|. :..:.:..|     .:|.|:...:..|.::|.||:|:|:|
Zfish   353 QVHPKLVVIVLNKDREWEKMGKWE-NQSLTLKYPVWPRFNSFGDAETDDNHLTIVTLEEKPFVIV 416

  Fly   441 KEDKNLTGNLR-------------------------FEGFCIDLLKAIATQVGFQYKIELVPDNM 480
            :..:.|||...                         .:|||||:||.||..|.|.|.:.||.:..
Zfish   417 ENVERLTGTCMRNSVPCRKHIKDNTTEGGGTYIKKCCKGFCIDILKKIARNVKFTYDLYLVTNGK 481

  Fly   481 YGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVP--TSQPT 543
            :|..|  .|.|||:|.|::.::|.:||.|:|||..|..||||:.||:..||.::....  |..|:
Zfish   482 HGKKI--NNVWNGMVGEVVNKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPS 544

  Fly   544 RLFSFMNPLAIEIWLYVLAAYILV-SFALFVMARFSPY-------EWKNPH-PCYKETDIVENQF 599
               :|:.|.:..:|:.:....:|| :.|:|:....||.       :.|:|| |          .|
Zfish   545 ---AFLEPFSASVWVMMFVMLLLVTAMAVFMFEYISPLGFNRNLAQGKDPHGP----------SF 596

  Fly   600 SISNSFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIES 663
            ::..:.|.:.|........: |||.|:::.:...|.||.:|.::|||||||||:..|..:..:..
Zfish   597 TMGKAVWLLWGLVFNNSVPVQNPKGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTG 661

  Fly   664 ASDLAEQTEISY------GTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVM 722
            .||...|:..||      ||:..|||....|.:    |..|.:||        ||.::.|:...:
Zfish   662 LSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKN----YPDMHQYM--------VKYHQTGVNDAL 714

  Fly   723 ----EGSY-AFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILEL 778
                .|.. ||:.::.:|:|...||  |.|..||.  :..:.|||||..|||.|:..:.||||.:
Zfish   715 VSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSLWKRPVDLAILAI 779

  Fly   779 QEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFE--FC 841
            ...|.::.|..:|.  || :|:  ::..|..::.|.|:|:.|||.:|...:.|:::..::|  |.
Zfish   780 IGDGEMEELEAQWL--TG-ICH--NEKNEVMSSQLDVDNMAGVFYMLATAMGLSLITFVWEHLFY 839

  Fly   842 WNSR 845
            |..|
Zfish   840 WRLR 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	67/418 (16%)
		ANF_receptor	61..393	CDD:279440	60/386 (16%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	129/420 (31%)
		Lig_chan	555..829	CDD:278489	88/298 (30%)
grin2aa	XP_021329529.1	PBP1_iGluR_NMDA_NR2	33..389	CDD:107373	68/426 (16%)
		PBP2_iGluR_NMDA_Nr2	400..799	CDD:270436	132/430 (31%)
		NMDAR2_C	836..1460	CDD:313729	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810