Protein Alignment CG11155 and KaiR1D

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_061498559.1
• Gene: KaiR1D / 4576020
• VectorBaseID: AGAMI1_006981
• Length: 930
• Species: Anopheles gambiae
• Alignment Length: 882
• Identity: 390/882 - (44%)
• Similarity: 546/882 - (61%)
• Gaps: 42/882 - (4%)

  Fly    24 CCSYIILSILVISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYV 88
            |...::|.....:.|||..||:|.:|..|:....|  ||:||:.:||.::|:||.::|:..||.:
Mosquito    14 CLLALLLHGPAPARALPDAIRIGGLFHPDDDHQEI--AFRYAVEKINSDRTILPRSKLLAQIERI 76

  Fly    89 PRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLY 153
            ...|||..:|:||..|..||.|||||..:..||||||||:..:|||:|.|.|.....:...:|||
Mosquito    77 SPQDSFLASKRVCHLLGVGVAAIFGPQSSHTASHVQSICDTMEIPHLETRWDYRLRRESCLVNLY 141

  Fly   154 PSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLF---NLMHSSTETKAEMYIRQASPDS--YRQVL 213
            |..:.|:.||.|::....|....||||.:.||.   .|:.:...:...:.:||.| ||  ||.:|
Mosquito   142 PHPSTLSKAYVDLVAAWGWKSFTIIYETNEGLVRMQELLKAHGLSDYPITVRQLS-DSGDYRPLL 205

  Fly   214 RAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFR 278
            :.|:......|::|.:...|....:...|:.|....:.|:.|:.||.|.:|::|:|...||||||
Mosquito   206 KQIKNSAESHIVLDCSTERIYEVLKQAQQIGMMSDYHSYLITSLDLHTINLDEFKYGGTNITAFR 270

  Fly   279 LVDVDSKRYLEVINQMQKLQHN------------GLDTINGSPYIQTESALMFDSVYAFANGLHF 331
            |||.::....:.|       ||            ...|......|:.|:|||:|:|:.||..||
Mosquito   271 LVDPENPEVAQAI-------HNWTIGEARLGKKVDFKTAENVTVIKAETALMYDAVHLFAKALH- 327

  Fly   332 LNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKLKQE 395
             :||..|...|..|||.:..||..|.||.|.:......|||..::| .:|.|:.|.|||::|..:
Mosquito   328 -DLDTSQQIDIHPLSCDTQDTWPHGYSLINYMKIVEMRGLTDVIKFDHQGFRSDFVLDIVELGPQ 391

  Fly   396 KIQKVGYWHPDDGVNISDPTAFYDSNIANI----TLVVMTREERPYVMVKED-KNLTGNLRFEGF 455
            .::|.|.|:...|||.:.........|..|    ||:|.|....||.|.|:. :.||||.:|||:
Mosquito   392 GLRKSGTWNSTSGVNFTRTYGEQQKEIVEILQNKTLIVTTILSAPYCMRKDSAEKLTGNSQFEGY 456

  Fly   456 CIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVI 520
            .|||:..|:..:||.|.|.|.||..||.:..||..|:|:::||:|:|||||:|.:||.:.||.|:
Mosquito   457 AIDLIHEISKILGFNYTIRLAPDGRYGSHNKETGEWDGMIKELLEQRADLAIADLTITFDREQVV 521

  Fly   521 DFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNP 585
            |||.|||||||.:|::.|..||..||||::||::::|:|:..||:.||..||::|||:||||..|
Mosquito   522 DFTMPFMNLGISVLYRKPVKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILARFTPYEWPTP 586

  Fly   586 HPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAA 650
            :||....:.::.||::.|..||..|:.::||....|||.|||:|.|.|:||.||:||||||||||
Mosquito   587 NPCDPHPEKLQTQFTLMNCMWFAIGSLMQQGCDFLPKAVSTRMVAGMWWFFTLIMISSYTANLAA 651

  Fly   651 FLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYE 715
            |||||||.||||||.|||:||:|.||.|.||||..|||||....||:||.:||:.:.:||..:..
Mosquito   652 FLTVERMDSPIESAEDLAKQTKIKYGALRGGSTAAFFRDSNFSTYQRMWSFMESARPSVFTASNI 716

  Fly   716 DGIKRVM--EGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILEL 778
            :|::||:  :||||||||||.::|.::|:|.|||:||:|||||||||.|..||:|..||.|:|:|
Mosquito   717 EGVERVVKGKGSYAFLMESTSIEYVIERNCELTQVGGMLDSKGYGIAMPPNSPFRTAISGAVLKL 781

  Fly   779 QEKGIIQILYDKWWKNT--GDVCNRDDKSKESK-ANALGVENIGGVFVVLLCGLALAVVVAIFEF 840
            ||:|.:.||..:|||..  |..| |||.||.|. ||.||:.|:|||||||:.|:.:|.|:|:.||
Mosquito   782 QEEGKLHILKTRWWKEKRGGGSC-RDDTSKSSSTANELGLANVGGVFVVLMGGMGVACVIAVCEF 845

  Fly   841 CWNSRKNLNTENQ-SLCSEMAEELRFAMHCHGSKSRH 876
            .|.|||....|.: |||||||.|||||:..:.::.:|
Mosquito   846 VWKSRKVAVEEREVSLCSEMASELRFALKRNRAQPKH 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	137/386 (35%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	200/375 (53%)
		Lig_chan	554..828	CDD:459656	155/278 (56%)
KaiR1D	XP_061498559.1	None