Protein Alignment CG11155 and grin2da

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 694
• Identity: 184/694 - (26%)
• Similarity: 293/694 - (42%)
• Gaps: 175/694 - (25%)

  Fly   323 YAFANGLHFLNLDNHQNFYIKNLSCTSDQTWND--------GISLYNQINAAIT---DGLTGT-- 374
            :|...||..|.|:.    ..|.|.....|.|.|        |:|:......|:.   .|..||
Zfish   306 FAVGPGLSGLGLEG----LPKALFAVRPQGWRDEPRRRIAKGVSVLTHGAMALRREYGGARGTSF 366

  Fly   375 ----------VQFVEGRRNIFK---------------------LDILKLKQEK-IQKVGYWHPDD 407
                      .|.|.||...|.                     ||::.....: .::||:|  ::
Zfish   367 AGNCMMDGNQTQRVPGRIRFFSNITLSGRDYSFNNDGYLANPLLDVISYTAGRGWEEVGWW--EN 429

  Fly   408 GV--NISDPTAFYDSNIANIT----LVVMTREERPYVMVKEDKNLTGN-LR-------------- 451
            ||  ....|.:.|...:..:.    |.|:|.||||:|:|:.....||: :|
Zfish   430 GVLRLRYPPWSRYGPFLKPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPCRLPLNNSMV 494

  Fly   452 ----------FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLA 506
                      .:|||||:||.:|..|||.|.:.||.:..:|..|  ...|||:|.|::.:|||:|
Zfish   495 VEGIQSMKHCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNI--DGQWNGMVGEVVSKRADMA 557

  Fly   507 VASMTINYARESVIDFTKPFMNLGIGILFKVP--TSQPTRLFSFMNPLAIEIWLYVLAAYI-LVS 568
            :.|:|||..|..|::|:.||:..||.::....  |..|:   :|:.|.:..:|:.:....: :|:
Zfish   558 IGSLTINEERSEVVEFSVPFVETGISVMVSRSNGTVSPS---AFLEPYSPAVWVMMFVMCLSVVA 619

  Fly   569 FALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGL-NPKATSTRIVGGC 632
            ..:|:...|||..:.......|...  .::|:|..|.|.:..........: ||:.|:::|:...
Zfish   620 VTVFIFEFFSPVGYNRSLQSGKTAG--GSKFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLV 682

  Fly   633 WFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQ--TE----ISYGTLEGGSTMTFFRDSK 691
            |.||.:|.::|||||||||:..|..|..:...||...|  ||    :.:||:..|||....|.:
Zfish   683 WAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLRFGTVPNGSTEENIRSN- 746

  Fly   692 IGIYQKMWRYM-ENRKTAVFVKTYEDGIKRVMEGSY-AFLMESTMLDYAVQRD--CNLTQIGG-- 750
               |..|.:|| .|.:..|     ||.|:.:..|.. ||:.::.:|:|..::|  |.:..||.
Zfish   747 ---YPNMHQYMVRNNQRGV-----EDAIENLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGK 803

  Fly   751 LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGV 815
            :..:.|||:|..|.|.|:..:.||:|:|.....|.:|...|   ...:|:.|  ..|..::.|.:
Zfish   804 VFATTGYGVALHKNSRWKRPLDLALLQLVGDDEIDMLERLW---LSGICHND--KIEVMSSKLDI 863

  Fly   816 ENIGGVFVVLLCGLALAVVVAIFEFC--WNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRP 878
            :|:.|||.:||..:.|:::|..:|..  |..|                      ||.|
Zfish   864 DNMAGVFYMLLVAMGLSLLVFAWEHLVYWKLR----------------------HCLG------- 899

  Fly   879 RKR-------------SCLNC----------SSVPTYVPSNVST 899
            |.|             ||.|.          |::|.|  .:|||
Zfish   900 RTRGLDFLLAFSRGMYSCCNFEDETAPGGSQSTLPQY--HHVST 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	28/133 (21%)
		ANF_receptor	61..393	CDD:279440	23/113 (20%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	125/413 (30%)
		Lig_chan	555..829	CDD:278489	83/287 (29%)
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	29/140 (21%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	126/417 (30%)
		HisJ	<507..>590	CDD:223904	36/84 (43%)
		Lig_chan	605..877	CDD:278489	83/287 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810