Protein Alignment CG11155 and GluRIB

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 1070
• Identity: 320/1070 - (29%)
• Similarity: 500/1070 - (46%)
• Gaps: 234/1070 - (21%)

  Fly    38 ALPPVIRVGAIFTEDERESSIESAFKYAI--YRINKEKTLLPNTQLVYDIEYVPRDDSFRTTKKV 100
            :|...|.:||||.:...|  ::||||||:  :.:|....   ..:|...::.:...|:|:.::.:
  Fly    37 SLTEKIPLGAIFEQGTDE--VQSAFKYAMLNHNLNVSSR---RFELQAYVDVINTADAFKLSRLI 96

  Fly   101 CSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHI------------EGRIDLEYNSKEFSINLY 153
            |:|...||.::.|.........:.|....:.:|.:            .|.:|       |::::.
  Fly    97 CNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLD-------FALSMR 154

  Fly   154 PSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNL------MHSSTETKAEMYIRQASPDS---- 208
            |.:   ..|..|.:.:..|.|:..:|:...||..|      :....|:.....:::.|..|
  Fly   155 PDY---HQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIE 216

  Fly   209 YRQVLRAIRQKEIYKIIVDTNPSHIKS-FFRSILQLQMNDHRYHYMFTTFDL-ETYDLEDFRYNS 271
            :...|..|.:.|...|::|......|. ..:.:..|::....|||:.:...: :.::.|...:.:
  Fly   217 FLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGA 281

  Fly   272 VNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYA------------ 324
            :|||.||:||.:.:...|..:..::|... :....|...|..::|||:|:|:.
  Fly   282 INITGFRIVDTNRRLVREFYDSWKRLDPQ-MSVGAGRESISAQAALMYDAVFVLVEAFNKILRKK 345

  Fly   325 ---FANGLH-------------------------------------FLNLDN--HQNFYIKNLSC 347
               |.|.:.                                     |...|:  ......:.|.|
  Fly   346 PDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDC 410

  Fly   348 TSDQTW------NDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKLK-QEKIQKVGYWH 404
            .:.:.|      .|.||.|  :.....:||||.::| .:|||..:.|.::::. ...:.||..|:
  Fly   411 NTAKGWVNAWEHGDKISRY--LRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWN 473

  Fly   405 PDDGVNISD-------PTAFYDSNIANITLVVMTREERPYVMVKE---DKNLTGNLRFEGFCIDL 459
            .|.|:...:       |...::.   |.|.:|.|..|.||:|:|:   .:.|.||.||||:|.||
  Fly   474 DDAGLQPLNAKYVRLRPHVEFEK---NRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDL 535

  Fly   460 LKAIATQVGFQYKIELVPDNMYGVYIPETNS----WNGIVQELMERRADLAVASMTINYARESVI 520
            ...:|.::|..|::.||.|..||   .|.:|    |:|:|.||:.:.||:|:|:|||...||.||
  Fly   536 ADLLAKELGINYELRLVKDGNYG---SEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVI 597

  Fly   521 DFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWK-- 583
            ||:||||:|||.|:.|.|..|...:|||||||:.|||:.|:.:||.||..||.::||||:||:
  Fly   598 DFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLV 662

  Fly   584 ----------NPHPCYKE----------------------------------------------- 591
                      :||..:::
  Fly   663 QQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSG 727

  Fly   592 --TDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTV 654
              :..|.|:||:.|||||....|::||..|:|::.|.||....||||.||:||||||||||||||
  Fly   728 GSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTV 792

  Fly   655 ERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIK 719
            |||::||.|..|||.|||:.||||..|||..|||.|:||::.|||.||.:|| .|||.||::|||
  Fly   793 ERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIK 856

  Fly   720 RV--MEGSYAFLMESTMLDYAVQRD-CNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEK 781
            ||  .:|.||.|:||...:|...|: |:..::|..||:||:|||||.||..:|.|:||:|.|:|.
  Fly   857 RVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKEN 921

  Fly   782 GIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRK 846
            |.:..|.:|||....: |: ..|..|:..:.|.:.|:.|:|.:|:.||.::|.|||.|:|:.||.
  Fly   922 GELIKLRNKWWYEKAE-CS-THKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRD 984

  Fly   847 -----------------------NLNTENQSL-------------CSEMAEELRFAMHCHGSKSR 875
                                   :|...|.|:             .|.....|...||.....:.
  Fly   985 SRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLGPSSAVPGGMPSSHQRSTLTDTMHAKAKLTI 1049

  Fly   876 HRPR-----KRSCLNCSSVPTYVPSNVSTS 900
            ...|     :...|||:|:..|.|:.:|.:
  Fly  1050 QASRDYDNGRVGYLNCASLQYYPPAQLSAT 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	89/453 (20%)
		ANF_receptor	61..393	CDD:279440	78/418 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	194/439 (44%)
		Lig_chan	555..829	CDD:278489	138/337 (41%)
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	88/452 (19%)
		ANF_receptor	55..461	CDD:279440	79/421 (19%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	195/445 (44%)
		Lig_chan	632..967	CDD:278489	138/337 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462570
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100167
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.740