Protein Alignment CG11155 and Ekar

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 900
• Identity: 484/900 - (53%)
• Similarity: 632/900 - (70%)
• Gaps: 48/900 - (5%)

  Fly    23 ICCSYIILSILVISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEY 87
            |...:::...|.....:||::|:||||:......:.|.||:|||:|:|.:|:|||.|.:.|.:||
  Fly     3 IASGFLLFQFLSYGLGVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEY 67

  Fly    88 VPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINL 152
            |.|.|||.|.:|||..:..||||:|.|||::||:|:.|||:|.|||:| ||     ::.:||||:
  Fly    68 VNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNI-GR-----SAHDFSINV 126

  Fly   153 YPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQASPDSYRQVLRAIR 217
            |||..|:..|:.|::.|||||:..|::|::.|:.||...|.....|:::||.|.|||...|...:
  Fly   127 YPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFK 191

  Fly   218 QKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDV 282
            .|||:.||:|||.:.|....::|||.|||:::|||:||:|||||||||||:||.||||:|||||.
  Fly   192 GKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDT 256

  Fly   283 DSKRYLEVINQMQKLQHNGLDTINGSPY----------IQTESALMFDSVYAFANGLHFLNLDNH 337
            ......:::..:....|:    |...||          :::|.||||||||.||.||.  .|:..
  Fly   257 ADVGVKQILKDIGLYSHH----IFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQ--TLEQS 315

  Fly   338 QNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRRNIFKLDILKLKQEKIQKVGY 402
            .:..:.|:||..:.:|:.|:||.|.:||....||||.:||.:|:|..||||::||||..|.|||.
  Fly   316 HSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGE 380

  Fly   403 WHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNLTGNLRFEGFCIDLLKAIATQV 467
            |.|...:||::|:.|:|:...|:||||:|..|.||||:...||.|||.||.|||:|:|:.|:.:|
  Fly   381 WTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREV 445

  Fly   468 GFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIG 532
            ||.|.::||||..||...|||..|||:|.:||:.:|||||.||||.||||||||||||||||||.
  Fly   446 GFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGIS 510

  Fly   533 ILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVEN 597
            ||||||||:||||||||||||||||:|||.||.|||..::::.:.||.|||..:.|..|...:.|
  Fly   511 ILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGN 575

  Fly   598 QFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIE 662
            |||:::||||..|||::|...:.|:|.||||:...|.||.|||::|||||||||||.||||:|||
  Fly   576 QFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIE 640

  Fly   663 SASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYA 727
            :|.|||.|||||||||:.||||||||||.|..|:|:||.|:|:|.:.|..|||||||||.:|:||
  Fly   641 NAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYA 705

  Fly   728 FLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWW 792
            ||||||||||.|||||||||||||||:||||||||||||||||||||||||||:|.||:||||||
  Fly   706 FLMESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWW 770

  Fly   793 KNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLN-TENQSLC 856
            |||.:.|.|.:.||:||||:||:|:||||||||:.|:.:|.|||.|||.:|.|.|.. |.:||:.
  Fly   771 KNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYNYEATPSQSVV 835

  Fly   857 S------------------------EMAEELRFAMHCHGSKSRHRPRKRSCLNCS 887
            :                        |:|||||:|..|. :|.:.....|:|..|:
  Fly   836 NNKYNQDGILESERNYTPPDRSFWIEIAEELRYASWCM-NKQKRPALTRTCSKCT 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	174/378 (46%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	254/368 (69%)
		Lig_chan	554..828	CDD:459656	187/273 (68%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	173/377 (46%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	254/368 (69%)
		Lig_chan	532..806	CDD:459656	187/273 (68%)