Protein Alignment CG11155 and gria4a

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 910
• Identity: 337/910 - (37%)
• Similarity: 495/910 - (54%)
• Gaps: 83/910 - (9%)

  Fly    30 LSILVI--------SNALPPVIRVGAIF---TEDERESSIESAFKYAIYRINKEKTLLPNT---- 79
            :.|||:        ..|.|..:::|.:|   |:.|     .:||:.||:..|..    ||.
Zfish     1 MRILVLIPLLWGLGEGAFPSSVQIGGLFIRNTDQE-----YTAFRLAIFLHNTS----PNATEAP 56

  Fly    80 -QLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEY 143
             .||..::.:...:||..|...|||...||.||||..|......:.|.|.|..|..:......|
Zfish    57 FNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLVTPSFPAE- 120

  Fly   144 NSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAE-------MYI 201
            ...:|.:.|.||   :..|...::.:.:|::...:|:.|.| :.::.:..|...:       :.:
Zfish   121 GETQFVLQLRPS---IRGALLSLLDHYDWSRFVFLYDTDRG-YAVLQAIMEKAGQNGWQVSAICV 181

  Fly   202 RQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLED 266
            ...:..|||::|..:.:::..|.::|.....:::....|:.:..:...|||:......:...||.
Zfish   182 ENFNDASYRRLLEDLDRRQEKKFVIDLEAERLQNILEQIVSVGKHVKGYHYIVANLGFKDISLER 246

  Fly   267 FRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHF 331
            |.:...|:|.|:|||......::::.:..||...........|  :..|:|.:|.|...|..  |
Zfish   247 FMHGGANVTGFQLVDFSKPMVIKLMQRWNKLDQREYPGSESPP--RYTSSLTYDGVLVMAEA--F 307

  Fly   332 LNLDNHQNFYIKNLSCTSD------QTWNDGISLYNQINAAITDGLTGTVQFVE-GRRNIFKLDI 389
            .|| ..|...|.......|      ..||.||.:...:......||||.:||.. |||..:.:|:
Zfish   308 RNL-RRQKIDISRRGNAGDCLANPAAPWNQGIDMERTLKQVRIQGLTGNIQFDHYGRRVNYTMDV 371

  Fly   390 LKLKQEKIQKVGYWHPDDGVNI--SDPTAFYDSNIANITLVVMTREERPYVMVKEDKNL-TGNLR 451
            .:||....:|:|||:..|.:.:  ::.:...||.:.|.|::|.|..|.||||:|::..: .||.:
Zfish   372 FELKSNGPRKIGYWNDLDKLVLVQNELSMGNDSAMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQ 436

  Fly   452 FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYAR 516
            |||:|:||...:|..:|.:|||.:|.|..||...|||..|||:|.||:..:|::|||.:.|...|
Zfish   437 FEGYCVDLASEVAKHIGIKYKISIVLDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLAITLVR 501

  Fly   517 ESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYE 581
            |.||||:||||:|||.|:.|.|......:|||::|||.|||:.::.|||.||..||:::||||||
Zfish   502 EEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 566

  Fly   582 WKNPHPCYKE------TDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLII 640
            |....|  :|      :|...|:|.|.||.||..|.|::||....|::.|.|||||.|:||.|||
Zfish   567 WHTEEP--EEGSDGPPSDQPPNEFGIFNSLWFSLGAFMQQGCDFTPRSLSGRIVGGVWWFFTLII 629

  Fly   641 ISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENR 705
            |||||||||||||||||:||||||.|||:||||:||||:.|||..|||.|||.:|:|||.||::.
Zfish   630 ISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSA 694

  Fly   706 KTAVFVKTYEDGIKRV--MEGSYAFLMESTMLDYAVQR-DCNLTQIGGLLDSKGYGIATPKGSPW 767
            :..||.||..:|:.||  .:|.||||:||||.:|..|| .|:..::||.|||||||:||||||..
Zfish   695 EPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQL 759

  Fly   768 RDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALA 832
            ...::||:|:|.|.|::..|.:|||.:.|:...:|..||:..:.||.:.|:.|||.:|:.||.||
Zfish   760 GTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKSSQALSLSNVAGVFYILVGGLGLA 824

  Fly   833 VVVAIFEFCWNSR---KNL---------NTENQSLCSEMAEELRF-------AMHCHGSKSRHRP 878
            ::||:.|||:.||   |.|         |....|:...:.|..|.       |:| .|...||.|
Zfish   825 MLVALVEFCYKSRAEAKKLKLTFSEAMRNKARLSITGSLGENGRVLTPDCPKAVH-SGPSYRHGP 888

  Fly   879  878
            Zfish   889  888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	95/392 (24%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	200/378 (53%)
		Lig_chan	554..828	CDD:459656	149/282 (53%)
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..395	CDD:380611	95/390 (24%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	202/383 (53%)