Protein Alignment CG11155 and Nmdar1

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 958
• Identity: 247/958 - (25%)
• Similarity: 416/958 - (43%)
• Gaps: 181/958 - (18%)

  Fly    40 PPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPR-----DDSFRTTKK 99
            |....:|.:.:..:.|....:..|:                |.:|.:||||     |.:.|..|.
  Fly    36 PSTYNIGGVLSNSDSEEHFSTTIKH----------------LNFDQQYVPRKVTYYDKTIRMDKN 84

  Fly   100 VCSQLEAGVQAIFGPTDALLASHVQSICEA-------------------YDIP--HIEGRIDLEY 143
                   .::.:|...|.|:.:.|.::..:                   |.||  .|..| |..:
  Fly    85 -------PIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSR-DAAF 141

  Fly   144 NSKEFSINL---YPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQAS 205
            :.|...::.   .|.:......:.:::.:..:|||.||:..|          |:.:|.:...|.:
  Fly   142 SDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSD----------TDGRAILGRFQTT 196

  Fly   206 PDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMF-TTFDLETYDLEDFRY 269
            ..:|..   .:..:...::||:..|. ::||...::.::....|.:.|: :|.|.:....:...|
  Fly   197 SQTYYD---DVDVRATVELIVEFEPK-LESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEY 257

  Fly   270 NSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESA-----LMFDSVYAFANGL 329
            |           :..:.::.::.:.....:|..|.:.|   :|.|.|     .:.||||..|:.:
  Fly   258 N-----------MTGEGHVWIVTEQALFSNNTPDGVLG---LQLEHAHSDKGHIRDSVYVLASAI 308

  Fly   330 HFLNLDNHQNFYIKNLSC-TSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRRNIFK-LDILKL 392
            .  .:.:::........| .|...|..|..|:..:.:....|.||.|.|.:....|:. .|::.:
  Fly   309 K--EMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINI 371

  Fly   393 K-QEKIQKVGYWHPDD-----GVNISDPTAFY--------DSNIANITLVVMTREERPYVMVK-- 441
            : |:|...||.:..|.     .:.|:|....:        :..:....|.::|.||:|:|.|:
  Fly   372 REQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRM 436

  Fly   442 -----------------EDKNLTGNLRF--EGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPE 487
                             .:.:.|.| .|  .|:|||||..::.::.|.|.:.|.||..:|.||..
  Fly   437 GDDEFRCEPDERPCPLFNNSDATAN-EFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILR 500

  Fly   488 TNS--------WNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTR 544
            .|:        |.|::.||:..|||:.||.:|||..|...|:|:|||...||.||.|.| |:.:.
  Fly   501 NNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKP-SRSST 564

  Fly   545 LFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPY-EWKNPHPCYKETDIVENQFSISNSFWFI 608
            |.||:.|.:..:|:.|:.:..:|:..|:::.||||: .:|..|....|    |...::|::.||.
  Fly   565 LVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNE----EKALNLSSAVWFA 625

  Fly   609 TGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVER---MISPIESASDLAE 669
            .|..|..|.|. .|::.|.|::|..|..|.:||::||||||||||.:||   .:|.|..|.....
  Fly   626 WGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNT 690

  Fly   670 QTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGS-YAFLMEST 733
            ...::..|::|.|...:|| .::.: ..|:|.||....|    |.|..|:.|.:|. .||:.:|:
  Fly   691 MENLTCATVKGSSVDMYFR-RQVEL-SNMYRTMEANNYA----TAEQAIQDVKKGKLMAFIWDSS 749

  Fly   734 MLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDV 798
            .|:|...:||.|...|.|....||||...|||||.|.::|||||..|.|.::.| ||.|...|.|
  Fly   750 RLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKL-DKQWIFHGHV 813

  Fly   799 ---CNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMA 860
               |...:|:    .|.||::|:.|||:::..|:|..|.:.|.|..:   |....:.|
  Fly   814 QQNCELFEKT----PNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIY---KKHQVKKQ------- 864

  Fly   861 EELRFAMHCHGSKSRHRPRKRSCLNCSSV----------PTYVPSNVS 898
            :.|..|.|. ..|.|....||..:..|..          .|:.|..:|
  Fly   865 KRLDIARHA-ADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTIS 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	73/408 (18%)
		ANF_receptor	61..393	CDD:279440	66/368 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	141/403 (35%)
		Lig_chan	555..829	CDD:278489	99/282 (35%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	76/422 (18%)
		ANF_receptor	58..371	CDD:279440	66/366 (18%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	144/413 (35%)
		HisJ	451..>558	CDD:223904	40/107 (37%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	50/139 (36%)
		Lig_chan	575..838	CDD:278489	99/277 (36%)
		CaM_bdg_C0	854..882	CDD:287524	7/38 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463113
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.940