Protein Alignment CG11155 and gria1b

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 923
• Identity: 337/923 - (36%)
• Similarity: 493/923 - (53%)
• Gaps: 85/923 - (9%)

  Fly    26 SYIILSI----LVISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIE 86
            |:::|..    |...::.|..|.:|.:|..|..|..:   |::|:.:.|....|:|      .::
Zfish     4 SFVLLLTGLLGLCSCSSFPSNINIGGLFPTDSHEYDV---FRFALSQHNDVPKLVP------QVD 59

  Fly    87 YVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSIN 151
            .|....||..|...|||...||.||.|..|....:.:.|.|.|..:..:.....::.|: :|.|.
Zfish    60 MVDTGSSFAMTYAFCSQFSKGVYAIIGLYDRKTMNMLMSFCGALHVCFVTPSFPIDTNN-QFVIQ 123

  Fly   152 LYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQASPD-------SY 209
            |.|.   |..|...::.:..|.|...:|..|.|| .::....:|.||...:..|.:       ::
Zfish   124 LRPE---LQDALIALVEHYKWNKFVYMYSSDSGL-TVLQKILDTAAEKTWQVTSINFDTLTEAAF 184

  Fly   210 RQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNI 274
            .:.::.:..|:.:|||:|.....:.|....|...:.|...|||:.........:|.:||....|:
Zfish   185 LKAIQDLDNKKEFKIILDCELERLNSILNLIAAQKKNLKNYHYILANLGFLDLNLTEFRKGGANV 249

  Fly   275 TAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQN 339
            |.|:|::..:......|...  |:.:..|..:....::...||.:|.|...|..  |.|| ..|.
Zfish   250 TGFQLMNYTNPTVSRTIQDW--LEFDSKDLKSPKRRLKYTGALTYDGVTVMATA--FQNL-RKQR 309

  Fly   340 FYIKNL----SCTSD--QTWNDGISLYNQINAAITDGLTGTVQFVE-GRRNIFKLDILKLKQEKI 397
            ..|...    .|.::  ..|..||.:...:.....:||||.|||.: |.|..|.:.:::......
Zfish   310 IDISRRGNAGECLANPPAPWGQGIDIQRALQQVQFEGLTGHVQFNDKGHRTNFTVSVMEFGPSGP 374

  Fly   398 QKVGYWHPDDGVNISDPTAFYDS------NIANITLVVMTREERPYVMVKED-KNLTGNLRFEGF 455
            :|||||:..:.. :|  ||.|.:      .:.|.|.||.|..|.||||:|:: :.|.||.::||:
Zfish   375 KKVGYWNQREKY-VS--TATYSNMLNETFGLQNRTYVVTTILEAPYVMLKKNHEQLVGNDKYEGY 436

  Fly   456 CIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVI 520
            |::|...||..||:.|::|||.|..||....||..|||:|.||:..:||:|||.:||...||.||
Zfish   437 CVELAAEIAKHVGYSYRLELVGDGKYGARDAETMMWNGMVGELVYGKADVAVAPLTITLVREEVI 501

  Fly   521 DFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEW--- 582
            ||:||||:|||.|:.|.||.....:|||::|||.|||:.::.|||.||..||:::|||||||
Zfish   502 DFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHAD 566

  Fly   583 ------------------KNPHPCYKETDIVE---------NQFSISNSFWFITGTFLRQGSGLN 620
                              .|..|...:....|         |:|.|.||.||..|.|::||..::
Zfish   567 DEEETADQQNQNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIFNSLWFSLGAFMQQGCDIS 631

  Fly   621 PKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMT 685
            |::.|.|||||.|:||.||||||||||||||||||||:||||||.|||:||||:||||:||||..
Zfish   632 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDGGSTKE 696

  Fly   686 FFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRV--MEGSYAFLMESTMLDYAVQR-DCNLTQ 747
            |||.|||.:::|||.||::.:..|||||.::|:.||  .:|.||:|:||||.:|..|| .|:..:
Zfish   697 FFRRSKIAVFEKMWSYMKSAEPTVFVKTTDEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMK 761

  Fly   748 IGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANA 812
            :||.|||||||:||||||..|:.::||:|:|.|:|::..|.:|||.:.|: |.......:.|.:|
Zfish   762 VGGNLDSKGYGVATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGE-CGSGGGDSKDKTSA 825

  Fly   813 LGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSR-- 875
            |.:.|:.|||.:|:.||.||::||:.|||:.||.......|.:.:.|.......|...|...|
Zfish   826 LSLSNVAGVFYILIGGLGLAMLVALVEFCYKSRIESRRMKQIIDAAMLSSTLTRMGSGGENGRVM 890

  Fly   876 -HR-PRKRSCLNC 886
             |. |:....|.|
Zfish   891 AHDFPKGAQTLPC 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	92/382 (24%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	205/402 (51%)
		Lig_chan	554..828	CDD:459656	149/306 (49%)
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..390	CDD:380613	93/385 (24%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	207/408 (51%)