DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11155 and Ir68a

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_648455.2	Gene:	Ir68a / 39269	FlyBaseID:	FBgn0036150	Length:	704	Species:	Drosophila melanogaster

Alignment Length:	725	Identity:	141/725 - (19%)
Similarity:	256/725 - (35%)	Gaps:	189/725 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 RQVLRAIRQKEIYKIIVDT--NPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSV 272
            :::|.....|..:.:|.|.  .|.:.:.||.|:         ...:...|.:.|.:.:|.:..|.
  Fly    42 QKILWVANVKRCFAVITDDLHYPIYDRIFFESV---------GRRVIPFFVMRTNESDDLQRPSR 97

  Fly   273 NITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNH 337
            .:..|......|...|.||..:     ||........||....:|.....:..   ||.|.|...
  Fly    98 QVELFVKAIKSSDCELNVITIL-----NGWQVQRFLGYIYDNRSLNMQKKFVL---LHDLRLFES 154

  Fly   338 QNFYIKNLSCTSDQTWN---DGISLYNQINAAITDGLTGTVQF---VEGRRNIFKLDILKLKQEK 396
            ...::          |:   |.|.|..|::...|   ..|:.|   :.|        :|.:|
  Fly   155 DMIHL----------WSVFIDAIFLKRQLDNKYT---ISTIAFPGILSG--------VLVMK--- 195

  Fly   397 IQKVGYWHPDDGVN----ISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNLTGNLRFEGFCI 457
              .:..|....|:|    .:|.|    ||:...:|.|...|..|.|:.   .|.|.:  |:|..:
  Fly   196 --NIANWELGKGLNGRILFADKT----SNLFGTSLPVAISEHVPMVLW---ANATKS--FQGVEV 249

  Fly   458 DLLKAIATQVGFQ---YKIELVPDNM------------YGVYIPETNSWNG------IVQELMER 501
            :::.|:...:.|:   ||.... :||            ||...|:..:.||      :|.|:...
  Fly   250 EIMNALGKALNFKPVYYKPNQT-ENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAH 313

  Fly   502 RADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLF-SFMNPLAIEIWLYVLAAYI 565
            .|..|:..:.:......:::.:.|. |... :.|..|.|.....: :|:.|.:..:|:.||.:..
  Fly   314 SARFAIGDLHLFQVYLKLVELSAPH-NFEC-LTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLF 376

  Fly   566 LVSFALFVMA---------------------RFSPYEWKNPHPCYKETDIVENQFSIS------- 602
            :|....:.::                     |..|.:.|    .|:.   :..:.:||
  Fly   377 VVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPK----IYRR---ISFRIAISRYRSSKG 434

  Fly   603 -----NSFWFITGTFLRQGSGL-------NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVE 655
                 :.|...|...|...|.|       .|:....|::.|.::.:|::::::|.|:..|.|...
  Fly   435 DRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANP 499

  Fly   656 RMISPIESASDLAEQTEISYGTLEGGST--MTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGI 718
            .....|::..||. ::.|...|   |:|  ..||.::...:.:|:...||       |..|.|.:
  Fly   500 AARVTIDTLEDLL-RSHIPPST---GATENRQFFLEANDEVARKVGEKME-------VFGYSDDL 553

  Fly   719 -KRVMEGSYAFLMESTMLDYA-----------VQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKI 771
             .|:.:|..|:......|.|.           :.::|.|..        ...:|..|.|..:.::
  Fly   554 TSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYM--------PVVLAMEKNSALKPRV 610

  Fly   772 SLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANAL-------GVENIGGVFVVLLCGL 829
            ..:|..|.|.|:|.    ||.|         |..:...|.||       .::.....||.||.|.
  Fly   611 DASIQHLAEGGLIA----KWLK---------DAIEHLPAEALAQQEALMNIQKFWSSFVALLIGY 662

  Fly   830 ALAVVVAIFE 839
            .::::..:.|
  Fly   663 VISMLTLLAE 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	39/207 (19%)
		ANF_receptor	61..393	CDD:279440	36/190 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	86/444 (19%)
		Lig_chan	555..829	CDD:278489	64/334 (19%)
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	54/263 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740