Protein Alignment CG11155 and GluRIIA

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 924
• Identity: 301/924 - (32%)
• Similarity: 471/924 - (50%)
• Gaps: 102/924 - (11%)

  Fly    25 CSYIILSILVISNALPPV----------IRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNT 79
            |..:|.:.::|...|..:          |.|||||.|:|:|  ||.:|..|...:|..|  ....
  Fly     4 CPVVIYAFIIIIGFLEGIIALGGDDRNEITVGAIFYENEKE--IELSFDQAFREVNNMK--FSEL 64

  Fly    80 QLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYN 144
            :.|....|:|.:|||...:..|..:..||.|||||:....:..|..|..|..|||||..:.||..
  Fly    65 RFVTIKRYMPTNDSFLLQQITCELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLKLEAT 129

  Fly   145 SKE-----FSINLYPSHTLLTLAYRDIM-VYLNWTKVAIIYEEDYGLF---NLMHSSTETKAEMY 200
            .:|     .|||:.||.::|:.||.:|: ....|....:|||...||.   :||:........:.
  Fly   130 RQEQLNHQMSINVAPSLSVLSRAYFEIIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVK 194

  Fly   201 IRQAS--PDSYRQVLRAIRQKEI------YKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTF 257
            :|..:  .|.||     |..||.      .:||:|..|..:|...:..:..::.....::..|..
  Fly   195 LRNLADYADDYR-----ILWKETDETFHEQRIILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHL 254

  Fly   258 DLETYDLEDFRYN---SVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTE-SALM 318
            |.....|.|. ||   ..|||:.||..||:..:     :.:|.:...:|.|.|:   ||. ..|:
  Fly   255 DTHNSGLRDI-YNEDFKANITSVRLKVVDANPF-----ERKKTRLTKVDQILGN---QTMLPILI 310

  Fly   319 FDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGL-----TGTVQFV 378
            :|:|..||:....: :...|.|:..|..|.|...|..|..:.|::.....|.:     |..::..
  Fly   311 YDAVVLFASSARNV-IAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMKLD 374

  Fly   379 E-GRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDPTAFYDSNIANITL--------------- 427
            | |:|..|.|:|.|....:...|  |.||:|:.         ..:.|:.|
  Fly   375 EYGQRIHFNLEIYKPTVNEPMMV--WTPDNGIK---------KRLLNLELESAGTTQDFSEQRKV 428

  Fly   428 -VVMTREERPYVMVKED-KNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNS 490
             .|:|..|.||.|:||| :|..|..::||:.:||:..::..:.|.|:..:|..|  |.|.|||..
  Fly   429 YTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGN--GKYNPETKQ 491

  Fly   491 WNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIE 555
            |:||:::|::..|.:.|..:||...|.||:|||.|||.|||.||......:|...|:|:.|.|:|
  Fly   492 WDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVE 556

  Fly   556 IWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLN 620
            :|:|::.|.::::.|...:||.|..||..|:|..::.|.:||.::::||.|.:.|:.::||..:.
  Fly   557 VWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDIL 621

  Fly   621 PKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMT 685
            |:....||:.|.|:||.|:::|:||||||||||..:..|.|:|..||.||.::.:|::.||||..
  Fly   622 PRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSL 686

  Fly   686 FFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVM--EGSYAFLMESTMLDYAVQRDCNLTQI 748
            ||.:|....||:.|..|::...:.|..|.::|:.||.  :|.||||||:|.|.|.::|:|:||||
  Fly   687 FFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCDLTQI 751

  Fly   749 GGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANAL 813
            |..:..|.||:|.|.||.:|..:|::||:|.|:|.:|.:.:|||||....|   |...|...:.|
  Fly   752 GEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTC---DSYHEVDGDEL 813

  Fly   814 GVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTEN-----QSLCSEMAEELRF-----AMH 868
            .:..:||||:||..|:.:.|::.||||.||. :|:..|.     |:..:|:...|:|     .|.
  Fly   814 SIIELGGVFLVLAGGVLIGVILGIFEFLWNV-QNVAVEERVTPWQAFKAELIFALKFWVRKKPMR 877

  Fly   869 CHGSKSRHRPRKRS 882
            ...|..:...|:.|
  Fly   878 ISSSSDKSSSRRSS 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	114/395 (29%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	151/387 (39%)
		Lig_chan	554..828	CDD:459656	111/275 (40%)
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	114/392 (29%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	149/371 (40%)
		Lig_chan	555..828	CDD:459656	111/275 (40%)