Protein Alignment CG11155 and gria4b

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 885
• Identity: 331/885 - (37%)
• Similarity: 494/885 - (55%)
• Gaps: 60/885 - (6%)

  Fly    22 KICCSYIILSILVI----SNALPPVIRVGAIF---TEDERESSIESAFKYAIYRINKEKTLLPNT 79
            :|.|:.::|....:    ..|.|..:::|.:|   |:.|     .:||:.||:..|..    ||.
Zfish     2 RISCNQLLLLFSCVWGLTMGAFPSSVQIGGLFIRNTDQE-----YTAFRLAIFLHNTS----PNA 57

  Fly    80 -----QLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRI 139
                 .||..::.:...:||..|...|||...||.||||..|......:.|.|.|..|..|....
Zfish    58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCGALHISLITPSF 122

  Fly   140 DLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAE------ 198
            ..|..| :|.:.|.||   :..|...::.:.:|.:...:|:.|.| ::::.:..|...:
Zfish   123 PTEGES-QFVLQLRPS---IRGALLSLLDHYDWNRFVFLYDTDRG-YSILQAIMEKAGQNGWQVS 182

  Fly   199 -MYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETY 262
             :.:...:..||||:|..:.:::....::|.....:.:....|:.:..:...|||:......:..
Zfish   183 AICVENFNDASYRQLLEDLDRRQEKTFVIDLEAERLNNMLEQIVSVGKHVKGYHYIMANLGFKDI 247

  Fly   263 DLEDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFAN 327
            :||.|.:...|:|.|:|||..:...::::.:..||........:..|  :..|||.:|.|...|.
Zfish   248 NLERFMHGGANVTGFQLVDFSNPMVIKLMQRWNKLDQREYPGSDAPP--KYTSALTYDGVMVMAE 310

  Fly   328 GLHFLNLDNHQNFYIKNLSCTSD------QTWNDGISLYNQINAAITDGLTGTVQFVE-GRRNIF 385
            .  |.|| ..|...|.......|      ..||.||.:...:......||||.|||.. |||..:
Zfish   311 A--FRNL-RRQKVDISRRGIAGDCLANPAAPWNQGIDMERTLKQVHLQGLTGNVQFDHYGRRVNY 372

  Fly   386 KLDILKLKQEKIQKVGYWHPDDGVNISDPTAFY---DSNIANITLVVMTREERPYVMVKEDKNL- 446
            .:|:.:||....:::|||:..|.:.::...|..   .|.:.|.|::|.|..|.||||:|::..:
Zfish   373 TMDVFELKSNGPRRIGYWNDADKLVLTQDHALLPNETSGMENRTVIVTTIMEGPYVMLKKNWEMY 437

  Fly   447 TGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMT 511
            .||.::||:|:||...||..:||:|||.:|||..||...|||..|||:|.||:..:|::|||.:|
Zfish   438 EGNEQYEGYCVDLASEIAKHIGFKYKISIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLT 502

  Fly   512 INYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMAR 576
            |...||.||||:||||:|||.|:.|.|......:|||::|||.|||:.::.|||.||..||:::|
Zfish   503 ITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR 567

  Fly   577 FSPYEWKNPHPCYKE------TDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFF 635
            ||||||....|  :|      :|...|:|.|.||.||..|.|::||..::|::.|.|||||.|:|
Zfish   568 FSPYEWHTEEP--EEGTDGLPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWF 630

  Fly   636 FCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWR 700
            |.||||||||||||||||||||:||||||.|||:||:|:||||:.|||..|||.|||.:|:|||.
Zfish   631 FTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTDIAYGTLDSGSTKEFFRRSKIAVYEKMWS 695

  Fly   701 YMENRKTAVFVKTYEDGIKRV--MEGSYAFLMESTMLDYAVQR-DCNLTQIGGLLDSKGYGIATP 762
            ||::.:..||.||..:|:.||  .:|.||||:||||.:|..|| .|:..::||.|||||||:|||
Zfish   696 YMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATP 760

  Fly   763 KGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLC 827
            |||..|..::||:|:|.|:|::..|.:|||.:.|:..:.....|:..:.||.:.|:.|||.:|:.
Zfish   761 KGSQLRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGGEKDKSSQALSLSNVAGVFYILVG 825

  Fly   828 GLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAM 867
            ||.||::||:.|||:.||........:....|..:.|.::
Zfish   826 GLGLAMLVALIEFCYKSRNEAKRMKLTFTEAMRNKARLSI 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	98/390 (25%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	203/378 (54%)
		Lig_chan	554..828	CDD:459656	147/282 (52%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_type1	28..400	CDD:471960	98/390 (25%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	204/380 (54%)
		Lig_chan	546..826	CDD:459656	147/281 (52%)