Protein Alignment CG11155 and GluRIIE

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 876
• Identity: 307/876 - (35%)
• Similarity: 471/876 - (53%)
• Gaps: 67/876 - (7%)

  Fly    52 DERESSIESAFKYAIYRINKE-KTLLPNTQLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPT 115
            |:....:...|.:||...|:| .|.|  |.|..::.|   .|::::..|:|..||.|:..:|||:
  Fly    46 DQNTEQMNIVFDHAIDVANQEVGTSL--TSLKEEVNY---GDAYQSYGKLCRMLETGIAGVFGPS 105

  Fly   116 DALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYE 180
            ....|.|:.|||:|.|||||...  :..|::.|  ||:|....|..|...::...|||:...:||
  Fly   106 SRHTAVHLMSICDAMDIPHIYSY--MSENAEGF--NLHPHPADLAKALYSLITEFNWTRFIFLYE 166

  Fly   181 --EDYGLFN-----LMHSSTETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFR 238
              |...:.|     |..|.|......|..|.: .:|:||||.:|:....:|:|..:...:..|..
  Fly   167 SAEYLNILNELTTMLGKSGTVITVLRYDMQLN-GNYKQVLRRVRKSVDNRIVVVGSSETMPEFLN 230

  Fly   239 SILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLD 303
            ...|:.:.:..|.|:....|..::|||:::|:..|||..||...:.....|::.::      |..
  Fly   231 QAQQVGIINEDYKYIIGNLDFHSFDLEEYKYSEANITGLRLFSPEKMAVKELLMKL------GYP 289

  Fly   304 T-----INGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIK----NLSCTSDQTWNDGISL 359
            |     .|||..|..|.||.:|:|..||..|        :|...|    |.|..::...:||.|.
  Fly   290 TDQDEFRNGSCPITVEMALTYDAVQLFAQTL--------KNLPFKPMPQNCSQRTESVRDDGSSF 346

  Fly   360 YNQINA-AITDG-LTGTVQFVEGRRNIFKLDILKLKQEKIQKVGYWHPDDGV---NISDPTAFYD 419
            .|.:.. .:||. |||.:.|....|..:.||:::|:...|.|||.|..|...   .::..||.:|
  Fly   347 KNYMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTTAQFD 411

  Fly   420 S---NIANIT-LVVMTREERPYV-MVKEDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDN 479
            |   ::||.| :::::...:||. :|:..|.|.||.::||:.:||:|.:|.::||.:.. :...|
  Fly   412 SVDNSLANKTFIILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDLIKELADKLGFNFTF-VNGGN 475

  Fly   480 MYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTR 544
            .||.|...||...|:::|:|..|||||:..:||...||..:|||.|||||||.||:..|......
  Fly   476 DYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPE 540

  Fly   545 LFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFIT 609
            ||:||:|.:.|:|.::..:::.||.:.|::.|.||.||.||:||.:|.:.:||||::.||.||.|
  Fly   541 LFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTT 605

  Fly   610 GTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTE-I 673
            |..|:|||.:.|||.|||.|...|:||.||::||||||||||||:|:..|.|.|..|||:..: :
  Fly   606 GALLQQGSEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGV 670

  Fly   674 SYGTLEGGSTMTFFRDSKIGIYQKMWRYM-ENRKTAVFVKTYEDGIKRVMEGS-YAFLMESTMLD 736
            .||..:.|||..||..|....|:||.::| ||.:  ...:...:|:.||...: ||||||||.::
  Fly   671 VYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQ--YLTEDNMEGVNRVKTNTHYAFLMESTSIE 733

  Fly   737 YAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTG-DVCN 800
            |..:|:|||.:||..||.||||||..|..|.|.|.:.|:|||||:|:::.:.:|||...| .:|.
  Fly   734 YNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWWNEVGTGICA 798

  Fly   801 RDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRF 865
            ..:.:.:  |..|.:.|:.|||.|||.|...|::..|..:.....|..:.....|...:.||.:|
  Fly   799 TKEDAPD--ATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHHYRVPLRDALKEEFQF 861

  Fly   866 AMHCH-------GSKSRHRPRKRSCLNCSSV 889
            .:..:       .|.|.:...::|.::.:||
  Fly   862 VIDFNNYVRVLKNSASIYSRSRQSSMSVASV 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	111/382 (29%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	166/373 (45%)
		Lig_chan	554..828	CDD:459656	125/277 (45%)
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	111/379 (29%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	166/373 (45%)
		Lig_chan	551..824	CDD:459656	125/276 (45%)