DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11155 and Ir7c

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	735	Identity:	141/735 - (19%)
Similarity:	257/735 - (34%)	Gaps:	191/735 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 VAIIYEEDYGLFNLMHSSTETKAEMYIRQASPDSYR-----------------QVLRAIRQKEIY 222
            |:::|...:.:.|....:|.|...:.....|.:|.|                 ::...:....:.
  Fly     9 VSLVYALVWAIDNYYGMATSTPLAVVQFPTSRESRRLHNDLIDAALGRSSGTGRIQFLLEDDRVE 73

  Fly   223 KIIVDTNP----------------SHIKSFFRSILQLQMNDHRYHYMFTTFDLETY-DLEDFRYN 270
            ....||:|                ..::|:||  |::.:|.....|....|.|..| .|||....
  Fly    74 MTETDTDPPPPSGLTGRPIAIWFLDSLRSYFR--LEMYLNQLGSPYKRNGFFLVIYTGLEDQPME 136

  Fly   271 SVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYI-----QTESAL-----MFDSVYAF 325
            |:.|...||::      :.|:|....||.:|  |::...|.     ..:|:|     .|..:.|.
  Fly   137 SLKIMFRRLLN------MYVLNVNVFLQRDG--TVHLYTYYPYGPHHCQSSLPVYYTAFQDLAAP 193

  Fly   326 ANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRRNIFKLDIL 390
            |||.                                        |||         :.:|...:
  Fly   194 ANGF----------------------------------------GLT---------KPLFPRKL- 208

  Fly   391 KLKQEKIQKVGYWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNLTGNLRFEGF 455
                                         :|:....:||.|.|.||||::::|....|.....|.
  Fly   209 -----------------------------TNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGI 244

  Fly   456 CIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVI 520
            ...:.:::|.::.|..|:....|...|..:|:.| :.||::.:::...:|.......:.||..::
  Fly   245 EGLIFRSLAERMNFTIKLVEQKDKNRGEILPDGN-FTGILKMMVDGEVNLTFVCFMYSKARSDLM 308

  Fly   521 DFTKPFMNLGIGILFK-----VPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPY 580
            ..:..:.:..|.::..     .|..:.||.|.::      ||..:|.: ::..|.|..:.:.:..
  Fly   309 LPSTSYTSFPIVLVVPSGGSISPMGRLTRPFRYI------IWSCILVS-LIFGFVLICLLKITAL 366

  Fly   581 EWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSY 644
                  |..:...:...........|    ..|..|..| ||:....|.:...|....||:.::|
  Fly   367 ------PGLRNLVLGRRNRLPFMGMW----ASLLGGLALYNPQRNFARYILVMWLLQTLILRAAY 421

  Fly   645 TANLAAFLTVERMISPIESASD-LAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTA 708
            |..|...|....|.|||:|.|: ||:..|  :..|.  :..|.|:||              ..|.
  Fly   422 TGQLYLLLQDVEMRSPIKSLSEVLAKDYE--FRILP--ALRTIFKDS--------------MPTT 468

  Fly   709 VF--VKTYEDGIKRVME----GSYAFLMESTMLDYAVQRDCN---LTQIGGLLDSKGYGIATPKG 764
            .|  |.:.|:.:.|:.:    |....|::.|:..:..:...|   ||.:...|.:..........
  Fly   469 NFHAVLSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPLMTAPLTFYMRPH 533

  Fly   765 SPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGL 829
            |.::.:|...|:.:...||:.    ::.|...|...|..|.:..:...|.:..:.|:| |...||
  Fly   534 SYFKRRIDRLIMAMMSSGIVA----RYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIF-VCCAGL 593

  Fly   830 AL-AVVVAIFEFCWNSRKNL 848
            .| |::|.|.|....:.:.|
  Fly   594 YLVALIVFILEILTTNHRRL 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	45/278 (16%)
		ANF_receptor	61..393	CDD:279440	45/261 (17%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	79/384 (21%)
		Lig_chan	555..829	CDD:278489	59/284 (21%)
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	15/62 (24%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	59/283 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740