Protein Alignment CG11155 and Nmdar2

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 889
• Identity: 197/889 - (22%)
• Similarity: 350/889 - (39%)
• Gaps: 200/889 - (22%)

  Fly   100 VCSQ-LEAGVQAI--------FGPTDALLASHVQSICEAYDIPHIEGRID---LEYNSKE--FSI 150
            :|.: |...|.||        ||.:.| .|.:...:.....||.|....|   ||..:.:  ..:
  Fly   167 LCKEFLRVNVSAILYMMNNEQFGHSTA-SAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQL 230

  Fly   151 NLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQASPDSYRQVLRA 215
            .|.||....:.|...|:....|.:.:::..:..|..:.:.:..|..|||
  Fly   231 QLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEM---------------- 279

  Fly   216 IRQKEIYKI-----IVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNIT 275
               :|.:|.     ||.|..|       .:::|..::.|...::.|             .:..||
  Fly   280 ---QEHFKFTILNSIVVTRTS-------DLMELVNSEARVMLLYAT-------------QTEAIT 321

  Fly   276 AFRLVD---VDSKRYLEVINQM---QKLQHNGLDTINGSPYIQTESALMFD------SVYAFANG 328
            ..|..:   :..:.|:.|::|.   :|..|:.........:..|.||.:.:      .:|::...
  Fly   322 ILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVE 386

  Fly   329 LHFLNLDNH-QNFYIKNLSCTSD--QTWNDGISLYNQI-NAAITDGLT-GTVQF-VEGRRNIFKL 387
            .:..:..|. :....::|||..:  ..|::|...:..: |.:|...|. ..::| .:|.....:|
  Fly   387 AYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAEL 451

  Fly   388 DILKLKQEKIQK------VGYWH--------------------PDDGVNISDPTAFYDSNIANIT 426
            .|:.|:.....|      :|.|.                    |..||    |..|:
  Fly   452 KIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGV----PEKFH-------- 504

  Fly   427 LVVMTREERPYVMVKEDKNLTGNLRFE---------------------------------GFCID 458
            |.:...||.||:.:.....::|....:                                 |||||
  Fly   505 LKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCID 569

  Fly   459 LLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFT 523
            ||:..|.::||.|::..|.|..:|..  |...|||::.:|:.|:.|:.:.|:.||..||:|:||:
  Fly   570 LLEKFAEELGFTYELVRVEDGKWGTL--ENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFS 632

  Fly   524 KPFMNLGIGILFKVPTS--QPTRLFSFMNPLAIEIWLYV-LAAYILVSFALFVMARFSPYEWKNP 585
            :|||..||.|:....|.  .||   :|:.|.....|:.| :.|....:|.:|:      :||.:|
  Fly   633 EPFMETGIAIVVAKRTGIISPT---AFLEPFDTASWMLVGIVAIQAATFMIFL------FEWLSP 688

  Fly   586 H----PCY-KETDIVENQFSISNSFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSY 644
            .    ..| :.|::...:||:..::|.:.....:....: :|:..::|.:...|..|.::.::.|
  Fly   689 SGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIY 753

  Fly   645 TANLAAFLTVERMISPIESASD------LAEQTEISYGTLEGGSTMTFFRDSKIGIY-QKMWRYM 702
            |||||||:............:|      .:.:....:||:....|     ||.|..| ..|..||
  Fly   754 TANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHT-----DSTIHKYFNVMHNYM 813

  Fly   703 -ENRKTAVFVKTYEDGIKRVMEGSY-AFLMESTMLDYAV--QRDCNLTQIGGLLDSKGYGIATPK 763
             :..||:|     .||:..|:.|:. :|:.:.|:|||.|  ..||.|..:|......|||:|..:
  Fly   814 RQYNKTSV-----ADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSR 873

  Fly   764 GSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCG 828
            .|.:....:..:||.:..|.::.|...|...|   | |..|.:...::.|.:|.....|::|:.|
  Fly   874 NSKYVQMFNKRLLEFRANGDLERLRRYWMTGT---C-RPGKQEHKSSDPLALEQFLSAFLLLMAG 934

  Fly   829 LALAVVVAIFEFCWNS--RKNLNTENQSLCS-----EMAEELRF 865
            :.||.::.:.|..:..  ||.|..::...|.     .|.:.|.|
  Fly   935 ILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTF 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	66/372 (18%)
		ANF_receptor	61..393	CDD:279440	60/329 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	109/421 (26%)
		Lig_chan	555..829	CDD:278489	71/291 (24%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	64/362 (18%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	112/438 (26%)
		Lig_chan	665..928	CDD:278489	69/282 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840