Protein Alignment CG11155 and GRIN2C

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 143/552 - (25%)
• Similarity: 247/552 - (44%)
• Gaps: 117/552 - (21%)

  Fly   389 ILKLKQEKI-QKVGYWHPDDGVNISDPTAF--YDSNIANIT----LVVMTREERPYVMVKEDKNL 446
            ::.|.:.:: :.||.|  :.||.......:  |.:::..:.    |.|.|.||||:|:|:.....
Human   435 VIALNRHRLWEMVGRW--EHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDPG 497

  Fly   447 TG--------------------------NLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYI 485
            ||                          .|..:|||||:||.:|..|.|.|.:.||.:..:|..:
Human   498 TGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGKRV 562

  Fly   486 PETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF--KVPTSQPTRLFSF 548
              ...|||::.|:..:|||:|:.|:|||..|..::||:.||:..||.::.  ...|..|:   :|
Human   563 --RGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPS---AF 622

  Fly   549 MNPLAIEIWLYVLAAYI-LVSFALFVMARFSPYEW--------KNPHPCYKETDIVENQFSISNS 604
            :.|.:..:|:.:....: :|:..:|:...|||..:        |:..|.          |:|..|
Human   623 LEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKSGGPA----------FTIGKS 677

  Fly   605 FWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDL- 667
            .|.:..........: ||:.|:::|:...|.||.:|.::|||||||||:..|:.|..:...||.
Human   678 VWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKK 742

  Fly   668 ---AEQTEIS-----------------------YGTLEGGSTMTFFRDSKIGIYQKMWRYMENRK 706
               .|.|.::                       :||:..|||....|.:...::..|.::.:
Human   743 SLHLENTGVAWTAFKTFCSDYFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQ--- 804

  Fly   707 TAVFVKTYEDGIKRVMEGSY---------AFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGYG 758
                 ::.||.:..:..||.         ||:.::.:|:|...:|  |.|..||.  :..:.|||
Human   805 -----RSVEDALTSLKMGSEAQPVPRKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYG 864

  Fly   759 IATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFV 823
            ||..|.|.|:..|.||:|:....|..|.|...|   ...:|  .::..|..::.|.::|:.|||.
Human   865 IAMQKDSHWKRAIDLALLQFLGDGETQKLETVW---LSGIC--QNEKNEVMSSKLDIDNMAGVFY 924

  Fly   824 VLLCGLALAVVVAIFEFC--WNSRKNLNTENQ 853
            :||..:.||::|..:|..  |..|.::...:|
Human   925 MLLVAMGLALLVFAWEHLVYWKLRHSVPNSSQ 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	5/21 (24%)
		ANF_receptor	61..393	CDD:279440	0/3 (0%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	120/450 (27%)
		Lig_chan	555..829	CDD:278489	80/323 (25%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740