Protein Alignment CG11155 and Grin2d

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_063136781.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1356
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 157/630 - (24%)
• Similarity: 268/630 - (42%)
• Gaps: 158/630 - (25%)

  Fly   330 HFLNL--DN-----HQNFYIKN-----LSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRR 382
            :|:|:  ||     :::.::.|     :|.|.|:||.                :.|:
  Rat   360 YFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWE----------------VVGS-------- 400

  Fly   383 NIFKLDILKLKQEKIQKVG-YWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNL 446
              ::...|:||.....:.| :..|.|...               .|.|.|.||||:|:|:....:
  Rat   401 --WEQQTLRLKYPLWSRYGRFLQPVDDTQ---------------HLTVATLEERPFVIVEPADPI 448

  Fly   447 TGN-LR--------------------------FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVY 484
            :|. :|                          .:|||||:||.:|..:||.|.:.||.:..:|..
  Rat   449 SGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKK 513

  Fly   485 IPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF--KVPTSQPTRLFS 547
            |  ...|||::.|:..:|||:|:.|:|||..|..::||:.||:..||.::.  ...|..|:   :
  Rat   514 I--DGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPS---A 573

  Fly   548 FMNPLAIEIWLYVLAAYI-LVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGT 611
            |:.|.:..:|:.:....: :|:..:|:....||..:.......|...  .:.|:|..|.|.:...
  Rat   574 FLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPG--GSTFTIGKSIWLLWAL 636

  Fly   612 FLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQ----- 670
            .......: ||:.|:::|:...|.||.:|.::|||||||||:..|..:..:...||...|
  Rat   637 VFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQ 701

  Fly   671 -TEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSY-AFLMEST 733
             ..:.:||:..|||....|.:...::..|.||.:.|        .|:.:.::..|.. ||:.::.
  Rat   702 YPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPR--------VEEALTQLKAGKLDAFIYDAA 758

  Fly   734 MLDYAVQRD--CNLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKN 794
            :|:|..::|  |.|..||.  :..:.|||||..|||.|:..|.||:|:......|::|...|
  Rat   759 VLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLW--- 820

  Fly   795 TGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFC--WNSRKNLNTENQSLCS 857
            ...:|:.|  ..|..::.|.::|:.|||.:||..:.|:::|..:|..  |..|
  Rat   821 LSGICHND--KIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLR------------ 871

  Fly   858 EMAEELRFAMHCHGSKSRHRPRKR------------SCLNCSSVP 890
                      ||.|      |..|            ||.:..:.|
  Rat   872 ----------HCLG------PTHRMDFLLAFSRGMYSCCSAEAAP 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	17/95 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	117/410 (29%)
		Lig_chan	554..828	CDD:459656	78/286 (27%)
Grin2d	XP_063136781.1	None