Protein Alignment CG11155 and Grin2d

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 638
• Identity: 157/638 - (24%)
• Similarity: 267/638 - (41%)
• Gaps: 163/638 - (25%)

  Fly   330 HFLNL--DN-----HQNFYIKN-----LSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRR 382
            :|:|:  ||     :::.::.|     :|.|.|:||.                :.|:
  Rat   360 YFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWE----------------VVGS-------- 400

  Fly   383 NIFKLDILKLKQEKIQKVG-YWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNL 446
              ::...|:||.....:.| :..|.|...               .|.|.|.||||:|:|:....:
  Rat   401 --WEQQTLRLKYPLWSRYGRFLQPVDDTQ---------------HLTVATLEERPFVIVEPADPI 448

  Fly   447 TGN-LR--------------------------FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVY 484
            :|. :|                          .:|||||:||.:|..:||.|.:.||.:..:|..
  Rat   449 SGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKK 513

  Fly   485 IPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF--KVPTSQPTRLFS 547
            |  ...|||::.|:..:|||:|:.|:|||..|..::||:.||:..||.::.  ...|..|:...:
  Rat   514 I--DGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLA 576

  Fly   548 FM--------NPLAIEIWLYVLAAYI-LVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISN 603
            |.        .|.:..:|:.:....: :|:..:|:....||..:.......|...  .:.|:|..
  Rat   577 FAWLTPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPG--GSTFTIGK 639

  Fly   604 SFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDL 667
            |.|.:..........: ||:.|:::|:...|.||.:|.::|||||||||:..|..:..:...||.
  Rat   640 SIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDR 704

  Fly   668 AEQ------TEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSY 726
            ..|      ..:.:||:..|||....|.:...::..|.||.:.|        .|:.:.::..|..
  Rat   705 KFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPR--------VEEALTQLKAGKL 761

  Fly   727 -AFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQI 786
             ||:.::.:|:|..::|  |.|..||.  :..:.|||||..|||.|:..|.||:|:......|::
  Rat   762 DAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEM 826

  Fly   787 LYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFC--WNSRKNLN 849
            |...|   ...:|:.|  ..|..::.|.::|:.|||.:||..:.|:::|..:|..  |..|
  Rat   827 LERLW---LSGICHND--KIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLR---- 882

  Fly   850 TENQSLCSEMAEELRFAMHCHGSKSRHRPRKR------------SCLNCSSVP 890
                              ||.|      |..|            ||.:..:.|
  Rat   883 ------------------HCLG------PTHRMDFLLAFSRGMYSCCSAEAAP 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	17/92 (18%)
		ANF_receptor	61..393	CDD:279440	12/74 (16%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	117/418 (28%)
		Lig_chan	555..829	CDD:278489	78/286 (27%)
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	13/75 (17%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	118/440 (27%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810