Protein Alignment CG11155 and Grik5

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 913
• Identity: 372/913 - (40%)
• Similarity: 535/913 - (58%)
• Gaps: 60/913 - (6%)

  Fly    29 ILSILVISNALPPV-----IRVGAIFTED------ERESSIESAFKYAIYRINKEKTLLPNTQLV 82
            :|.:|:::.|.|..     :|:.||..:.      ||     .|...|..:||....:....::.
  Rat     5 LLLLLIVAFANPSCQVLSSLRMAAILDDQTVCGRGER-----LALALAREQINGIIEVPAKARVE 64

  Fly    83 YDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDA-LLASHVQSICEAYDIPHI----EGRIDLE 142
            .||..:.||..:.||..:|..|..||.::.||:.: ..||.|..||...:||||    |....|:
  Rat    65 VDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQ 129

  Fly   143 YNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLF---NLMHSSTETKAEMYIRQA 204
            | .:..|::||||:..::||...|:...|:...::|..:...|.   .|:.....:|..:.:|..
  Rat   130 Y-LRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRML 193

  Fly   205 SPDSYRQ---VLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLED 266
              |..|.   :|:.||..::..||:|.|.|......|...:|.|....|.|:.||.|.....|:.
  Rat   194 --DDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHLDG 256

  Fly   267 FRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPY--IQTESALMFDSVYAFANGL 329
            ...:|.||..|.:.:.....|.|.:   :.|..:..:....|.|  ....:|||||:|:...:.:
  Rat   257 IVEDSSNILGFSMFNTSHPFYPEFV---RSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAV 318

  Fly   330 HFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKLK 393
            ..||  ..|...:|.|:|||...|..|.||.|.:.....|||||.|:| .:|:|..:.|.||:..
  Rat   319 RELN--RSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKS 381

  Fly   394 QEKIQKVGYWHPDDGVNISDPTAFYDSN----IANITLVVMTREERPYVMVKED-KNLTGNLRFE 453
            ::..:::|.|:.:..:.::..|  .|.|    :||.||||.|..|.||||.:.: :.|:||.|||
  Rat   382 RQGHREIGVWYSNRTLAMNATT--LDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFE 444

  Fly   454 GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN-SWNGIVQELMER-RADLAVASMTINYAR 516
            |||:|:|:.:|..:.|:|::.||.|.:||.  ||.| ||.|:|.||:.| :||||||:.||...|
  Rat   445 GFCVDMLRELAELLRFRYRLRLVEDGLYGA--PEPNGSWTGMVGELINRQKADLAVAAFTITAER 507

  Fly   517 ESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYE 581
            |.||||:||||.|||.||::|...:....|||::|.:..:||::|.||:.||..||:.||.||||
  Rat   508 EKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYE 572

  Fly   582 WKNPHPCYK-ETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYT 645
            |.|||||.: ...|:|||:::.||.||..|.|::|||.:.|:|.|||.|.|.|:.|.||||||||
  Rat   573 WYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYT 637

  Fly   646 ANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVF 710
            |||||||||:||..|:|||.|||:||.|.|||:..|||||||::|:...||:||.||::::.:||
  Rat   638 ANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVF 702

  Fly   711 VKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAI 775
            ||:.|:||.||:...||||:||||.:|..:.:|||||||||||:|||||..|.|||:||:|:|||
  Rat   703 VKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAI 767

  Fly   776 LELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEF 840
            |:|||...::||..|||:.     .|..|.::.:|..||:|||||:||||:|||.:||.||:.||
  Rat   768 LQLQENNRLEILKRKWWEG-----GRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEF 827

  Fly   841 CWNSRKNLNTENQSLCSEMAEELRFAMHCH-GSKSRHRPR----KRSCLNCSSVPTYVPSNVSTS 900
            .|::|::..:|..|:|.||.:|||.|:.|. .|:||.|.|    .|:.|:..:|.....||....
  Rat   828 IWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLY 892

  Fly   901 NVG 903
            :.|
  Rat   893 SAG 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	108/388 (28%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	209/372 (56%)
		Lig_chan	554..828	CDD:459656	156/274 (57%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	108/390 (28%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:473866	209/372 (56%)