Protein Alignment CG11155 and nmr-1

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_495033.2
• Gene: nmr-1 / 173929
• WormBaseID: WBGene00003774
• Length: 1025
• Species: Caenorhabditis elegans
• Alignment Length: 936
• Identity: 214/936 - (22%)
• Similarity: 381/936 - (40%)
• Gaps: 214/936 - (22%)

  Fly    30 LSILVISNALPPV-----IRVGAIFTEDERESS-------IESAFKYAIYRINKEKTLLPNTQLV 82
            :|:|::|......     :.|.|.|.|....:|       |.:||..|....|:       .:|.
 Worm    23 VSVLIVSEPNQETFKELKVSVTAAFVEVFGSTSYHLGNDTISAAFVDAKSGDNR-------LELT 80

  Fly    83 YDIEYVPRDDSFRTTKKVCSQL--EAGVQAIFGPTDALLASHVQSI---------CEAYDIPHIE 136
            .||              ||||:  .:....||.|   ||.|..:.|         ...|.:|.:.
 Worm    81 QDI--------------VCSQMLNHSLASVIFSP---LLTSSSRFIDLVTSSAYTLSFYKLPVVG 128

  Fly   137 GRI-DLEYNSKEFSINLYPS----------------HTLLTLAYRDIMVYLNWTKVAIIYEEDYG 184
            ..: |.|::.|    |:||:                |.||:|.||.::|
 Worm   129 VMVRDAEFSKK----NIYPTFVRPTAPLSDEAFVFLHMLLSLKYRQVVV---------------- 173

  Fly   185 LFNLMHSSTETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHR 249
                :....:..|:.::.:..           :::..:||||           :..:::::|::.
 Worm   174 ----LSVKRDINADQFVEEFE-----------KRRVEFKIIV-----------QRYIEVELNENL 212

  Fly   250 YHYMFTTFDLETYDL------EDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGS 308
            ...:..:|:..|.::      :|   ::|.|.| ...|:..|..:.::::.....||..:...|.
 Worm   213 NDTLAESFEEVTSNIIVLFAKKD---DAVRIFA-NAGDLTGKGKVWIVSESAGEAHNVPNGSLGC 273

  Fly   309 PYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQT---WN--DGISLYNQINAAIT 368
            ...||..:::.||.....:.:..:..::..:.: ..:.|..|..   ||  ...:|.|:|....|
 Worm   274 RLGQTAFSVLRDSFSILKSAMETIFRESKIDIF-PPVECDRDSVDAEWNSLQAPALLNEICGTST 337

  Fly   369 DGL------------TGTVQFVEGRRNIFKL--DILKLKQEKIQKVGYWHPDD--------GVNI 411
            ..:            ...:.|...|:.:..:  |||:|.::.|:..|...|.:        .|.:
 Worm   338 SRVHFNDKCERIGVEYDIINFHMERKQVGNMVGDILRLDEDSIEWAGGTKPLEISLPKHLRVVTV 402

  Fly   412 SDPTAFYDSNIAN--------ITLVVMTREER----------PYVMVKEDKNLTGNLRFEGFCID 458
            :||...|.:.|.:        .|:|..:..::          |..:    :|.|......|..||
 Worm   403 ADPPFVYTTPIGSPSQCAELGNTVVEWSIFDKIVVSGPWYSCPLTL----ENSTEYFCCAGLAID 463

  Fly   459 LLKAI-------ATQVGFQYKIELVPDNMYG-VYIPETN--SWNGIVQELMERRADLAVASMTIN 513
            ||..:       :....|.:.:.|  :..|| |...||.  :.:|::.||....||:|:..:|||
 Worm   464 LLSNLSLPEANNSIDTSFTFSLHL--NESYGVVQASETTGITISGVIGELDGDTADMAIGGITIN 526

  Fly   514 YARESVIDFTKPFMNLGIGILFK-VPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARF 577
            ..||.::|||:|::..||.||.| :|...|.:  ||:.||...:|..:..:.|||..|::.:...
 Worm   527 PERERIVDFTEPWLYHGIRILEKNIPRDSPMQ--SFLQPLQSSLWTALFISVILVGLAIYCLDFK 589

  Fly   578 SPYE------------WKNPHPCYKETDIVENQFSISNSFWFITGTFLRQG-SGLNPKATSTRIV 629
            ||:|            .|.....:...|..|| .:...:.||:.|..|..| |...|::.|.|::
 Worm   590 SPFERFYQADKEMEQDLKKEFELWIGKDADEN-VNFGEAMWFVWGVLLNSGVSEKTPRSCSARVL 653

  Fly   630 GGCWFFFCLIIISSYTANLAAFLTVERMISPIESASD---LAEQTEISYGTLEGGSTMTFF-RDS 690
            |..|..||:|:::||||||||||.:::....:...:|   .......|:||:...:...:| |..
 Worm   654 GIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTDPRLRNPSANFSFGTVLNSNVYQYFKRHV 718

  Fly   691 KIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSY-AFLMESTMLDYAVQRDCNLTQIGGLLDS 754
            ::   ..|:|.||...    |:...:.:..::.||. ||:.:||.|::...|.|.|...|.|...
 Worm   719 EL---SSMFRKMEPHN----VRRASEAVHSLLNGSLDAFIWDSTRLEFEAARHCELRTRGSLFGR 776

  Fly   755 KGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIG 819
            ..|||...|.|||...|:.|||.:.|.|:::.|..||....|..|..:.....::   ||:.|:.
 Worm   777 SAYGIGLQKNSPWTPHITSAILRMSESGVMEKLDQKWIDRGGPNCVVEAHKSPAR---LGLVNMK 838

  Fly   820 GVFVVLLCGLALAVVVAIFEFCWNSR 845
            .:|:::..|:||.:.::..|..:..|
 Worm   839 DIFILVSSGVALGIFLSFVEVSYGRR 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	78/436 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	118/415 (28%)
		Lig_chan	554..828	CDD:459656	81/291 (28%)
nmr-1	NP_495033.2	Periplasmic_Binding_Protein_type1	19..384	CDD:471960	78/435 (18%)
		PBP2_iGluR_NMDA_Nr1	394..822	CDD:270437	124/443 (28%)
		Lig_chan	566..844	CDD:459656	81/288 (28%)
		LITAF	949..1017	CDD:197841