Protein Alignment CG11155 and Grin3b

DIOPT Version :9

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_579842.2
• Gene: Grin3b / 170796
• RGDID: 621705
• Length: 1002
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 159/602 - (26%)
• Similarity: 262/602 - (43%)
• Gaps: 106/602 - (17%)

  Fly   312 QTE----SALMFDSVYAFANGLHFLNLDNHQNFYIKN-LSCTSDQTWND---GISLYNQINAAIT 368
            :||    .|::.|.|...|..|..:.|.:.:...:.. ::|...:|...   |.:|...:.....
  Rat   283 ETEQHSLEAVVHDMVELVAQALSSMALVHPERALLPAVVNCDDLKTGGSEATGRTLARFLGNTSF 347

  Fly   369 DGLTGTVQFVEGRRNI-----FKLDILKLKQEKI-----QKVGYWHPDDG----------VNISD 413
            .|.||.| :|.|...:     ||  :..|:::.:     ..||.|  .||          :.:..
  Rat   348 QGRTGAV-WVTGSSQVHVSRHFK--VWSLRRDPLGAPAWATVGSW--QDGQLDFQPGAAALRVPS 407

  Fly   414 PTAFYDSNIANITLVVMTREERPYVMVKE--------------DKNLTGNLRFE----------- 453
            |:    ...|...|.|:|..|.|:|..:|              |.....:.|.:
  Rat   408 PS----GTQARPKLRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSV 468

  Fly   454 ---------GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVAS 509
                     |:|||||:.:|..:.|.:::.:|.|..||..  ....|.|:|.:|:..||.:||.|
  Rat   469 PRTLRRCCYGYCIDLLERLAEDLAFDFELYIVGDGKYGAL--RDGRWTGLVGDLLAGRAHMAVTS 531

  Fly   510 MTINYARESVIDFTKPFMNLGIGILFKV-PTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFV 573
            .:||.||..|:|||.||.:..:||:.:. .|:.|  :.:||.||...:|:.|.||..|.  |||:
  Rat   532 FSINSARSQVVDFTSPFFSTSLGIMVRTRDTASP--IGAFMWPLHWSMWVGVFAALHLT--ALFL 592

  Fly   574 MARFSPYEWKNPH---PCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFF 635
                :.|||::|:   |..:....|.:..|..|..:.|  .|.|..|...||..:.|.:...|..
  Rat   593 ----TLYEWRSPYGLTPRGRNRGTVFSYSSALNLCYAI--LFGRTVSSKTPKCPTGRFLMNLWAI 651

  Fly   636 FCLIIISSYTANLAAFLTVERMISPIESASD--LAEQTE-ISYGTLEGGSTMTFFRDSKIGIYQK 697
            |||:::|||||||||.:..::....:....|  |...:: ..:||:...|...:.:.|    :.:
  Rat   652 FCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKAS----FPE 712

  Fly   698 MWRYMENRKTAVFVKTYEDGIKRVMEGS---YAFLMESTMLDY--AVQRDCNLTQIGGLLDSKGY 757
            |..:|....    ..|...|:..:....   .||:|:.::|||  ::..||.|..:|.....:||
  Rat   713 MHAHMRRHS----APTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGY 773

  Fly   758 GIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVF 822
            ||..|:.||....:|..|...:..|.|.:|:|||:|..  .|.: .....::...:||.:..|:|
  Rat   774 GIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMV--PCGK-RVFAVTETLQMGVYHFSGLF 835

  Fly   823 VVLLCGLALAVVVAIFE 839
            |:|..||..|::.::.|
  Rat   836 VLLCLGLGSALLTSLGE 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	26/125 (21%)
		ANF_receptor	61..393	CDD:279440	20/93 (22%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	119/414 (29%)
		Lig_chan	555..829	CDD:278489	79/284 (28%)
Grin3b	NP_579842.2	PBP1_iGluR_NMDA_NR3	21..405	CDD:107372	26/126 (21%)
		PBP2_iGluR_NMDA_Nr3	414..808	CDD:270438	118/413 (29%)
		Lig_chan	576..842	CDD:278489	79/284 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	882..910
		Involved in the trafficking and surface expression of NMDARs. /evidence=ECO:0000250	951..984

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840