Protein Alignment CG11155 and gria2a

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_005170953.1
• Gene: gria2a / 170450
• ZFINID: ZDB-GENE-020125-3
• Length: 893
• Species: Danio rerio
• Alignment Length: 865
• Identity: 319/865 - (36%)
• Similarity: 486/865 - (56%)
• Gaps: 68/865 - (7%)

  Fly    41 PVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTKKVCSQLE 105
            |.:::|.:|.....:       :|:.:||...:......:|...|:.:...:||..|...|||..
Zfish    20 PSVQIGGLFPRGADQ-------EYSAFRIGMVQFGTAEFRLTPHIDNLEVANSFAITNCFCSQFS 77

  Fly   106 AGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLYP--SHTLLTLAYRDIMV 168
            .||.||||..|....:.:.|.||...:..|......: ...:|.:.:.|  ...|::|     :.
Zfish    78 RGVYAIFGFYDKKSVNTITSFCETLHVSFITPSFPAD-GLNQFVLQMRPDIKGPLISL-----VE 136

  Fly   169 YLNWTKVAIIYEEDYGLFNL---MHSSTETKAEMYI-------RQASPDSYRQVLRAIRQKEIYK 223
            |..|.|.|.:|:.|.||..|   :.::.|.|.::..       .:...::||.:.:.:..|...:
Zfish   137 YYKWEKFAYLYDSDRGLSTLQAVLDTAAERKWQVTAINVGNLKDEWKDEAYRSLFQDLENKNERR 201

  Fly   224 IIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDVDS---K 285
            :|:|.....:|.....::.:..:...|||:...|.....||...:|...|::.|::||.|.   .
Zfish   202 VILDCEQDKVKDIMEQVITIGRHVKGYHYIIANFGFVDGDLSKIQYGGANVSGFQIVDFDDPLVA 266

  Fly   286 RYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYI----KNLS 346
            ::.:....:::.::.|.|:     .|:..|||.:|:|........||   :.|...|    .|..
Zfish   267 KFDQRWEALEEKEYPGADS-----RIRYTSALTYDAVQVMTEAFRFL---HKQRIDISRRGNNGD 323

  Fly   347 CTSDQT--WNDGISLYNQINAAITDGLTGTVQFVE-GRRNIFKLDILKLKQEKIQKVGYWHPDDG 408
            |.::..  |..|:.:...:.....|||||.:||.: |||..:.:::::||.....|:|||:..|.
Zfish   324 CLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGRRVNYTVNVMELKNSGPVKIGYWNEMDK 388

  Fly   409 VNISDPTAFYDSNIA--NITLVVMTREERPYVMVKEDKNL-TGNLRFEGFCIDLLKAIATQVGFQ 470
            :.::....|.:..:.  |.|::|.|..|.||||:|::..| |.|.|:||:|:||...||...||:
Zfish   389 MAVTKSDLFPNDTMGMENKTVIVTTILEAPYVMLKKNAELFTDNERYEGYCVDLAAEIAKHCGFK 453

  Fly   471 YKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF 535
            |::.:|.|..||....||..|||:|.||:..:||:|||.:||...||.||||:||||:|||.|:.
Zfish   454 YQLRIVADGKYGARDAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMI 518

  Fly   536 KVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVE---- 596
            |.|......:|||::|||.|||:.::.|||.||..||:::|||||||        .|:..|
Zfish   519 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW--------HTEEFEDGQL 575

  Fly   597 ------NQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVE 655
                  |:|.|.||.||..|.|::||..::|::.|.|||||.|:||.||||||||||||||||||
Zfish   576 GPSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVE 640

  Fly   656 RMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKR 720
            ||:||||||.|||:||||:||||:.|||..|||.|||.::.|||:||::.:.:||||...:|:.|
Zfish   641 RMVSPIESAEDLAKQTEIAYGTLDAGSTKEFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLR 705

  Fly   721 V--MEGSYAFLMESTMLDYAVQR-DCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKG 782
            |  .:|.||:|:||||.:|..|| .|:..::||.||||||||||||||..|:.::||:|:|.|:|
Zfish   706 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNAVNLAVLKLNEQG 770

  Fly   783 IIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKN 847
            ::..|.:|||.:.|:..:...:||| |.:||.:.|:.|||.:|:.||.||::||:.|||:.||..
Zfish   771 LLDKLKNKWWYDKGECGSGGGESKE-KTSALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAE 834

  Fly   848 LNTENQSLCSEMAEELRFAM 867
            ......:....|..:.|.::
Zfish   835 AKRMKMTFTDAMRSKARLSI 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	90/390 (23%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	201/382 (53%)
		Lig_chan	554..828	CDD:459656	149/286 (52%)
gria2a	XP_005170953.1	Periplasmic_Binding_Protein_type1	23..393	CDD:471960	90/390 (23%)
		PBP2_iGluR_AMPA	406..783	CDD:270433	202/384 (53%)