Protein Alignment CG11155 and Grin2d

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 644
• Identity: 159/644 - (24%)
• Similarity: 270/644 - (41%)
• Gaps: 169/644 - (26%)

  Fly   330 HFLNL--DN-----HQNFYIKN-----LSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRR 382
            :|:|:  ||     :::.::.|     :|.|.|:||.                :.|:
Mouse   365 YFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWE----------------VVGS-------- 405

  Fly   383 NIFKLDILKLKQEKIQKVG-YWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNL 446
              ::...|:||.....:.| :..|.|...               .|.|.|.||||:|:|:....:
Mouse   406 --WEQQTLRLKYPLWSRYGRFLQPVDDTQ---------------HLTVATLEERPFVIVEPADPI 453

  Fly   447 TGN-LR--------------------------------FEGFCIDLLKAIATQVGFQYKIELVPD 478
            :|. :|                                .:|||||:||.:|..:||.|.:.||.:
Mouse   454 SGTCIRDSVPCRSQLNRTHSLVAPRSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTN 518

  Fly   479 NMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF--KVPTSQ 541
            ..:|..|  ...|||::.|:..:|||:|:.|:|||..|..::||:.||:..||.::.  ...|..
Mouse   519 GKHGKKI--DGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVS 581

  Fly   542 PTRLFSF---MNPLAIE-----IWLYVLAAYI-LVSFALFVMARFSPYEWKNPHPCYKETDIVEN 597
            |:...:|   |.|::.|     :|:.:....: :|:..:|:....||..:.......|...  .:
Mouse   582 PSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPG--GS 644

  Fly   598 QFSISNSFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPI 661
            .|:|..|.|.:..........: ||:.|:::|:...|.||.:|.::|||||||||:..|..:..:
Mouse   645 TFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTV 709

  Fly   662 ESASDLAEQ------TEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKR 720
            ...||...|      ..:.:||:..|||....|.:...::..|.||.:.|        .|:.:.:
Mouse   710 SGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPR--------VEEALTQ 766

  Fly   721 VMEGSY-AFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILELQE 780
            :..|.. ||:.::.:|:|..::|  |.|..||.  :..:.|||||..|||.|:..|.||:|:...
Mouse   767 LKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLG 831

  Fly   781 KGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFC--WN 843
            ...|::|...|   ...:|:.|  ..|..::.|.::|:.|||.:||..:.|:::|..:|..  |.
Mouse   832 DDEIEMLERLW---LSGICHND--KIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWR 891

  Fly   844 SRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRPRKR------------SCLNCSSVP 890
            .|                      ||.|      |..|            ||.:..:.|
Mouse   892 LR----------------------HCLG------PTHRMDFLLAFSRGMYSCCSAEAAP 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	17/95 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	119/424 (28%)
		Lig_chan	554..828	CDD:459656	79/291 (27%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:471960	13/75 (17%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	120/446 (27%)