Protein Alignment CG11155 and Grin2c

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 525
• Identity: 145/525 - (27%)
• Similarity: 244/525 - (46%)
• Gaps: 86/525 - (16%)

  Fly   389 ILKLKQEKI-QKVGYWHPDDGVNISDPTAF--YDSNIANIT----LVVMTREERPYVMVKEDKNL 446
            ::.|.:.:: :.||.|  |.||.......:  |.:::..:.    |.|.|.||||:|:|:.....
Mouse   422 VIALNRHRLWEMVGRW--DHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPG 484

  Fly   447 TG--------------------------NLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYI 485
            ||                          .|..:|||||:||.:|..|.|.|.:.||.:..:|..:
Mouse   485 TGGCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRV 549

  Fly   486 PETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF--KVPTSQPTRLFSF 548
              ...|||::.|:..:|||:|:.|:|||..|..:|||:.||:..||.::.  ...|..|:   :|
Mouse   550 --RGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPS---AF 609

  Fly   549 MNPLAIEIWLYVLAAYI-LVSFALFVMARFSPYEW--------KNPHPCYKETDIVENQFSISNS 604
            :.|.:..:|:.:....: :|:..:|:...|||..:        |:..|          .|:|..|
Mouse   610 LEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGP----------SFTIGKS 664

  Fly   605 FWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLA 668
            .|.:..........: ||:.|:::|:...|.||.:|.::|||||||||:..|:.|..:...||..
Mouse   665 VWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKK 729

  Fly   669 EQ------TEISYGTLEGGSTMTFFRDSKIGIYQKMWRYM---ENRKTAVFVKTYEDGIKRVMEG 724
            .|      ....:||:..|||....|.:    |:.|..:|   ..|.....:.:.:.|.:.|...
Mouse   730 FQRPQDQYPPFRFGTVPNGSTERNIRSN----YRDMHTHMVKFNQRSVEDALTSLKMGARHVSRK 790

  Fly   725 SYAFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQ 785
            ..||:.::.:|:|...:|  |.|..||.  :..:.|||||..|.|.|:..|.||:|:....|..|
Mouse   791 LDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQ 855

  Fly   786 ILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFC--WNSRKNL 848
            .|...|   ...:|:  ::..|..::.|.::|:.|||.:||..:.||::|..:|..  |..|.::
Mouse   856 KLETVW---LSGICH--NEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSV 915

  Fly   849 NTENQ 853
            .:.:|
Mouse   916 PSSSQ 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	7/24 (29%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	121/423 (29%)
		Lig_chan	554..828	CDD:459656	80/296 (27%)
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	7/25 (28%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	122/429 (28%)
		NMDAR2_C	905..>980	CDD:463148	3/16 (19%)