Protein Alignment CG11155 and Ir25a

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_319463.5
• Gene: Ir25a / 1279695
• VectorBaseID: AGAMI1_004282
• Length: 946
• Species: Anopheles gambiae
• Alignment Length: 949
• Identity: 260/949 - (27%)
• Similarity: 427/949 - (44%)
• Gaps: 188/949 - (19%)

  Fly    16 GRSYLKKI---CCSYIILSILVISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLP 77
            ||.:|..|   ..||.|::|:..:..     .:..:|..:...:....|.:.|:..:.|.    |
Mosquito     6 GRRWLVLIPIQLASYAIIAIMGQTTQ-----NINILFVNEVDNNLANVAVEVALNYVKKN----P 61

  Fly    78 NTQLVYDIEYVP--RDDSFRTTKKVCSQLEAGVQAIFG-------PTDALL--------ASHVQS 125
            ...|..|:.||.  |.||....:.:||:        :|       |...||        :..|:|
Mosquito    62 QLGLSVDMMYVEGNRTDSKDLLQALCSK--------YGQSLSENRPPHLLLDTTLTGVSSETVKS 118

  Fly   126 ICEAYDIPHI------EGRI----DLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYE 180
            ...|..||.:      ||.:    ||....:.:.:.:.|...::....|.|::|:|.|..||:|:
Mosquito   119 FSLALGIPTVSASFGQEGDLRQWRDLTPTKRGYLLQVMPPADMIPQVIRSIIIYMNITNAAILYD 183

  Fly   181 EDYGLFNLMHSSTETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPS----------HIKS 235
               ..|.:.|                 .|:.:|:.|..:.:...|.|....          .|.:
Mosquito   184 ---NTFVMDH-----------------KYKALLQNIPTRHVITTIADDRDRASQIEKLRNLDINN 228

  Fly   236 FF--------RSILQLQMNDH-----RYHYMFTTFDLETYDLEDFRYNSVNITAFRL---VDVDS 284
            ||        :.:|:...|::     .:|.:       |.:.:|...|..|.|...|   .|..|
Mosquito   229 FFILGSLASIKQVLESAKNEYFERNFAWHVI-------TQEQKDLTCNVENATIMFLRPMSDSSS 286

  Fly   285 KRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSC-- 347
            |..|..|.....|:..  ..|.|..|..    |...::.|..|.|...:..::    :|.::|
Mosquito   287 KDRLGSIRTTYNLKQE--PQITGFFYFD----LTLRALIAIKNILQSGSWPSN----MKYITCED 341

  Fly   348 -TSDQTWNDGISL---YNQINAAITDG-----LTGTVQFVEGRRNIFKLDILKLK-----QEKIQ 398
             ....|.|..|.|   :.::....|.|     ..|.:||.......|.:||..:.     ....:
Mosquito   342 YDGTNTPNHTIDLKTAFIEVTEPTTFGPFEIPKGGKMQFNGNTYMKFDMDINAVSIRSGASVNTR 406

  Fly   399 KVGYWHP--DDGVNISDPTAFYDSNIANITLVVMTR----EERPYVMVKEDKNLTGNLRFEGFCI 457
            .:|.|..  :..:|:::     ::.|.|:|..|:.|    .:.|::|    ::.|....|:|:||
Mosquito   407 SLGTWEASLNAPINVAN-----EAEIKNLTADVVYRVYTVVQAPFIM----RDPTAPKGFKGYCI 462

  Fly   458 DLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDF 522
            |||..||..|.|.|:|..|.|..:| .:.|...|||||::|::::||:.:.||::...||:||||
Mosquito   463 DLLNKIAEIVEFDYEIREVEDGKFG-NMNENGEWNGIVRKLIDKQADIGLGSMSVMAERETVIDF 526

  Fly   523 TKPFMNL-GIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPH 586
            |.|:.:| ||.|:.::| |.|:.||.|:..|...:||.:||||...||.:::..|:|||.::|..
Mosquito   527 TVPYYDLVGISIMMQLP-STPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRYSPYSYQNNR 590

  Fly   587 PCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAF 651
            ..||..| .:.:|:|....||...:...||.|..||..|.|:|...|:.|..|||:|||||||||
Mosquito   591 EKYKNDD-EKREFNIKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAF 654

  Fly   652 LTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFR--------------------------DS 690
            |||.|:.:|:||..||::|.:|.|..|.|.|.||:|:                          .|
Mosquito   655 LTVSRLDTPVESLDDLSKQYKILYAPLNGSSAMTYFQRMADIEAKFYEIWKEMSLNDSLTAVERS 719

  Fly   691 KIGI--------YQKMWRYMENRKTAVFVKTYEDGIKRVMEGS----YAFLMESTMLDYAVQRDC 743
            |:.:        |.|||:.|   ..|....:.|:.::|:...:    :|||.::|.:.|.|..:|
Mosquito   720 KLAVWDYPVSDKYTKMWQAM---LEAGLPNSLEEAVQRIRNSTSASGFAFLGDATDIRYQVLTNC 781

  Fly   744 NLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKES 808
            :|..:|.....|.|.||..:|||.:|:.:.|||.|..:..::.|.::|||| .||.|:.:| .:.
Mosquito   782 DLQMVGEEFSRKPYAIAVQQGSPLKDQFNNAILMLLNRRELEKLKEQWWKN-DDVQNKCEK-PDD 844

  Fly   809 KANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKN 847
            :::.:.::||||||:|:..|:.:|.:..:|||.:...:|
Mosquito   845 QSDGISIQNIGGVFIVIFVGIGMACITLLFEFWYYKYRN 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	85/439 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	146/411 (36%)
		Lig_chan	554..828	CDD:459656	107/311 (34%)
Ir25a	XP_319463.5	None