Protein Alignment CG11155 and Nmdar2

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_061504088.1
• Gene: Nmdar2 / 1275196
• VectorBaseID: AGAMI1_003064
• Length: 910
• Species: Anopheles gambiae
• Alignment Length: 884
• Identity: 207/884 - (23%)
• Similarity: 351/884 - (39%)
• Gaps: 225/884 - (25%)

  Fly   132 IPHIEGRID---LEYNSKE--FSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHS 191
            ||.|....|   ||..:.:  ..:.|.||....:.|...|:....|.:.:::..:..|..:.:.:
Mosquito    26 IPVISWNADNSGLERRASQSALQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQA 90

  Fly   192 STETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTT 256
            ..|....|       |.::..        |...|:.|.||       .:|:|..::.|...::.|
Mosquito    91 VREQVGAM-------DHFKFT--------ILNSIIVTRPS-------DLLELVNSEARVMLLYCT 133

  Fly   257 FDLETYDLEDFRYNSVNIT-AFRLVDVDSKRYLEVINQ--MQKLQHN-----GL-----DTINGS 308
                       :..::.|. |...:.:..:.|:.|:.|  ::..|.:     |:     ||.:|:
Mosquito   134 -----------KSEAIEILHAAEELQITGENYVWVVTQSVIENTQTHPQFPIGMLGVHFDTSSGA 187

  Fly   309 PYIQTESALMFDSVYAFANGL-HFLN--------LDNHQNFYIKNLSCTSDQ---TWNDG----- 356
            ...:..:|:   .|||:  |: ::||        ||.||      ||| .||   .|:.|
Mosquito   188 LVNEIATAI---RVYAY--GVEYYLNDVKNTGRRLDTHQ------LSC-EDQGRGRWDSGEVFFK 240

  Fly   357 ----ISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKLKQEKIQK------VGYWH------ 404
                :||.::.|..       .::| .:|.....:|.|:.|:.....|      :|.|.
Mosquito   241 YLRNVSLESESNKP-------NIEFTADGDLKSAELKIMNLRPSVNSKGLVWEEIGIWKSWQQQK 298

  Fly   405 --------------PDDGVNISDPTAFYDSNIANITLVVMTREERPYV----------------- 438
                          |..||    |..|:        |.:...||.||:
Mosquito   299 LDIRDIAWPGNSHTPPQGV----PEKFH--------LKITFLEEAPYINLSPADPVSGKCLMDRG 351

  Fly   439 ---MVKEDKNLTG--------NLRF----EGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPET 488
               .|..|..:|.        |..|    .|||||||:..|.::||.|::..|.|..:|..  |.
Mosquito   352 VLCRVAADHEMTDIDMGQAHKNGSFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTL--EN 414

  Fly   489 NSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTS--QPTRLFSFMNP 551
            ..|||::.||:.|:.|:.:.|:.||..||:|:||::|||..||.|:....|.  .||   :|:.|
Mosquito   415 GKWNGLIHELVNRKTDMVLTSLMINAEREAVVDFSEPFMETGIAIVVAKRTGIISPT---AFLEP 476

  Fly   552 LAIEIWLYV-LAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVEN------QFSISNSFWFIT 609
            .....|:.| :.|....:|.:|:      :||.:|.. |....:::|      :||:..::|.:.
Mosquito   477 FDTASWMLVGIFAIQAATFMIFL------FEWLSPSG-YDMKTVLQNGQTTPYRFSLFRTYWLVW 534

  Fly   610 GTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASD------L 667
            ....:....: :|:..::|.:...|..|.::.::.||||||||:.............|      .
Mosquito   535 AVLFQAAVHVDSPRGFTSRFMTNVWAMFAVVFLAIYTANLAAFMITREEFHEFTGLDDSRLSHPF 599

  Fly   668 AEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYE-----DGIKRVMEGSY- 726
            :.:..|.:||:....|     ||.|..|.|...|        ::|.|.     ||:..|:.|..
Mosquito   600 SHKPTIKFGTIPWSHT-----DSTISKYFKEMHY--------YMKQYNRSSVADGVTAVLSGQLD 651

  Fly   727 AFLMESTMLDYAVQR--DCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYD 789
            ||:.:.|:|||.||:  ||.|..:|......|||:|..:.|.:....:..:||.:..|.::.|..
Mosquito   652 AFIYDGTVLDYLVQQDEDCRLLTVGQWYAMTGYGLAFSRNSKYVGMFNKRLLEFRANGDLERLRR 716

  Fly   790 KWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNS--RKNLNTEN 852
            .|...|   | |..|.:...::.|.:|.....|::|:.|:.||.::.:.|..:..  ||.|..::
Mosquito   717 FWMTGT---C-RPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHLYFKYFRKRLAKKD 777

  Fly   853 QSLCS-----EMAEELRFAMHCHGSKS---RHRPRKRSC 883
            :..|.     .|.:.|.|....:.:..   |||.....|
Mosquito   778 RGGCCALISLSMGKSLTFRGAVYEATEILRRHRCNDPIC 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	67/346 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	115/424 (27%)
		Lig_chan	554..828	CDD:459656	72/295 (24%)
Nmdar2	XP_061504088.1	None