Protein Alignment CG11155 and Grik4

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 887
• Identity: 357/887 - (40%)
• Similarity: 522/887 - (58%)
• Gaps: 55/887 - (6%)

  Fly    18 SYLKKICCSYIILSILVISNALPPVIRVGAIFTEDERESS--IESAFKYAIYRINKEKTLLPNTQ 80
            ::|..:.||             |..:|:.||. :|..|.|  ...:...|..|||:....|...:
Mouse    13 AWLLMVACS-------------PHSLRIAAIL-DDPMECSRGERLSITLAKNRINRAPERLGKAK 63

  Fly    81 LVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASH-VQSICEAYDIPHIEGRID--LE 142
            :..||..:.||..:.|.:.:|..|..||.|:.||:.:..:|. :.:||...::||.:...:  :.
Mouse    64 VEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVR 128

  Fly   143 YNSKEF-SINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFN---LMHSSTETKAEMYIRQ 203
            :..:.| ::||:||:|.:::|...|:.:.|.|...:|..:...|.|   |:.....:|..:.:|.
Mouse   129 FQLQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRM 193

  Fly   204 ASPDSYRQ---VLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLE 265
            .  |..|.   :|:.||..:...||:..|.|...:......:|.|....|.|:||..:.....::
Mouse   194 L--DDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMD 256

  Fly   266 DFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYI--QTESALMFDSVYAFANG 328
            ....:.|||..|.:.:.....:.|.   .|.|..:..:..:..|:.  ...|||:||:|||....
Mouse   257 SLVDDRVNILGFSIFNQSHAFFQEF---SQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTA 318

  Fly   329 LHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKL 392
            :..||  ..|...:|.|||.|.|.|..|.||.|.:.....:||||.::| .:|:|:.:.|.||:.
Mouse   319 VQELN--RSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQF 381

  Fly   393 KQEKIQKVGYWHPDDGVNISDPTAFYDSNIA----NITLVVMTREERPYVMVK-EDKNLTGNLRF 452
            .:...|::|.||..:|:::.  :..|.|||:    |.||||.|..|.||:|:| ..:.:.||.|:
Mouse   382 TRNGFQQIGQWHVAEGLSMD--SRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQEMEGNDRY 444

  Fly   453 EGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN-SWNGIVQELMERRADLAVASMTINYAR 516
            ||||:|:||.:|..:.|.|||.||.|.:|||  ||.| :|.|:|.||:.|:||||||.:||...|
Mouse   445 EGFCVDMLKELAEILRFNYKIRLVGDGVYGV--PEANGTWTGMVGELIARKADLAVAGLTITAER 507

  Fly   517 ESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYE 581
            |.||||:||||.|||.||::|...:....|||::|.:..:||::|.||:.||..||::||.:|||
Mouse   508 EKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYE 572

  Fly   582 WKNPHPCYK-ETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYT 645
            |.:||||.: ..:::.||:|:.||.||..|.|::|||.:.|:|.|||.|.|.|:.|.||||||||
Mouse   573 WYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYT 637

  Fly   646 ANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVF 710
            |||||||||:||..||||..|||:||.|.|||:.|||:||||::|:...||:||.||.:::.:||
Mouse   638 ANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVF 702

  Fly   711 VKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAI 775
            ||:.|:||.||:..:||||:||||.:|..||:|||||||||||:|||||..|.||.:||:..|||
Mouse   703 VKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAI 767

  Fly   776 LELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEF 840
            |:|||...::||..|||:  |..|   .|.::.:|..||:|||||:||||:|||.:|:.:|:.||
Mouse   768 LQLQENNRLEILKRKWWE--GGKC---PKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEF 827

  Fly   841 CWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRPRKRS 882
            .|..|.:..:| .|:|.||..|||..:.|  ..:.|..|:||
Mouse   828 LWTLRHSEASE-VSVCQEMVTELRNIILC--QDNIHPRRRRS 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	104/383 (27%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	207/371 (56%)
		Lig_chan	554..828	CDD:459656	154/274 (56%)
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:471960	104/387 (27%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	207/371 (56%)
		QRL_CxxC_CxxC	863..927	CDD:469521	3/4 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956