Protein Alignment CG11155 and grik5

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 901
• Identity: 373/901 - (41%)
• Similarity: 527/901 - (58%)
• Gaps: 63/901 - (6%)

  Fly    30 LSILVISNALPPV-----IRVGAIFTEDERESSIESAFKYAIYR--INKEKTLLPNTQLVYDIEY 87
            |.:|::|...|.|     :||.||. :|:...........|:.|  ||.......:.::..:|..
 Frog    10 LLLLLLSFTSPGVSLLSSLRVAAIL-DDQTVCGRGERLALALAREHINSHTQGSASGRVEVEIFE 73

  Fly    88 VPRDDSFRTTKKVCSQLEAGVQAIFGP-TDALLASHVQSICEAYDIPHI----EGRIDLEYNSKE 147
            :.:|..:.||..:|..|..||.::.|| |....||.|..||...:||||    |....|:| .:.
 Frog    74 LQKDSQYETTDTMCQILPKGVVSVLGPSTSPASASTVSHICGEKEIPHIKVGPEEAPKLQY-LRF 137

  Fly   148 FSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQ--ASPD--S 208
            .|::||||:..::||...|:...:....::|..:...|..|         |..:||  .|.|  |
 Frog   138 ASVSLYPSNEDISLAVSHILKSFHNPSTSLICAKAECLLRL---------EELVRQFLISKDTLS 193

  Fly   209 YRQ---------VLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDL 264
            .|.         :|:.||..::..||:|.|.:......:...:|.|....|.|:.||.|.....|
 Frog   194 VRMLDESNDPTPLLKEIRDDKVSTIIIDANATVSHLILKKASELGMTSAHYKYILTTMDFPLLSL 258

  Fly   265 EDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYI--QTESALMFDSVYAFAN 327
            |....:..||..|.:.:.....|||.   ::.|..:..:....|.|:  ...:|||||:|:...:
 Frog   259 EGIVSDQSNILGFSMYNSSHPFYLEF---LRSLNMSWRENCELSTYLGPALSAALMFDAVHVVVS 320

  Fly   328 GLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILK 391
            .:..||  ..|...:|.|||::.|.|..|.||.|.:.....|||||.|:| .:|:|..:.|.||:
 Frog   321 AVRELN--RSQEIGVKQLSCSTSQIWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILE 383

  Fly   392 LKQEKIQKVGYWHPDD--GVNISDPTAFYDSNIANITLVVMTREERPYVMVKED-KNLTGNLRFE 453
            ...:..:::|.|:.:.  .:|.:.........:.|.||||.|..|.||:|.|.: ::|:||.::|
 Frog   384 KAGDGHREIGVWYSNRTLAMNATSLDLSTSETLENKTLVVTTILENPYMMRKSNYRSLSGNDQYE 448

  Fly   454 GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN-SWNGIVQELMERRADLAVASMTINYARE 517
            |||.::|..:|..:.|.|||:||.|.:||.  ||.| ||.|:|.||:.|:||||||:.||...||
 Frog   449 GFCAEMLMELAALLRFNYKIKLVEDGLYGA--PEPNGSWTGMVGELINRKADLAVAAFTITAERE 511

  Fly   518 SVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEW 582
            .||||:||||.|||.||::|...:....|||::|.:..:||::|.||:.||..||:.||.|||||
 Frog   512 KVIDFSKPFMTLGISILYRVQMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEW 576

  Fly   583 KNPHPCYKET-DIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTA 646
            .|||||.:|. .|:|||:::.||.||..|.|::|||.:.|:|.|||.|.|.|:.|.|||||||||
 Frog   577 YNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCVSGVWWAFTLIIISSYTA 641

  Fly   647 NLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFV 711
            ||||||||:||..|||||.|||:||.|.|||:.||||||||::|:...||:||.||.:::.:|||
 Frog   642 NLAAFLTVQRMEVPIESADDLADQTNIEYGTIHGGSTMTFFQNSRYQTYQRMWNYMNSKQPSVFV 706

  Fly   712 KTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAIL 776
            |:.|:||.||:...||||:||||.:|..:.:|||||||||||:|||||..|.|||:||:|:||||
 Frog   707 KSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPYRDEITLAIL 771

  Fly   777 ELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFC 841
            :|||...::||..|||:  |..|   .|.::.:|..||:|||||:||||:|||.:||.|||.||.
 Frog   772 QLQENNRLEILKRKWWE--GGKC---PKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAIMEFV 831

  Fly   842 WNSRKNLNTENQSLCSEMAEELRFAMHC-HGSKSRHRPRK------RSCLNCSSVP 890
            |::|::::.|..|:|.||..|||.|:.| ..|:||||.|.      |:.|:.|..|
 Frog   832 WSTRRSVDNEEISVCQEMLSELRSAVSCKKTSRSRHRRRPPRHLHGRTLLSLSRPP 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	109/393 (28%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	211/371 (57%)
		Lig_chan	554..828	CDD:459656	160/274 (58%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	108/393 (27%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	211/371 (57%)