Protein Alignment CG11155 and grik2

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_017949808.1
• Gene: grik2 / 100495093
• XenbaseID: XB-GENE-5902331
• Length: 913
• Species: Xenopus tropicalis
• Alignment Length: 862
• Identity: 390/862 - (45%)
• Similarity: 564/862 - (65%)
• Gaps: 40/862 - (4%)

  Fly    42 VIRVGAIF--TEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTKKVCSQL 104
            |:|.|.||  .|.....:.|.||::|:..||:.:||||||.|.||.:.:...|||..::|.|.||
 Frog    40 VLRFGGIFEYVESGPFGAEELAFRFAVNTINRNRTLLPNTTLTYDTQRINLYDSFEASRKACEQL 104

  Fly   105 EAGVQAIFGPTDALLASHVQSICEAYDIPHIEGR--IDLEYNSKEFSINLYPSHTLLTLAYRDIM 167
            ..||.|||||:.:..|:.|||||.|..:|||:.|  ..:..|...|.::|||..:.|:.|..|::
 Frog   105 SLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV 169

  Fly   168 VYLNWTKVAIIYEEDYGLF---NLMHSSTETKAEMYIRQASPDS--YRQVLRAIRQKEIYKIIVD 227
            .:..|..|.|.|::..||.   .|:.:.:.....:.|||...|:  .:.:|:.:::.:.:.:|.|
 Frog   170 QFFKWKTVTIAYDDSTGLIRLQELIKAPSRYNLRLKIRQLPIDTKDAKPLLKEMKRGKEFHVIFD 234

  Fly   228 TNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDVDSKRYLEVIN 292
            .:........:..|.:.|....|||:|||.||...|:|.:||:.||:|.||::::::.:.|.:|.
 Frog   235 CSHDMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNIENSQVLSIIE 299

  Fly   293 Q--MQKLQ-----HNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSD 350
            :  |::||     .:||  ::|  ::.|::|||:|:|:..:     :.:.......:.:|.|...
 Frog   300 KWSMERLQAPPKPDSGL--LDG--FMTTDAALMYDAVHVVS-----VAVQQFPQMTVSSLQCNRH 355

  Fly   351 QTWNDGISLYNQINAAITDGLTGTVQF--VEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISD 413
            :.|..|....:.|..|..:||||.:.|  ..|.|..|.||::.||:|.::|:|.|.|..|:|:::
 Frog   356 KPWRFGARFISLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPTSGLNMTE 420

  Fly   414 -----PTAFYDSNIANITLVVMTREERPYVMVKE-DKNLTGNLRFEGFCIDLLKAIATQVGFQYK 472
                 |....|| ::|.:|:|.|..|.||||.|: ||.|.|..||||:|||||:.::..:||:|:
 Frog   421 NQKGKPANITDS-LSNRSLIVTTILEEPYVMFKKSDKPLYGKARFEGYCIDLLEKLSKILGFEYE 484

  Fly   473 IELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKV 537
            :.||.|..||.....|..|||:|:|||:.:||||||.:.|.|.||.|||||||||.|||.||::.
 Frog   485 VRLVEDGKYGAKDDTTQQWNGMVRELMDHKADLAVAPLAITYVREQVIDFTKPFMTLGISILYRK 549

  Fly   538 PTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSIS 602
            |......:|||:|||:.:||:|:|.||:.||..|||:||||||||.|||||..::|:|||.|::.
 Frog   550 PNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLL 614

  Fly   603 NSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDL 667
            |||||..|..::|||.|.|||.|||||||.|:||.||||||||||||||||||||.|||:||.||
 Frog   615 NSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDL 679

  Fly   668 AEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYAFLMES 732
            |:||:|.||.::.|:|||||:.|:|..|:|||.:|.:|..:|.||..|:||:||:...|||||||
 Frog   680 AKQTKIEYGAVQDGATMTFFKKSRIPTYEKMWAFMNSRSQSVLVKNNEEGIQRVLTSDYAFLMES 744

  Fly   733 TMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGD 797
            |.:::..||:|||||||||:||||||:.||.|||:||||::|||:|||:|::.::.:|||:..|
 Frog   745 TTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGVLHMMKEKWWRGNG- 808

  Fly   798 VCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEE 862
             | .:::|||  |:||||:||||:|:||..||.|:|.||:.||.:.|:||...|.:|.||.|.||
 Frog   809 -C-PEEESKE--ASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEE 869

  Fly   863 LRFAMHCHGSKSRHRPR 879
            ||.::.|. .:.:|:|:
 Frog   870 LRMSLKCQ-RRLKHKPQ 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	125/386 (32%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	220/369 (60%)
		Lig_chan	554..828	CDD:459656	168/273 (62%)
grik2	XP_017949808.1	PBP1_iGluR_Kainate	42..419	CDD:380605	125/385 (32%)
		Periplasmic_Binding_Protein_Type_2	435..805	CDD:473866	220/369 (60%)