Protein Alignment CG11155 and grik1

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_004912220.1
• Gene: grik1 / 100493949
• XenbaseID: XB-GENE-957124
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 922
• Identity: 403/922 - (43%)
• Similarity: 575/922 - (62%)
• Gaps: 73/922 - (7%)

  Fly    18 SYLKKICCSYIILSILVISNALPP-----VIRVGAIF--TEDERESSIESAFKYAIYRINKEKTL 75
            |.|:....:.::|..|....|:.|     |:|:|.||  .|:|..:..|.|||:|:..||:.:||
 Frog    15 SVLRMESAARLLLPFLCALAAITPQASQQVLRIGGIFETVENEPINVEELAFKFAVTNINRNRTL 79

  Fly    76 LPNTQLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGR-- 138
            :|||.|.|||:.:...|||..:::.|.||..||.|:|||:.:...|.|||||.|.::|||:.|
 Frog    80 MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWK 144

  Fly   139 ---IDLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLF---NLMHSSTETKA 197
               :|   |...|.|||:|.:..::.|..:::::.:|..|.::||:..||.   .|:.:.:....
 Frog   145 HPSVD---NKDSFFINLHPDYAAISRAVLELVLHYSWKTVTVVYEDSTGLIRLQELIKAPSRYNI 206

  Fly   198 EMYIRQ---ASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDL 259
            ::.|||   .:.|: |.:|:.:::...:.:|.|.:........:.||.:.|....|||.|||.||
 Frog   207 KIKIRQLPSGNKDA-RTLLKEMKKSREFYVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTMDL 270

  Fly   260 ETYDLEDFRYNSVNITAFRLVDVDSKRYLEVINQ--MQKLQ-----HNGLDTINGSPYIQTESAL 317
            ...|||.:||:.||:|.|||:::|:.:...|:.:  |::||     ..||  ::|  .:.|::||
 Frog   271 FALDLEPYRYSGVNMTGFRLLNIDNPQVSSVVEKWSMERLQAPPKPETGL--LDG--MMTTDAAL 331

  Fly   318 MFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF--VEG 380
            |:|:||..|     :.........:.:|.|...:.|..|....:.|..|..|||||.:.|  .:|
 Frog   332 MYDAVYMVA-----VATQRATQMTVSSLQCHRHKPWRFGPRFMSLIKEARWDGLTGRITFNRTDG 391

  Fly   381 RRNIFKLDILKLKQEKIQ---------------KVGYWHPDDGVNISDPTAFYDSNI----ANIT 426
            .|..|.:||:.||::.::               |||.|:.:.|:|::|......:||    ||.|
 Frog   392 LRRDFDMDIISLKEDGMEKAAGETVNHLNKVWKKVGVWNSNTGLNMTDNLKDKSTNITDSLANRT 456

  Fly   427 LVVMTREERPYVMV-KEDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNS 490
            |:|.|..|.||||. |.||.|.||.||||:|:||||.::..:||.|::.||.|..||.. .:...
 Frog   457 LIVTTILEDPYVMFRKSDKPLYGNDRFEGYCLDLLKELSNILGFTYEVRLVVDGKYGAQ-NDKGE 520

  Fly   491 WNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIE 555
            |||:|:||::.:||||||.:||.|.||.||||:||||.|||.||::.|......:|||:|||:.:
 Frog   521 WNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPD 585

  Fly   556 IWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLN 620
            ||:|||.|.:.||..|||:|||:||||.|||||..::|:|||.|::.|||||..|..::|||.|.
 Frog   586 IWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELM 650

  Fly   621 PKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMT 685
            |||.|||||||.|:||.||||||||||||||||||||.|||:||.|||:||:|.||.:..|||||
 Frog   651 PKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMT 715

  Fly   686 FFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGG 750
            ||:.|||..|:|||.:|.:|:....||..::||:||:...||.|||||.::|..||:||||||||
 Frog   716 FFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGG 780

  Fly   751 LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGV 815
            |:||||||:.||.|||:||||::|||:|||:|.:.::.:|||:..|  |..:| |||  |:||||
 Frog   781 LIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG--CPEED-SKE--ASALGV 840

  Fly   816 ENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRPRK 880
            |||||:|:||..||.|:|.|||.||.:.||||.:.|.....:.:.|||..::. |..:.:.:|:.
 Frog   841 ENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNSDIEQCLSFNAIMEELGISLK-HPKRLKKKPKA 904

  Fly   881 R------SCLNC 886
            :      |.|.|
 Frog   905 KGRSSFTSMLTC 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	131/405 (32%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	219/369 (59%)
		Lig_chan	554..828	CDD:459656	169/273 (62%)
grik1	XP_004912220.1	PBP1_iGluR_Kainate	46..439	CDD:380605	131/405 (32%)
		Periplasmic_Binding_Protein_Type_2	454..823	CDD:473866	219/369 (59%)