Protein Alignment CG11155 and grid2

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 960
• Identity: 258/960 - (26%)
• Similarity: 454/960 - (47%)
• Gaps: 148/960 - (15%)

  Fly    42 VIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTKKVCSQLEA 106
            :|.:||||  ||.....:..|:.|:..:|..:.:|...::.:.:.:|..::.|:..::.|..:..
 Frog    26 IIHIGAIF--DESAKKDDEVFRMAVADLNLNEDILQTEKITFSVTFVDGNNPFQAVQEACDLMSQ 88

  Fly   107 GVQAIFGPTDALLASHVQSICEAYDIPHI----------EGRIDLEYNS--KEFSINLYPSHTLL 159
            |:.|:........|..:||:.:|..|||:          .....|:.:|  .::::::.|...|.
 Frog    89 GILALVSSIGCASAGSLQSLADAMHIPHLFIQRSTARTPRSGCGLQRSSGIDDYTLSVRPPVYLN 153

  Fly   160 TLAYRDIMVYLNWTKVAIIYEEDYGL-----------------------FNLMHSSTETKAEMYI 201
            .:..|.:..|. |.|..:.|:.:|.:                       .|:....|...|.|.|
 Frog   154 DVILRVVTEYA-WQKFIVFYDNNYDIRGIQEFLDRVSQQGMDVALQKVENNINRMITGLFATMRI 217

  Fly   202 RQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLED 266
            .:.  :.||..||        :.|:..:|:..|:|...:::..:.....|::....::...|:::
 Frog   218 EEL--NRYRDTLR--------RAILVMSPTTAKAFITEVVETNLVAFDCHWIIINEEINDLDVQE 272

  Fly   267 FRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHN-------GLDTINGS------PYIQT---ES 315
            ....|:.             .|.:|.|...:.||       |...|:.|      |:.|.   .:
 Frog   273 LVRRSIG-------------RLTIIRQTFPVPHNSSQRCFRGNHRISTSLCDPKDPFSQNMEITN 324

  Fly   316 ALMFDSVYAFANGLHFLNLDNHQNFYIKNLSC--TSDQTWNDGISLYNQINAAITDGLTGTVQFV 378
            ..::|:|...||..| ..|::.:...:.:|:|  .:.:.|..|.|:...:......||||.:.|.
 Frog   325 MYIYDTVLLLANAFH-KKLEDRKWHSMASLTCIRKNSKPWQGGRSMLETVKKGGVSGLTGALDFS 388

  Fly   379 E--GRRNIFKLDILKLKQEK-----IQKVGYWHPDDGVNISDPTAFYDSNIANITLVVMTREERP 436
            |  |..||: .:||.....:     |:|:|:|:|..|:|.|......::|:..:.|.|.|..|.|
 Frog   389 EDGGNPNIY-FEILGTNYGEELGRGIRKLGFWNPVTGLNGSLTDRKLENNMRGVVLRVATVLEEP 452

  Fly   437 YVMVKEDKNLTGN-LRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN-SWNGIVQELM 499
            :|||.|  |:.|. .:::||.||:|.|:::.:||:|:|.:..|:.||  .|:.: ||||::.||:
 Frog   453 FVMVSE--NVLGKPKKYQGFSIDVLDALSSYLGFKYEIYVASDHKYG--SPQADGSWNGLIGELL 513

  Fly   500 ERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAY 564
            .:|||:.::::||...||:|:|||..:|:..:|:|.: ...:...:|:.:.|..:.:|..:....
 Frog   514 LKRADMGISALTITPDRENVVDFTTRYMDYSVGVLLR-KAEKTVDMFACLAPFDLSLWACIAGTV 577

  Fly   565 ILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIV 629
            :||...::::      .|.|| |..:...:...  ::.||.||:.|:|::||..:.....:||::
 Frog   578 LLVGLLVYLL------NWLNP-PRLQMGSMTST--TLYNSMWFVYGSFVQQGGEVPYTTLATRMM 633

  Fly   630 GGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTM---------T 685
            .|.|:.|.||:|||||||||||||:.|:.|.|:|..||:.||:|.|||:...:..         .
 Frog   634 MGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNP 698

  Fly   686 FFRDSKIGIYQKMWRYMENRKTAVFVKTYE--DGIKRVMEGSYAFLMESTMLDYAV--QRDCNLT 746
            |.|||   :|.:||| |.||.........|  :||::|..|:|||:.::.:|:|..  .:||:..
 Frog   699 FERDS---MYSQMWR-MINRSNGSENNVQESLEGIQKVKHGNYAFVWDAAVLEYIAINDQDCSFY 759

  Fly   747 QIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKAN 811
            .:|..:..:|||||...|||:||..|..|||||:.|.:.||..|||...|..........:.|.:
 Frog   760 TVGNTIADRGYGIALQHGSPYRDIFSQRILELQQNGDMDILKHKWWPRNGQCELHSSMDTKQKGS 824

  Fly   812 ALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEM-AEEL--RFAMHCHGSK 873
            :|.:::..|||.:|..|:.|:..:|:.|..||.:|.....::....|: .|.|  |....|...:
 Frog   825 SLDIKSFSGVFCILAAGIVLSCFIAMVETWWNKKKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDE 889

  Fly   874 SRHRPRKRSC-----LNCSSVP-------------------TYVPSNVST 899
            |.|:....|.     |:..|:|                   |::|..:.|
 Frog   890 SPHKQFSTSSIDLTPLDIDSLPNRQTLEQISDFRNTHITTTTFIPEQIQT 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	87/428 (20%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	139/383 (36%)
		Lig_chan	554..828	CDD:459656	100/286 (35%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:471960	87/428 (20%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	139/383 (36%)