Protein Alignment CG11155 and grik3

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 947
• Identity: 387/947 - (40%)
• Similarity: 567/947 - (59%)
• Gaps: 85/947 - (8%)

  Fly    17 RSYLKKICCSYIILSILVISNALPPVIRVGAIFTEDERE----SSIESAFKYAIYRINKEKTLLP 77
            |.|::......::|..:..|..:|.|||:|.||.:.:..    ||.|.|||:|:..||:.:||||
Zfish     5 REYVEYRSAIIVVLFWIQSSFGMPHVIRIGGIFEQTDGPVALVSSEELAFKFAVNNINRNRTLLP 69

  Fly    78 NTQLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGR---- 138
            ||.|.|||:.:...|||..::|.|.||..||.|||||:.:..::.|||||.|.::|||:.|
Zfish    70 NTTLTYDIQRINIYDSFEASRKACDQLSLGVVAIFGPSHSSSSNAVQSICNALEVPHIQVRWKHH 134

  Fly   139 -IDLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMH---SSTETKAEM 199
             :|   |...|..||||.::.|:.|..|::.:|.|....::|::..||..|..   :.:.....:
Zfish   135 PMD---NRDTFYANLYPDYSSLSYAILDLVQFLKWKTATVVYDDSTGLIRLQELIMAPSRYNIRL 196

  Fly   200 YIRQASPDSY--RQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETY 262
            .|||...|:.  |.:|:.:::...::||.|.:.:......:....:.|....|||:|||.||...
Zfish   197 KIRQLPMDTVDTRPLLKEMKRSREFRIIFDCSHTMAAQILKQAQMMGMMTEYYHYIFTTLDLMAI 261

  Fly   263 DLEDFRYNSVNITAFRLVDVDSKRYLEVI------NQMQKLQHNGLDTINGSPYIQTESALMFDS 321
            :||.:|:..||:|.||:::||:.:...::      .|:.....:||  :.|  .:.|::||.:|:
Zfish   262 NLEPYRFCGVNMTGFRILNVDNPQVASIVEKWSLERQIPPKPDSGL--LEG--IMTTDAALTYDA 322

  Fly   322 VYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF--VEGRRNI 384
            |:..:     ::..:.....:.:|.|...:.|..|....:.|..:..|||||.:.|  ..|.|..
Zfish   323 VHIVS-----VSYQHAPQMTVNSLQCHRHKPWRFGGRFMSFIKESHWDGLTGRLCFNRTTGLRTD 382

  Fly   385 FKLDILKLKQEKIQKVGYWHPDDGVNISDPTAFYDSNI----ANITLVVMTREERPYVMVKE-DK 444
            |.|||:.||::.:||||.|....|:||::.......||    :|.:||:.|..|.||||:|: ||
Zfish   383 FDLDIVSLKEDGLQKVGKWSASGGLNITEVPRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDK 447

  Fly   445 NLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVAS 509
            .|.||.|||||||||||.:|:.:||.|:|.||||..|| :..:...|||:::||||.|||||||.
Zfish   448 ALVGNDRFEGFCIDLLKELASILGFSYEIHLVPDGKYG-FQDDKGQWNGMIRELMEHRADLAVAP 511

  Fly   510 MTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVM 574
            :||.:.||..|||:|||:|.||.||::.|.|..:..|||:||:..:||:|:|.||:.||..|||:
Zfish   512 LTITFMREKAIDFSKPFLNTGISILYRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVI 576

  Fly   575 ARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLI 639
            ||||||||.:.|||...:|:|||.|::.|||||..|:.::|||.|.|||.||||:||.|:||.||
Zfish   577 ARFSPYEWYDAHPCNPGSDVVENNFTLLNSFWFGVGSLMQQGSELMPKALSTRIIGGIWWFFTLI 641

  Fly   640 IISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMEN 704
            ||||||||||||||||||.||::||.|||:||:|.||.::.|:||:||:.|::..::|||.:|.:
Zfish   642 IISSYTANLAAFLTVERMDSPVDSADDLAKQTKIEYGVVKDGATMSFFKKSRVSTFEKMWAFMSS 706

  Fly   705 RKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRD 769
            |::..|||:.||||:||::..||.|||||.::|..:|:|||||:||::|||||||.||||||:||
Zfish   707 RQSTSFVKSIEDGIQRVLKSDYALLMESTTIEYVTRRNCNLTQVGGIIDSKGYGIGTPKGSPYRD 771

  Fly   770 KISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVV 834
            ||::|||.:.|.|.:.:|.:|||  :|..|..|::   .:...:|::|:||:|:||..||.|:|.
Zfish   772 KITIAILGILEDGRLHMLKEKWW--SGSSCLEDER---YETGPMGIQNLGGIFIVLASGLVLSVF 831

  Fly   835 VAIFEFCWNSRKNLNTENQSL-CSEMAEEL--------------RFAMHCHGSKS---------- 874
            |||.||.:..||....|...| |.:..::.              ..|.|....:|
Zfish   832 VAIGEFIYKLRKTAEREQVFLQCGDGRDQTVVHVRETGEAQAPPAAASHAEDGRSDQHALLQRPS 896

  Fly   875 ---------RHRPRKRSCLNC------SSVPTYVPSN 896
                     :||...|..:.|      ..||..||.:
Zfish   897 PARKGQHELQHRDDARVSMTCLGDGHLRHVPGAVPES 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	127/390 (33%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	215/369 (58%)
		Lig_chan	554..828	CDD:459656	153/273 (56%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	126/389 (32%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	214/368 (58%)