Protein Alignment CG11155 and grin3bb

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 983
• Identity: 224/983 - (22%)
• Similarity: 387/983 - (39%)
• Gaps: 252/983 - (25%)

  Fly    43 IRVGAIFTEDERES-SIESAFKYAIYRINKEKTLLPNTQLVYD--IEYVPRD----DSFRTTKKV 100
            :|:||:.  ..|:| .:.:|...|:..:.:.    .|..|.|:  ::.|.|:    |.....:.|
Zfish    47 VRLGALL--PPRQSVRVRAALHRALSGLAES----GNNFLPYNLSLDVVAREAQSGDPESLFRCV 105

  Fly   101 CSQLEA-GVQAI--FGPTDALLASHVQSICEAYDIPHI-----------EGRIDLEYNSKEFSIN 151
            |..:.. ||.|:  |..|...:. .::.:....:||.|           :.|..|:..::
Zfish   106 CQDIVVQGVSAVLAFPQTQEEIV-QMEFMSSFLEIPFISIIEHGEPLKTQNRFHLQMTTR----- 164

  Fly   152 LYPS---HTLLTLAYRDIMVYLNWTK-VAIIYE--EDYGL----------------------FNL 188
            :.||   ..||.:..|.     .|.: :|::..  ||.||                      .||
Zfish   165 IPPSGLVELLLAVLQRS-----GWEESMAVLCHGWEDAGLLDLLKLQGRFGWGPSQWHLRAALNL 224

  Fly   189 MHSS------TETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMND 247
            .||:      ::..:|.:....||.:  .||           :...:|....|..||...|.:..
Zfish   225 SHSTARMANISDFLSEHFNLDHSPPA--SVL-----------LFGADPECASSVLRSAHDLGLTL 276

  Fly   248 HRYHYMFTTFDLETYDLEDFRYNSVNITAFRLV--DVDSKRY-------LEVINQMQKLQHNGLD 303
            ...|::.      .:.|.....:|:.:....|.  :||.|..       |::||:
Zfish   277 PTVHWIM------GHPLSPDALHSIGLPLGLLAYGEVDHKPLDFYISDALQLINR---------- 325

  Fly   304 TINGSPYIQTESALMFDSVYAFAN-GLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAI 367
            .:..:..::.:.||:.:.|..|.. ..|  .|.:...:..:.||.||
Zfish   326 AVTAATVVRPDLALIQNMVNCFDKPNKH--ELPSSGQYIARFLSNTS------------------ 370

  Fly   368 TDGLTGTVQFVEGRRNI------FKLDILKLKQEKIQK-----VGYWHPDDG-VNISDPTAFYDS 420
            ..||||.|..   :||:      .|:.|..|:::.:.:     ||.|  :.| :|:.:...:..|
Zfish   371 FVGLTGPVIV---QRNLSRVHTSHKVHIWSLRRDAVGQPTWVTVGSW--EGGRLNVEEQGLWQGS 430

  Fly   421 N---------------------IANITLVVMTREERPYVM---VKEDKN---------------- 445
            :                     ::...|.|:|..|.|:|.   |.||.|
Zfish   431 SPRQRTEGQMGREGRRWRAGFPVSGSRLRVVTLVEHPFVFTREVDEDGNCPAGQYCLDAGTNSSE 495

  Fly   446 ---------LTGNLRF---------EGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWN 492
                     ..||..|         .|:|||||:.::..:.|::.:.:|.|..||..  :...|.
Zfish   496 TLDHLYAERAQGNKSFLPPDYSKCCYGYCIDLLEKLSEDMNFEFDLYIVGDGKYGAV--KGGQWT 558

  Fly   493 GIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFK-VPTSQPTRLFSFMNPLAIEI 556
            |:|.:|:...||:||.|.:||.||..|||||.||.:..:|||.: ..|:.|  :.:||.||...:
Zfish   559 GLVGDLLSGVADMAVTSFSINSARSKVIDFTSPFFSTSLGILVRSKDTAAP--IGAFMWPLHWSM 621

  Fly   557 WLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQ---FSISNSFWFITG-TFLRQGS 617
            |:.:..|..:.  |||:    :.||||:|   :..|....|:   ||.|::...... .|.|..|
Zfish   622 WMGIFVALHIT--ALFL----TLYEWKSP---FGMTPHGRNRVKVFSYSSALNLCYAILFGRTVS 677

  Fly   618 GLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASD--LAEQTE-ISYGTLE 679
            ...||..:.|.:...|..|||:::|||||||||.:..|:....:....|  |...:: ..:||:.
Zfish   678 SKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFEEVSGIHDAKLHHPSQGFRFGTVR 742

  Fly   680 GGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGS---YAFLMESTMLDY--AV 739
            ..|...:.:.|...:::.|.::.|        .|..||:..:....   .||:|:..:|||  ::
Zfish   743 ESSAEDYMKKSFPEMHEYMRKFNE--------PTTPDGVATLKTDPPQLDAFIMDKALLDYEVSI 799

  Fly   740 QRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDK 804
            ..||.|..:|.....:||||..|:.||....||..:...:..|.:.:|:|||:|..  .|.: ..
Zfish   800 DADCKLLTVGKPFAIEGYGIGLPQNSPLTSNISEFVSRYKSDGYMDMLHDKWYKVV--PCGK-RV 861

  Fly   805 SKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHC 869
            ...::...:|:.:..|:||:|..|:..|::....|..:         .:.:...:..:.:|....
Zfish   862 FAVTETLQMGIRHFSGLFVLLCVGVTGALLTLAGEHAF---------YRLVLPHIRRKQKFKYWL 917

  Fly   870 HGSKSRHR 877
            |.|:..||
Zfish   918 HTSQKIHR 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	85/445 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	123/418 (29%)
		Lig_chan	554..828	CDD:459656	77/285 (27%)
grin3bb	XP_017213803.2	Periplasmic_Binding_Protein_type1	39..427	CDD:471960	85/450 (19%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	122/415 (29%)
		Lig_chan	618..885	CDD:459656	77/286 (27%)