DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11155 and LOC100331381

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_017207884.1	Gene:	LOC100331381 / 100331381	-ID:	-	Length:	1063	Species:	Danio rerio

Alignment Length:	914	Identity:	366/914 - (40%)
Similarity:	521/914 - (57%)	Gaps:	63/914 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IILSILVISNALPP---VIRVGAIFTEDERESSIESAFKYAIYR--INKEKTLLPNTQLVYDIEY 87
            ::|::...|::..|   .:|:.||. :|:...........|:.|  ||.........::..||..
Zfish    18 LLLTMAPSSHSQVPALSAVRMAAIL-DDQSACGRGERLALALARENINSLMEGPARARVEVDIFE 81

  Fly    88 VPRDDSFRTTKKVCSQLEAGVQAIFGPTDA-LLASHVQSICEAYDIPHI----EGRIDLEYNSKE 147
            :.||..:.||..:|..|..||.::.||..: ...|.|..||...:||||    |....|.| .:.
Zfish    82 LQRDSQYETTDTMCQILPKGVVSVIGPASSPASGSTVSHICGEKEIPHIKIGPEETPRLPY-LRF 145

  Fly   148 FSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMH------SSTET-KAEMYIRQAS 205
            .|:.||||:..|:||...|:....:...::|..:...|..|..      .|.|| ...|......
Zfish   146 ASVTLYPSNEDLSLAIGAILRSFGYPTASLICAKAECLLRLEELVRHFLISRETLSVRMLDENLD 210

  Fly   206 PDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYN 270
            |   ..:|:.||..::..||:|.|.|......:...:|.|....|.|:.||.|.....|:|...:
Zfish   211 P---TPLLKEIRDDKVATIIIDANASVSILILKKASELGMTSAFYKYILTTMDFPLLRLDDVVND 272

  Fly   271 SVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPY--IQTESALMFDSVYAFANGLHFLN 333
            ..||..|.:::.....|||.|..:......|.|.   |||  ....||||||:|:.....:..||
Zfish   273 QSNIVGFSMLNNSHPFYLEFIRSLNLSWREGCDL---SPYPGPALSSALMFDAVHVVVGAVRELN 334

  Fly   334 LDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQF-VEGRRNIFKLDILKLKQEKI 397
              ..|...:|.|||||...|..|.||.|.:.....|||||.|:| .:|:|..:.|.||:..:...
Zfish   335 --RSQEIGVKPLSCTSSLIWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKFKGGH 397

  Fly   398 QKVGYWHPDDGVNISDPTAFYDSN--IANITLVVMTREERPYVMVKED-KNLTGNLRFEGFCIDL 459
            :::|.|:.::.:.::..:...:::  :||.||.|.|..|.||||.||: ::..|:.::||||:|:
Zfish   398 KEIGVWYSNNTLAMNSTSLDINTSETLANKTLTVTTILENPYVMRKENYQDFQGSDQYEGFCVDM 462

  Fly   460 LKAIATQVGFQYKIELVPDNMYGVYIPETN-SWNGIVQELMERRADLAVASMTINYARESVIDFT 523
            |:.:|..:.|.::|:||.|.:||.  ||.| ||.|:|.||:.|:||||||..||...||.||||:
Zfish   463 LRELADILKFSFRIKLVDDGLYGA--PEPNGSWTGMVGELINRKADLAVAGFTITSEREKVIDFS 525

  Fly   524 KPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPC 588
            ||||||||.||::|...:....|||::|.:..:||::|.||:.||..||:.||.|||||.||.||
Zfish   526 KPFMNLGISILYRVHIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPFPC 590

  Fly   589 YKE-TDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFL 652
            ::| .|::|||:::.||.||..|.|::|||.:.|:|.|||.|.|.|:.|.|||||||||||||||
Zfish   591 WRERRDLLENQYTLGNSLWFPIGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFL 655

  Fly   653 TVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDG 717
            ||:||..|||||.|||:||.|.|||::||||||||.:|:...||:||.||.:::.:||||:.|:|
Zfish   656 TVQRMEVPIESAEDLADQTNIQYGTIQGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEG 720

  Fly   718 IKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKG 782
            |.||:...||||:||||.:|..:.:|||||||||||:|||||..|.|||:||:|:|.||:|||..
Zfish   721 IARVLNSKYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLGILQLQENN 785

  Fly   783 IIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKN 847
            .::||..:||:  |..|.   |.::.:|..||::||||:||||:|||.:||.|||.||.|::|::
Zfish   786 RLEILKRRWWE--GGKCL---KEEDHRAKGLGMDNIGGIFVVLICGLIIAVFVAIMEFVWSTRRS 845

  Fly   848 LNTE---------------NQSLCSEMAEELRFAMHCHGSKSRHRPRKRSCLNCSSV---PTYVP 894
            ..|:               ..|:|.||..|.|..:.|   |...|.|:|...:...|   |..:|
Zfish   846 AETDEVRPHPCPVRNHRHARVSVCQEMMTEFRNVISC---KKNSRLRRRRAFSSQGVLRHPARLP 907

  Fly   895 SNVS 898
            ...|
Zfish   908 LGAS 911

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	112/382 (29%)
		ANF_receptor	61..393	CDD:279440	106/348 (30%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	207/371 (56%)
		Lig_chan	555..829	CDD:278489	157/274 (57%)
LOC100331381	XP_017207884.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60688at33208
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920