DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11155 and si:dkey-183j2.10

DIOPT Version :9

Sequence 1:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_001923977.1	Gene:	si:dkey-183j2.10 / 100151589	ZFINID:	ZDB-GENE-130530-729	Length:	465	Species:	Danio rerio

Alignment Length:	438	Identity:	157/438 - (35%)
Similarity:	253/438 - (57%)	Gaps:	25/438 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 LVVMTREERPYVMVKEDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSW 491
            |:|.|.::.||.|.|       ..:.||:|:|||..:|.::||:||:.||.|..||.. .|..:|
Zfish    31 LIVTTIKQDPYTMSK-------GSQLEGYCMDLLTELAKKLGFKYKVHLVKDGSYGRQ-DENGNW 87

  Fly   492 NGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILF-KVPTSQPTRLFSFMNPLAIE 555
            ||::.|::...||||||.:|:..|||..:..|||:|..||.||. |...|:....|.|::|.:.|
Zfish    88 NGMIGEVVRGEADLAVAPLTLTAAREKAVGMTKPYMQTGISILLRKDIVSEEAGFFDFLSPFSGE 152

  Fly   556 IWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLN 620
            .|..:|.||.:.:..:.::.|.||.||..|     ||:  .|.|::.:|.|:..|....||:|.:
Zfish   153 TWFGILIAYFVTAVCICIVGRLSPCEWSQP-----ETE--PNHFTLLHSLWYTAGALSLQGAGPH 210

  Fly   621 PKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMT 685
            |||.|.|::...|:.|.:::::.|.::|::....:.....|:...|||.|..|.||||.|.||:.
Zfish   211 PKAVSGRVISCTWWLFAVVLLACYFSSLSSTQGSDSAPLMIKGFEDLANQDVIEYGTLAGSSTLA 275

  Fly   686 FFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGG 750
            ||::|....|::::.:||.||:  ||.:.::|:::..||:|||:.||..||.||.|.|.|.:...
Zfish   276 FFKNSNNPSYRRIYEHMERRKS--FVSSMDEGVQKAKEGNYAFIGESVSLDLAVARHCELVRAHE 338

  Fly   751 LLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGV 815
            ::..:||.|.||.||.....:|:|||:|.|.|.:..|..|||.::   |..|:    :||::|..
Zfish   339 VIGMRGYSIVTPLGSAMLKNLSVAILQLSEAGELAYLRTKWWASS---CLPDN----AKASSLRA 396

  Fly   816 ENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEEL 863
            .::.|:|:||..||.:.|::::||....||.....:.:|.|:.:.:||
Zfish   397 HSMKGIFLVLAIGLGIGVLLSLFELTTKSRSAAGEQKKSCCTVLTQEL 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377
		ANF_receptor	61..393	CDD:279440
		PBP2_iGluR_Kainate	424..793	CDD:270432	136/366 (37%)
		Lig_chan	555..829	CDD:278489	95/273 (35%)
si:dkey-183j2.10	XP_001923977.1	PBP2_iGluR_non_NMDA_like	28..381	CDD:270403	136/366 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910