Protein Alignment CG11155 and grin2db

DIOPT Version :10

• Sequence 1: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: XP_073782035.1
• Gene: grin2db / 100149482
• ZFINID: ZDB-GENE-100920-7
• Length: 1984
• Species: Danio rerio
• Alignment Length: 619
• Identity: 166/619 - (26%)
• Similarity: 267/619 - (43%)
• Gaps: 143/619 - (23%)

  Fly   343 KNLSCTSDQTWND--------GISLYNQINAAITD--GLTGTVQFV-------------EGRRNI 384
            |.|.....|.|.|        |:|:......|:..  |.||...||             .||...
Zfish   327 KRLFAVRPQGWRDEPRRRIARGVSILTHGAVALRKDYGATGGPHFVTNCQTDGNRTQRIRGRMRY 391

  Fly   385 FK---------------------LDILKLKQ-EKIQKVGYWH--------------------PDD 407
            |.                     ||::.... ...:.||:|.                    |||
Zfish   392 FSNITLGGRDYSFSNEGYLANPFLDVISYTPGSGWEDVGWWENGVLRLRYPAWSRYGPFLQPPDD 456

  Fly   408 GVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNLTGN-LR-------------------- 451
            ..:                |.|:|.||||:|:|:.....:|. :|
Zfish   457 AQH----------------LRVVTLEERPFVIVELADAASGTCIRDSVPCRRPLNASALQEGVAP 505

  Fly   452 ----FEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTI 512
                .:|||||:||.:|..|||.|.:.||.:..:|..|  ...|||:|.|::.:|||:|:.|:||
Zfish   506 VKQCCKGFCIDILKRLARIVGFTYDLYLVTNGKHGKKI--DGVWNGMVGEVVYKRADMAIGSLTI 568

  Fly   513 NYARESVIDFTKPFMNLGIGILFKVP--TSQPTRLFSFMNPLAIEIWLYVLAAYI-LVSFALFVM 574
            |..|..|:||:.||:..||.::....  |..|:   :|:.|.:..:|:.:....: :|:..:|:.
Zfish   569 NEERSEVVDFSVPFVETGISVMVSRSNGTVSPS---AFLEPYSPAVWVMMFVMCLTVVAVTVFIF 630

  Fly   575 ARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGL-NPKATSTRIVGGCWFFFCL 638
            ..|||..:.......|:..  .::|:|..|.|.:..........: |||.|:::|:...|.||.:
Zfish   631 EFFSPVGYNRSLQSGKKAG--GSKFTIGKSIWLLWALVFNNSVPVENPKGTTSKIMVLVWAFFAV 693

  Fly   639 IIISSYTANLAAFLTVERMISPIESASDLAEQ--TE----ISYGTLEGGSTMTFFRDSKIGIYQK 697
            |.::|||||||||:..|..|..:...||...|  ||    :.:||:..|||....|.:...::|.
Zfish   694 IFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYPDMHQY 758

  Fly   698 MWRYMENRKTAVFVKTYEDGIKRVMEGSY-AFLMESTMLDYAVQRD--CNLTQIGG--LLDSKGY 757
            |.:|.:        |:.||.|..:..|.. ||:.::.:|:|..::|  |.:..||.  :..:.||
Zfish   759 MVKYNQ--------KSVEDAISHLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGY 815

  Fly   758 GIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVF 822
            |||..|.|.|:..:.||:|:|.....|::|...|   ...:|:.|  ..|..::.|.::|:.|||
Zfish   816 GIALIKNSRWKRPLDLALLQLVGDDEIEMLERLW---LSGICHND--KIEVMSSKLDIDNMAGVF 875

  Fly   823 VVLLCGLALAVVVAIFEFC--WNSRKNLNTENQS 854
            .:||..:.|:::|..:|..  |..|..::...||
Zfish   876 YMLLVAMGLSLLVFAWEHLVYWRLRHCMSKMGQS 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	24/134 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	125/408 (31%)
		Lig_chan	554..828	CDD:459656	83/286 (29%)
grin2db	XP_073782035.1	None