Protein Alignment Kif3C and KAR3

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_015467.1
• Gene: KAR3 / 856263
• SGDID: S000006345
• Length: 729
• Species: Saccharomyces cerevisiae
• Alignment Length: 370
• Identity: 148/370 - (40%)
• Similarity: 200/370 - (54%)
• Gaps: 57/370 - (15%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEF-------AVSVTNPSARISQQKKFIFDSVYNMKTDT 61
            ||:|..|.||..: ..|.:..:::.:|||       ::.||. ....:|..:|.||.:::.: ||
Yeast   386 NIRVYCRIRPALK-NLENSDTSLINVNEFDDNSGVQSMEVTK-IQNTAQVHEFKFDKIFDQQ-DT 447

  Fly    62 EVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTM--QGDENFSNSTGIIPKCFDHIFERIS- 123
            .|...:....||:|:::|||..||||||||.|||.||  .||       ||||....|||..|:
Yeast   448 NVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGD-------GIIPSTISHIFNWINK 505

  Fly   124 -MTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGV------SVPTLTTQPVVN 181
             .|....|.....::|||||.|.||| :::|.|      ||...||:      ...|.|| .:.|
Yeast   506 LKTKGWDYKVNCEFIEIYNENIVDLL-RSDNNN------KEDTSIGLKHEIRHDQETKTT-TITN 562

  Fly   182 ANQC--------YDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDA-FGGICR 237
            ...|        ...|...||.|.||:|..|::|||||:||.|.|.        ||:| .|....
Yeast   563 VTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLS--------GSNAKTGAHSY 619

  Fly   238 GKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSL--VDGKAKHVPFRDSKLTRLL 300
            |.|:|||||||||...:...||||:|...||.|||.||:||.:|  .|...:|:|||:||||.||
Yeast   620 GTLNLVDLAGSERINVSQVVGDRLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLL 684

  Fly   301 QDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAKN---ISNK 342
            |.||.|::||||...|||:..|.:||:::||:||:..:   :|.|
Yeast   685 QYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLVSRK 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	146/365 (40%)
KAR3	NP_015467.1	SMC_prok_B	<83..389	CDD:274008	2/2 (100%)
		KISc_C_terminal	384..725	CDD:276817	146/364 (40%)